Item Type | Name |
Academic Article
|
Expression of the c-myb proto-oncogene in bovine vascular smooth muscle cells.
|
Academic Article
|
Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice.
|
Academic Article
|
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
|
Academic Article
|
Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.
|
Academic Article
|
Adenoviral expression of murine serum amyloid A proteins to study amyloid fibrillogenesis.
|
Academic Article
|
Effect of nicotine use and withdrawal on brain preproenkephalin A mRNA.
|
Academic Article
|
Arachidonic acid and leukotriene C4: role in transient cerebral ischemia of gerbils.
|
Academic Article
|
Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis.
|
Academic Article
|
Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis.
|
Academic Article
|
Amyloid formation in the rat: adenoviral expression of mouse serum amyloid A proteins.
|
Academic Article
|
Expression of mouse acute-phase (SAA1.1) and constitutive (SAA4) serum amyloid A isotypes: influence on lipoprotein profiles.
|
Academic Article
|
Increased serum amyloid a levels reflect colitis severity and precede amyloid formation in IL-2 knockout mice.
|
Academic Article
|
Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury.
|
Academic Article
|
Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.
|
Academic Article
|
Induction of the protooncogene c-fos and recovery of cytosolic adenosine triphosphate in reperfused liver after transient warm ischemia: effect of nitrone free-radical spin-trap agents.
|
Academic Article
|
Hyperglycemia suppresses c-fos mRNA expression following transient cerebral ischemia in gerbils.
|
Academic Article
|
Regulation of expression of the growth-state-related genes 2F1 and 2A9 during entry of quiescent smooth muscle cells into the cell cycle.
|
Academic Article
|
In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice.
|
Academic Article
|
Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines.
|
Academic Article
|
A mouse model for serum amyloid A amyloidosis.
|
Academic Article
|
Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.
|
Academic Article
|
Abeta deposition is essential to AD neuropathology.
|
Academic Article
|
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
|
Academic Article
|
Hormonal regulation of matrix metalloproteinase inhibitors in rat granulosa cells and ovaries.
|
Academic Article
|
In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.
|
Academic Article
|
Age-related differential expression of neuropeptide mRNAs in Aplysia.
|
Academic Article
|
Oxidized high-density lipoprotein induces neuron death.
|
Academic Article
|
ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
|
Academic Article
|
Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.
|
Academic Article
|
Establishment of epidermal cell lines derived from the skin of the Atlantic bottlenose dolphin (Tursiops truncatus).
|
Academic Article
|
Developmental expression of the Xenopus laevis fos protooncogene.
|
Academic Article
|
Inducible ornithine decarboxylase expression in brain subject to vasogenic oedema after transient ischaemia: relationship to C-fos gene expression.
|
Academic Article
|
Expression of mouse apolipoprotein SAA1.1 in CE/J mice: isoform-specific effects on amyloidogenesis.
|
Academic Article
|
Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease.
|
Academic Article
|
JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.
|
Academic Article
|
Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics.
|
Academic Article
|
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
|
Academic Article
|
Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.
|
Academic Article
|
Focal cerebral ischemia in the TNFalpha-transgenic rat.
|
Academic Article
|
Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system.
|
Academic Article
|
Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.
|
Academic Article
|
Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: preclinical refinement and optimization.
|
Academic Article
|
The vitamin D3 transcriptomic response in skin cells derived from the Atlantic bottlenose dolphin.
|
Academic Article
|
Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor.
|
Academic Article
|
The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury.
|
Academic Article
|
Isolation of a new member of the S100 protein family: amino acid sequence, tissue, and subcellular distribution.
|
Academic Article
|
Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis.
|
Academic Article
|
Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice.
|
Academic Article
|
Expression of proenkephalin mRNA in developing cerebellar cortex of the rat: expression levels coincide with maturational gradients in Purkinje cells.
|
Academic Article
|
Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of A?PP transgenic mice.
|
Academic Article
|
The cysteine protease inhibitor, E64d, reduces brain amyloid-? and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, ?-secretase activity.
|
Academic Article
|
Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.
|
Academic Article
|
The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
|
Academic Article
|
Nanoparticles for targeted delivery of antioxidant enzymes to the brain after cerebral ischemia and reperfusion injury.
|
Academic Article
|
Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.
|
Academic Article
|
Fibroblast growth factor-18 reduced infarct volumes and behavioral deficits after transient occlusion of the middle cerebral artery in rats.
|
Academic Article
|
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
|
Academic Article
|
A contusion model of severe spinal cord injury in rats.
|
Academic Article
|
Serum deprivation of vascular smooth muscle cells enhances collagen gene expression.
|
Academic Article
|
Complex regulation of collagen gene expression in cultured bovine aortic smooth muscle cells.
|
Academic Article
|
Regulation of oncogene expression in cultured aortic smooth muscle cells. Post-transcriptional control of c-myc mRNA.
|
Academic Article
|
Tyrosine phosphorylation of microtubule-associated protein kinase after transient ischemia in the gerbil brain.
|
Academic Article
|
Calcium/calmodulin dependent protein kinase II mRNA in the gerbil brain after cerebral ischemia.
|
Academic Article
|
Role of calcium in inactivation of calcium/calmodulin dependent protein kinase II after cerebral ischemia.
|
Academic Article
|
Ontogeny of proenkephalin mRNA and enkephalin peptide expression in the cerebellar cortex of the rat: spatial and temporal patterns of expression follow maturational gradients in the external granular layer and in Purkinje cells.
|
Academic Article
|
Mouse serum amyloid A protein (SAA5) structure and expression.
|
Academic Article
|
Role of protein synthesis, prostaglandins, and estrogen in rat ovarian metalloproteinase inhibitor production.
|
Academic Article
|
Cell proliferation and protooncogene induction in oligodendroglial progenitors.
|
Academic Article
|
Structure of the mouse Saa4 gene and its linkage to the serum amyloid A gene family.
|
Academic Article
|
Induction of PGH synthase and c-fos mRNA during early reperfusion of ischemic rat brain.
|
Academic Article
|
Dose-dependent effects of aluminum on osteocalcin synthesis in osteoblast-like ROS 17/2 cells in culture.
|
Academic Article
|
Beneficial effects of S-adenosyl-L-methionine on blood-brain barrier breakdown and neuronal survival after transient cerebral ischemia in gerbils.
|
Academic Article
|
Time window of fibroblast growth factor-18-mediated neuroprotection after occlusion of the middle cerebral artery in rats.
|
Academic Article
|
Neprilysin regulates amyloid Beta peptide levels.
|
Academic Article
|
Ischemic induction of protooncogene expression in gerbil brain.
|
Academic Article
|
Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice.
|
Academic Article
|
Selective effects of behaviorally active doses of methamphetamine on mRNA expression in the gerbil brain.
|
Academic Article
|
Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors.
|
Academic Article
|
Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage.
|
Academic Article
|
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
|
Academic Article
|
Modulation of ornithine decarboxylase mRNA following transient ischemia in the gerbil brain.
|
Academic Article
|
Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
|
Academic Article
|
Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death.
|
Academic Article
|
Complement-dependent P-selectin expression and injury following ischemic stroke.
|
Academic Article
|
A dolphin peripheral blood leukocyte cDNA microarray for studies of immune function and stress reactions.
|
Academic Article
|
Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta.
|
Academic Article
|
Neprilysin protects neurons against Abeta peptide toxicity.
|
Academic Article
|
Semi-allogeneic vaccine for T-cell lymphoma.
|
Academic Article
|
Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.
|
Academic Article
|
Delta 2-specific opioid receptor agonist and hibernating woodchuck plasma fraction provide ischemic neuroprotection.
|
Academic Article
|
Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
|
Academic Article
|
The dual role of tumor necrosis factor-alpha in the pathophysiology of spinal cord injury.
|
Academic Article
|
Motoneuronotrophic factor analog GM6 reduces infarct volume and behavioral deficits following transient ischemia in the mouse.
|
Academic Article
|
Semi-allogeneic vaccines and tumor-induced immune tolerance.
|
Academic Article
|
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
|
Academic Article
|
Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
|
Academic Article
|
The impact of methylmercury on 1,25-dihydroxyvitamin D3-induced transcriptomic responses in dolphin skin cells.
|
Academic Article
|
A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.
|
Academic Article
|
Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease.
|
Academic Article
|
Transcranial laser therapy attenuates amyloid-? peptide neuropathology in amyloid-? protein precursor transgenic mice.
|
Academic Article
|
Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.
|
Academic Article
|
Targets for AD treatment: conflicting messages from ?-secretase inhibitors.
|
Academic Article
|
Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.
|
Academic Article
|
Protective effects of incensole acetate on cerebral ischemic injury.
|
Academic Article
|
Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing A?PP containing the wild-type ?-secretase site sequence.
|
Academic Article
|
Heparin prevents vascular smooth muscle cell progression through the G1 phase of the cell cycle.
|
Academic Article
|
Expression of mRNAs for PPT, CGRP, NF-200, and MAP-2 in cocultures of dissociated DRG neurons and skeletal muscle cells in administration of NGF or NT-3.
|
Academic Article
|
Biomaterial-based interventions for neuronal regeneration and functional recovery in rodent model of spinal cord injury: a systematic review.
|
Academic Article
|
Independent regulation of transcription of the two strands of the c-myc gene.
|
Academic Article
|
Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact.
|
Academic Article
|
Association of apolipoprotein E with murine amyloid A protein amyloid.
|
Academic Article
|
Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus.
|
Academic Article
|
Ontogeny and effect of activity on proenkephalin mRNA expression during development of the chick spinal cord.
|
Academic Article
|
Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage.
|
Academic Article
|
Serum amyloid A protein family. Differential induction by oxidized lipids in mouse strains.
|
Academic Article
|
Structural prerequisites for serum amyloid A fibril formation.
|
Academic Article
|
Inhibition of tyrosine phosphorylation prevents delayed neuronal death following cerebral ischemia.
|
Academic Article
|
Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors.
|
Concept
|
Disease Models, Animal
|
Concept
|
Animals, Newborn
|
Concept
|
Animals
|
Concept
|
Behavior, Animal
|
Concept
|
Animals, Genetically Modified
|
Concept
|
Physical Conditioning, Animal
|
Concept
|
Models, Animal
|
Academic Article
|
The cysteine protease cathepsin B is a key drug target and cysteine protease inhibitors are potential therapeutics for traumatic brain injury.
|
Academic Article
|
Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
|
Academic Article
|
Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.
|
Academic Article
|
Single-neuron axonal pathfinding under geometric guidance: low-dose-methylmercury developmental neurotoxicity test.
|
Academic Article
|
Proteomic analysis of cerebrospinal fluid in California sea lions (Zalophus californianus) with domoic acid toxicosis identifies proteins associated with neurodegeneration.
|
Academic Article
|
Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement.
|
Academic Article
|
Prolonging life in chick forebrain-neuron culture and acquiring spontaneous spiking activity on a microelectrode array.
|
Academic Article
|
SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
|
Academic Article
|
A therapeutic cancer vaccine against GL261 murine glioma.
|
Academic Article
|
Dietary supplementation of GrandFusion(?) mitigates cerebral ischemia-induced neuronal damage and attenuates inflammation.
|
Academic Article
|
The Fli-1 transcription factor is a critical regulator for controlling the expression of chemokine C-X-C motif ligand 2 (CXCL2).
|
Academic Article
|
RhoA knockdown by cationic amphiphilic copolymer/siRhoA polyplexes enhances axonal regeneration in rat spinal cord injury model.
|
Academic Article
|
Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms.
|
Academic Article
|
Non-genomic oestrogen receptor signal in B lymphocytes: An approach towards therapeutic interventions for infection, autoimmunity and cancer.
|
Academic Article
|
High-Sodium Diet Has Opposing Effects on?Mean Arterial Blood Pressure and?Cerebral Perfusion in a Transgenic Mouse Model of Alzheimer's Disease.
|
Academic Article
|
Daily supplementation with GrandFusion? improves memory and learning in aged rats.
|
Academic Article
|
The Effect of Diet on Improved Endurance in Male C57BL/6 Mice.
|
Academic Article
|
Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy.
|
Academic Article
|
Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements.
|
Academic Article
|
Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements.
|
Academic Article
|
Reduced Neuroinflammation and Improved Functional Recovery after Traumatic Brain Injury by Prophylactic Diet Supplementation in Mice.
|
Academic Article
|
GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.
|
Academic Article
|
Study on the therapeutic index and synergistic effect of Chitosan-zinc oxide nanomicellar composites for drug-resistant bacterial biofilm inhibition.
|
Academic Article
|
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.
|
Academic Article
|
Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia.
|
Academic Article
|
Cyclic-AMP induces Nogo-A receptor NgR1 internalization and inhibits Nogo-A-mediated collapse of growth cone.
|
Academic Article
|
Key signaling pathways regulate the biological activities and accumulation of amyloid-beta.
|
Academic Article
|
Plant-Based Nutritional Supplementation Attenuates LPS-Induced Low-Grade Systemic Activation.
|
Academic Article
|
Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models.
|
Academic Article
|
Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease.
|
Academic Article
|
Control of ?-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-?/? and Nuclear Factor ?-B.
|
Academic Article
|
Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders.
|