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Kindy, Mark
One or more keywords matched the following items that are connected to
Kindy, Mark
Item Type
Name
Academic Article
Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.
Academic Article
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
Academic Article
High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
Academic Article
Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.
Academic Article
Effective post-insult neuroprotection by a novel Ca(2+)/ calmodulin-dependent protein kinase II (CaMKII) inhibitor.
Academic Article
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
Academic Article
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation.
Academic Article
Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Academic Article
Neprilysin protects neurons against Abeta peptide toxicity.
Academic Article
Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
Academic Article
Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing A?PP containing the wild-type ?-secretase site sequence.
Concept
Peptide Fragments
Academic Article
Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
Search Criteria
Peptide Fragments