Item Type | Name |
Academic Article
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Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice.
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Academic Article
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Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
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Academic Article
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Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.
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Academic Article
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Adenoviral expression of murine serum amyloid A proteins to study amyloid fibrillogenesis.
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Academic Article
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Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis.
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Academic Article
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Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis.
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Academic Article
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Amyloid formation in the rat: adenoviral expression of mouse serum amyloid A proteins.
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Academic Article
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Expression of mouse acute-phase (SAA1.1) and constitutive (SAA4) serum amyloid A isotypes: influence on lipoprotein profiles.
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Academic Article
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Increased serum amyloid a levels reflect colitis severity and precede amyloid formation in IL-2 knockout mice.
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Academic Article
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Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injury.
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Academic Article
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Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.
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Academic Article
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In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice.
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Academic Article
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A mouse model for serum amyloid A amyloidosis.
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Academic Article
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Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.
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Academic Article
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Abeta deposition is essential to AD neuropathology.
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Academic Article
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Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
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Academic Article
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In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.
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Academic Article
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ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
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Academic Article
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Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.
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Academic Article
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Developmental expression of the Xenopus laevis fos protooncogene.
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Academic Article
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Expression of mouse apolipoprotein SAA1.1 in CE/J mice: isoform-specific effects on amyloidogenesis.
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Academic Article
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JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.
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Academic Article
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High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
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Academic Article
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Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity.
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Academic Article
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Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system.
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Academic Article
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Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.
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Academic Article
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Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor.
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Academic Article
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The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury.
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Academic Article
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Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis.
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Academic Article
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Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice.
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Academic Article
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Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of A?PP transgenic mice.
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Academic Article
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The cysteine protease inhibitor, E64d, reduces brain amyloid-? and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, ?-secretase activity.
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Academic Article
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The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
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Academic Article
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Nanoparticles for targeted delivery of antioxidant enzymes to the brain after cerebral ischemia and reperfusion injury.
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Academic Article
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Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.
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Academic Article
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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
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Academic Article
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Mouse serum amyloid A protein (SAA5) structure and expression.
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Academic Article
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Structure of the mouse Saa4 gene and its linkage to the serum amyloid A gene family.
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Academic Article
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Neprilysin regulates amyloid Beta peptide levels.
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Academic Article
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Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice.
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Academic Article
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Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage.
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Academic Article
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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
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Academic Article
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Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
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Academic Article
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Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death.
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Academic Article
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Complement-dependent P-selectin expression and injury following ischemic stroke.
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Academic Article
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Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors alpha and beta.
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Academic Article
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Neprilysin protects neurons against Abeta peptide toxicity.
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Academic Article
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Semi-allogeneic vaccine for T-cell lymphoma.
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Academic Article
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Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.
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Academic Article
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Delta 2-specific opioid receptor agonist and hibernating woodchuck plasma fraction provide ischemic neuroprotection.
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Academic Article
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Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
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Academic Article
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Motoneuronotrophic factor analog GM6 reduces infarct volume and behavioral deficits following transient ischemia in the mouse.
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Academic Article
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Semi-allogeneic vaccines and tumor-induced immune tolerance.
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Academic Article
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GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
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Academic Article
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Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
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Academic Article
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Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease.
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Academic Article
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Transcranial laser therapy attenuates amyloid-? peptide neuropathology in amyloid-? protein precursor transgenic mice.
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Academic Article
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Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice.
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Academic Article
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Protective effects of incensole acetate on cerebral ischemic injury.
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Academic Article
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Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing A?PP containing the wild-type ?-secretase site sequence.
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Academic Article
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Independent regulation of transcription of the two strands of the c-myc gene.
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Academic Article
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Regulation of c-myc transcription and mRNA abundance by serum growth factors and cell contact.
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Academic Article
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Association of apolipoprotein E with murine amyloid A protein amyloid.
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Academic Article
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Serum amyloid A protein family. Differential induction by oxidized lipids in mouse strains.
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Academic Article
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Structural prerequisites for serum amyloid A fibril formation.
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Academic Article
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Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors.
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Concept
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Mice, Inbred CBA
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Knockout
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Concept
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Mice, Inbred C3H
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Concept
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Mice
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Concept
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Mice, Inbred ICR
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Transgenic
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Mutant Strains
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Academic Article
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The cysteine protease cathepsin B is a key drug target and cysteine protease inhibitors are potential therapeutics for traumatic brain injury.
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Academic Article
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Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
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Academic Article
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Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury.
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Academic Article
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Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement.
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Academic Article
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SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
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Academic Article
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A therapeutic cancer vaccine against GL261 murine glioma.
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Academic Article
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Dietary supplementation of GrandFusion(?) mitigates cerebral ischemia-induced neuronal damage and attenuates inflammation.
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Academic Article
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The Fli-1 transcription factor is a critical regulator for controlling the expression of chemokine C-X-C motif ligand 2 (CXCL2).
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Academic Article
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Non-genomic oestrogen receptor signal in B lymphocytes: An approach towards therapeutic interventions for infection, autoimmunity and cancer.
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Academic Article
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High-Sodium Diet Has Opposing Effects on?Mean Arterial Blood Pressure and?Cerebral Perfusion in a Transgenic Mouse Model of Alzheimer's Disease.
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Academic Article
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The Effect of Diet on Improved Endurance in Male C57BL/6 Mice.
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Academic Article
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Impact of nutrition on inflammation, tauopathy, and behavioral outcomes from chronic traumatic encephalopathy.
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Academic Article
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Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements.
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Academic Article
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Reduced Neuroinflammation and Improved Functional Recovery after Traumatic Brain Injury by Prophylactic Diet Supplementation in Mice.
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Academic Article
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GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.
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Academic Article
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Correction to: GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.
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Academic Article
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Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.
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Academic Article
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Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia.
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Academic Article
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Plant-Based Nutritional Supplementation Attenuates LPS-Induced Low-Grade Systemic Activation.
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Academic Article
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Exogenous Ketone Supplements Improved Motor Performance in Preclinical Rodent Models.
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Academic Article
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Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease.
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Academic Article
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Control of ?-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-?/? and Nuclear Factor ?-B.
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Academic Article
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Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders.
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Academic Article
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Cathepsin B Deficiency Improves Memory Deficits and Reduces Amyloid-? in hA?PP Mouse Models Representing the Major Sporadic Alzheimer's Disease Condition.
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