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Kindy, Mark
One or more keywords matched the following items that are connected to Kindy, Mark
Item TypeName
Academic Article Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.
Academic Article Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress.
Academic Article In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice.
Academic Article Abeta deposition is essential to AD neuropathology.
Academic Article Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.
Academic Article Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.
Academic Article Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.
Academic Article Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease.
Academic Article Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics.
Academic Article High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
Academic Article Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner.
Academic Article The cysteine protease inhibitor, E64d, reduces brain amyloid-? and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, ?-secretase activity.
Academic Article Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease.
Academic Article RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.
Academic Article Mouse serum amyloid A protein (SAA5) structure and expression.
Academic Article Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation.
Academic Article Neprilysin regulates amyloid Beta peptide levels.
Academic Article Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Academic Article Neprilysin protects neurons against Abeta peptide toxicity.
Academic Article Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease.
Academic Article Motoneuronotrophic factor analog GM6 reduces infarct volume and behavioral deficits following transient ischemia in the mouse.
Academic Article GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
Academic Article Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
Academic Article A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology.
Academic Article Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce beta-amyloid related to Alzheimer's disease.
Academic Article Transcranial laser therapy attenuates amyloid-? peptide neuropathology in amyloid-? protein precursor transgenic mice.
Academic Article Deletion of the cathepsin B gene improves memory deficits in a transgenic ALZHeimer's disease mouse model expressing A?PP containing the wild-type ?-secretase site sequence.
Concept Peptides
Concept Amyloid beta-Peptides
Academic Article Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic.
Academic Article GM6 Attenuates Alzheimer's Disease Pathology in APP Mice.
Academic Article Key signaling pathways regulate the biological activities and accumulation of amyloid-beta.
Academic Article Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease.
Academic Article Control of ?-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-?/? and Nuclear Factor ?-B.
Academic Article cAMP-induced decrease in cell-surface laminin receptor and cellular prion protein attenuates amyloid-? uptake and amyloid-?-induced neuronal cell death.
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