Item Type | Name |
Academic Article
|
Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
|
Academic Article
|
Regulation of the p58GTA cell division control-related protein kinase during phorbol 12-myristate 13-acetate-induced terminal differentiation of U937 cells.
|
Academic Article
|
In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium.
|
Academic Article
|
Inhibition of caspases by cytokine response modifier A blocks androgen ablation-mediated prostate cancer cell death in vivo.
|
Academic Article
|
Bax-induced apoptotic cell death.
|
Academic Article
|
Treatment of patients with metastatic melanoma with bryostatin-1--a phase II study.
|
Academic Article
|
Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor.
|
Academic Article
|
Phorbol ester treatment of K562 cells regulates the transcriptional activity of AML1c through phosphorylation.
|
Academic Article
|
The role of the Smad3 protein in phorbol ester-induced promoter expression.
|
Academic Article
|
Regulation of RUNX1/AML1 during the G2/M transition.
|
Academic Article
|
Induction of the proto-oncogene c-jun by angiotensin II.
|
Academic Article
|
Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
|
Academic Article
|
PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
|
Academic Article
|
The Pim protein kinases regulate energy metabolism and cell growth.
|
Academic Article
|
Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.
|
Academic Article
|
Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2.
|
Academic Article
|
A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth.
|
Academic Article
|
Phosphorylation of transcription factors.
|
Academic Article
|
Inhibitors of cyclin-dependent kinase and cancer.
|
Academic Article
|
Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C.
|
Academic Article
|
Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation.
|
Academic Article
|
Pim family kinases enhance tumor growth of prostate cancer cells.
|
Academic Article
|
Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
|
Academic Article
|
Differentiation and growth modulation of chronic myelogenous leukemia cells by bryostatin.
|
Academic Article
|
The BH3 mimetic ABT-737 induces cancer cell senescence.
|
Academic Article
|
A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.
|
Academic Article
|
Targeted glycoprotein enrichment and identification in stromal cell secretomes using azido sugar metabolic labeling.
|
Academic Article
|
Stress-activated protein kinases bind directly to the delta domain of c-Jun in resting cells: implications for repression of c-Jun function.
|
Academic Article
|
In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity.
|
Academic Article
|
Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.
|
Concept
|
Kruppel-Like Transcription Factors
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
Concept
|
Genomic Instability
|
Concept
|
Cytokines
|
Concept
|
Angiogenesis Inhibitors
|
Concept
|
Tandem Mass Spectrometry
|
Concept
|
Muscle, Smooth, Vascular
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Benz(a)Anthracenes
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
CDC2-CDC28 Kinases
|
Concept
|
Neutrophils
|
Concept
|
Disease Models, Animal
|
Concept
|
Minocycline
|
Concept
|
DNA Methylation
|
Concept
|
Anti-Bacterial Agents
|
Concept
|
Phorbols
|
Concept
|
Brain Neoplasms
|
Concept
|
Receptors, Somatotropin
|
Concept
|
Methionine
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Benzene Derivatives
|
Concept
|
Receptors, Platelet-Derived Growth Factor
|
Concept
|
Lung Neoplasms
|
Concept
|
RNA, Small Interfering
|
Concept
|
Androgens
|
Concept
|
Kaplan-Meier Estimate
|
Concept
|
Heat-Shock Proteins
|
Concept
|
Epithelioid Cells
|
Concept
|
Interferon-gamma
|
Concept
|
Chemokine CXCL5
|
Concept
|
Receptors, IgG
|
Concept
|
Caspase 9
|
Concept
|
Cell Lineage
|
Concept
|
Niacinamide
|
Concept
|
Phorbol 12,13-Dibutyrate
|
Concept
|
Ultraviolet Rays
|
Concept
|
Mitochondria
|
Concept
|
Lymphoid Enhancer-Binding Factor 1
|
Concept
|
Ecotoxicology
|
Concept
|
Phosphorus Radioisotopes
|
Concept
|
Flow Cytometry
|
Concept
|
Pain
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
Concept
|
Prostatic Neoplasms
|
Concept
|
Proportional Hazards Models
|
Concept
|
Neoplasm Metastasis
|
Concept
|
G-Quadruplexes
|
Concept
|
Mitogen-Activated Protein Kinases
|
Concept
|
Insulin Receptor Substrate Proteins
|
Concept
|
Oncogenes
|
Concept
|
S Phase
|
Concept
|
Cell Division
|
Concept
|
Pleural Effusion
|
Concept
|
Antigens, Differentiation
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
Concept
|
Cross-Over Studies
|
Concept
|
Receptors, Transforming Growth Factor beta
|
Concept
|
Cyclin-Dependent Kinases
|
Concept
|
Tetrahydroisoquinolines
|
Concept
|
COS Cells
|
Concept
|
Oligonucleotide Probes
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Pyrazoles
|
Concept
|
DNA, Complementary
|
Concept
|
Interleukin-15
|
Concept
|
Cadherins
|
Concept
|
Sensitivity and Specificity
|
Concept
|
PAX5 Transcription Factor
|
Concept
|
Receptor, IGF Type 1
|
Concept
|
Telomerase
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Antineoplastic Agents, Alkylating
|
Concept
|
Proto-Oncogenes
|
Concept
|
Leukemia, Myeloid
|
Concept
|
Androgen Antagonists
|
Concept
|
Clinical Trials, Phase I as Topic
|
Concept
|
Treatment Outcome
|
Concept
|
Phenylurea Compounds
|
Concept
|
Suramin
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
Concept
|
Macrophages
|
Concept
|
Thymus Neoplasms
|
Concept
|
Bone Marrow Transplantation
|
Concept
|
Serpins
|
Concept
|
Cricetinae
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 6
|
Concept
|
Macrolides
|
Concept
|
NIH 3T3 Cells
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Amino Acid Substitution
|
Concept
|
Sirolimus
|
Concept
|
Receptors, Transferrin
|
Concept
|
Ubiquitin
|
Concept
|
Protein Phosphatase 2
|
Concept
|
Animals
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
Concept
|
Glial Fibrillary Acidic Protein
|
Concept
|
Binding, Competitive
|
Concept
|
Antigens, CD7
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
Lymphoma, B-Cell
|
Concept
|
Chronic Disease
|
Concept
|
Models, Immunological
|
Concept
|
STAT5 Transcription Factor
|
Concept
|
Ovarian Neoplasms
|
Concept
|
Amino Acid Sequence
|
Concept
|
Disease-Free Survival
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Random Allocation
|
Concept
|
Mice, Knockout
|
Concept
|
Leukemia, Myelomonocytic, Chronic
|
Concept
|
Transforming Growth Factors
|
Concept
|
Cohort Studies
|
Concept
|
Nuclear Envelope
|
Concept
|
Antibodies
|
Concept
|
Growth Hormone
|
Concept
|
Antineoplastic Agents
|
Concept
|
Leukemia
|
Concept
|
Neoplasms, Experimental
|
Concept
|
Myocytes, Cardiac
|
Concept
|
Neoplasms, Nerve Tissue
|
Concept
|
Mice, Inbred C3H
|
Concept
|
Genes, fos
|
Concept
|
Calcium
|
Concept
|
Nose Neoplasms
|
Concept
|
Mitogens
|
Concept
|
Precipitin Tests
|
Concept
|
STAT3 Transcription Factor
|
Concept
|
Blotting, Western
|
Concept
|
Cyclin-Dependent Kinase 2
|
Concept
|
Stomach Neoplasms
|
Concept
|
Bone Neoplasms
|
Concept
|
Fusion Proteins, bcr-abl
|
Concept
|
Thymoma
|
Concept
|
Lipopolysaccharides
|
Concept
|
Transplantation Tolerance
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Carcinoma, Neuroendocrine
|
Concept
|
Enhancer Elements, Genetic
|
Concept
|
Chemokine CXCL2
|
Concept
|
Perivascular Epithelioid Cell Neoplasms
|
Concept
|
Dual Specificity Phosphatase 1
|
Concept
|
Chloramphenicol O-Acetyltransferase
|
Concept
|
Luminescent Measurements
|
Concept
|
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
|
Concept
|
Carcinoma, Bronchogenic
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Prostate-Specific Antigen
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 11
|
Concept
|
Gonadotropin-Releasing Hormone
|
Concept
|
Shc Signaling Adaptor Proteins
|
Concept
|
Infusions, Intravenous
|
Concept
|
Growth Inhibitors
|
Concept
|
Head and Neck Neoplasms
|
Concept
|
Lymphokines
|
Concept
|
Phenylthiohydantoin
|
Concept
|
Caspase 3
|
Concept
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
|
Concept
|
Carcinogens
|
Concept
|
Genes, jun
|
Concept
|
Protein Synthesis Inhibitors
|
Concept
|
Mice
|
Concept
|
Bryostatins
|
Concept
|
CASP8 and FADD-Like Apoptosis Regulating Protein
|
Concept
|
Vascular Endothelial Growth Factors
|
Concept
|
Immunoenzyme Techniques
|
Concept
|
Models, Biological
|
Concept
|
Leukocyte Common Antigens
|
Concept
|
Proto-Oncogene Proteins c-mdm2
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
Concept
|
Adenocarcinoma
|
Concept
|
Proto-Oncogene Proteins c-met
|
Concept
|
Phosphotyrosine
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Melanoma
|
Concept
|
Octamer Transcription Factor-3
|
Concept
|
Lactoferrin
|
Concept
|
Immune Sera
|
Concept
|
Matrix Metalloproteinase 9
|
Concept
|
Aspartic Acid
|
Concept
|
B7-2 Antigen
|
Concept
|
Cerebral Hemorrhage
|
Concept
|
Neoplasm Recurrence, Local
|
Concept
|
Growth Substances
|
Concept
|
Genes, ras
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Methotrexate
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
Concept
|
Retrospective Studies
|
Concept
|
GATA1 Transcription Factor
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Health Policy
|
Concept
|
Melanoma, Experimental
|
Concept
|
Sequence Deletion
|
Concept
|
Phorbol Esters
|
Concept
|
Isoantigens
|
Concept
|
Tyrosine
|
Concept
|
Liver Neoplasms
|
Concept
|
Mice, Transgenic
|
Concept
|
T-Lymphocytes
|
Concept
|
Mitochondria, Heart
|
Concept
|
Soft Tissue Neoplasms
|
Concept
|
Fas-Associated Death Domain Protein
|
Concept
|
Tetradecanoylphorbol Acetate
|
Concept
|
Granulocyte-Macrophage Colony-Stimulating Factor
|
Concept
|
Phosphopyruvate Hydratase
|
Concept
|
Antigens, CD
|
Concept
|
Microtubule-Associated Proteins
|
Concept
|
Epitopes
|
Concept
|
Chickens
|
Concept
|
Neoplasm Invasiveness
|
Concept
|
Injections, Intraperitoneal
|
Concept
|
MAP Kinase Kinase 1
|
Concept
|
Methyl Methanesulfonate
|
Concept
|
Monocytes
|
Concept
|
Mollusca
|
Concept
|
TATA-Box Binding Protein
|
Concept
|
Benzylidene Compounds
|
Concept
|
Annexins
|
Concept
|
Interleukin-2
|
Concept
|
G2 Phase
|
Concept
|
Lactones
|
Concept
|
Tosyl Compounds
|
Concept
|
Ifosfamide
|
Concept
|
Hemangiosarcoma
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
RNA, Messenger
|
Concept
|
Glutathione Transferase
|
Concept
|
Caspase 8
|
Concept
|
Survival Rate
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Humans
|
Concept
|
Multiprotein Complexes
|
Concept
|
Doxorubicin
|
Concept
|
Antigens, Differentiation, T-Lymphocyte
|
Concept
|
Sarcoma
|
Concept
|
Jurkat Cells
|
Concept
|
Transcription Factor TFIIB
|
Concept
|
Prostate
|
Concept
|
Colony-Forming Units Assay
|
Concept
|
Cell Movement
|
Concept
|
Leukemia, T-Cell
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Methods
|
Concept
|
Death Domain Receptor Signaling Adaptor Proteins
|
Concept
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
Drug Screening Assays, Antitumor
|
Concept
|
Hepatocyte Growth Factor
|
Concept
|
Rabbits
|
Concept
|
Liver Cirrhosis
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Intellectual Disability
|
Concept
|
Burkitt Lymphoma
|
Concept
|
Phospholipids
|
Concept
|
Receptors, CXCR4
|
Concept
|
Zinc Fingers
|
Concept
|
Benzenesulfonates
|
Concept
|
Cysteine Proteinase Inhibitors
|
Concept
|
Cerebral Amyloid Angiopathy
|
Concept
|
Fatal Outcome
|
Concept
|
Caspases
|
Concept
|
Inflammation
|
Concept
|
Etoposide
|
Concept
|
Mice, Inbred NOD
|
Concept
|
Bias
|
Concept
|
Saralasin
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Chemokine CCL5
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
Coculture Techniques
|
Concept
|
Tobacco Smoke Pollution
|
Concept
|
Mesocricetus
|
Concept
|
Angiotensin II
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Smad3 Protein
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Protease Inhibitors
|
Concept
|
HL-60 Cells
|
Concept
|
Interleukin-1beta
|
Concept
|
Models, Genetic
|
Concept
|
Chromosomes, Human, Pair 1
|
Concept
|
Meta-Analysis as Topic
|
Concept
|
Response Elements
|
Concept
|
G1 Phase
|
Concept
|
Haplorhini
|
Concept
|
Immunotherapy, Adoptive
|
Concept
|
Insulin-Like Growth Factor II
|
Concept
|
Luciferases
|
Concept
|
Phagocytosis
|
Concept
|
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
|
Concept
|
K562 Cells
|
Concept
|
Carcinoma, Hepatocellular
|
Concept
|
Binding Sites
|
Concept
|
Cyclophosphamide
|
Concept
|
Radiotherapy, Intensity-Modulated
|
Concept
|
Interleukin-8
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Carcinoma, Renal Cell
|
Concept
|
Leukemia, Experimental
|
Concept
|
Lymph Nodes
|
Concept
|
Carcinoma, Squamous Cell
|
Concept
|
Endothelial Growth Factors
|
Concept
|
Depsipeptides
|
Concept
|
Mice, Nude
|
Concept
|
Mice, SCID
|
Concept
|
Peptidylprolyl Isomerase
|
Concept
|
Bromodeoxyuridine
|
Concept
|
Mutagenesis
|
Concept
|
Caenorhabditis elegans Proteins
|
Concept
|
Epidermal Growth Factor
|
Concept
|
Mice, Inbred Strains
|
Concept
|
Genes, myc
|
Concept
|
Chrysenes
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Macrophage-1 Antigen
|
Concept
|
Microfilament Proteins
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Fas Ligand Protein
|
Concept
|
Sulfur Radioisotopes
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
Concept
|
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
|
Concept
|
Kidney Neoplasms
|
Concept
|
3' Untranslated Regions
|
Concept
|
Rats
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
Concept
|
Interleukin-6
|
Concept
|
Receptors, Immunologic
|
Concept
|
Biphenyl Compounds
|
Concept
|
Spleen
|
Concept
|
Oligodeoxyribonucleotides
|
Concept
|
Sequence Homology, Nucleic Acid
|
Concept
|
Mouth Neoplasms
|
Concept
|
Apyrase
|
Concept
|
Models, Molecular
|
Concept
|
Sp1 Transcription Factor
|
Concept
|
Benzamides
|
Concept
|
5'-Nucleotidase
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Mitogen-Activated Protein Kinase 10
|
Concept
|
Myotonic Dystrophy
|
Concept
|
Testosterone
|
Concept
|
Leucine Zippers
|
Concept
|
Breast Neoplasms
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
B-Lymphocytes
|
Concept
|
Nitrophenols
|
Concept
|
Point Mutation
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
Indazoles
|
Concept
|
Adaptor Proteins, Vesicular Transport
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
United States
|
Concept
|
Dual Specificity Phosphatase 2
|
Concept
|
Protein Conformation
|
Concept
|
Polyploidy
|
Concept
|
Off-Label Use
|
Concept
|
Sulfonamides
|
Concept
|
Colony-Stimulating Factors
|
Concept
|
Gene Deletion
|
Concept
|
In Situ Hybridization, Fluorescence
|
Concept
|
Receptors, Tumor Necrosis Factor
|
Concept
|
U937 Cells
|
Concept
|
Mutation, Missense
|
Concept
|
NADPH Oxidases
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
Concept
|
MAP Kinase Kinase 4
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
Deoxycytidine
|
Concept
|
Receptors, TNF-Related Apoptosis-Inducing Ligand
|
Concept
|
Mitogen-Activated Protein Kinase Phosphatases
|
Concept
|
Base Sequence
|
Concept
|
Amino Acid Motifs
|
Concept
|
Follow-Up Studies
|
Concept
|
Killer Cells, Natural
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Carcinoma, Small Cell
|
Concept
|
Immunohistochemistry
|
Concept
|
Colonic Neoplasms
|
Concept
|
Immune Tolerance
|
Concept
|
Injections, Intravenous
|
Concept
|
Milk Proteins
|
Concept
|
Gastrointestinal Neoplasms
|
Concept
|
Immunoblotting
|
Concept
|
TNF-Related Apoptosis-Inducing Ligand
|
Concept
|
Interleukin-3
|
Concept
|
Facial Neoplasms
|
Academic Article
|
Reducing CD73 expression by IL1?-Programmed Th17 cells improves immunotherapeutic control of tumors.
|
Academic Article
|
The 2014 Surgeon General's report: "The health consequences of smoking--50 years of progress": a paradigm shift in cancer care.
|
Academic Article
|
Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
|
Academic Article
|
Pim1 kinase regulates c-Kit gene translation.
|
Academic Article
|
Angiosarcoma treated successfully with anti-PD-1 therapy - a case report.
|
Academic Article
|
Quantitative meta-analytic approaches for the systematic synthesis of data and hazard identification: A case study of decreased pain sensitivity due to trimethylbenzene exposure.
|
Academic Article
|
Corrigendum to "Quantitative meta-analytic approaches to the systematic synthesis of data and hazard identification: A case-study of decreased pain sensitivity due to trimethylbenzene exposure" [Environ. Res. 158C (2017) 598-609].
|
Concept
|
Mechanistic Target of Rapamycin Complex 1
|
Concept
|
Th17 Cells
|
Concept
|
GPI-Linked Proteins
|
Concept
|
Real-Time Polymerase Chain Reaction
|
Concept
|
Programmed Cell Death 1 Receptor
|
Concept
|
Antibodies, Monoclonal, Humanized
|
Concept
|
Proteasome Inhibitors
|
Concept
|
Polycomb Repressive Complex 2
|
Concept
|
Prostatic Neoplasms, Castration-Resistant
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|
Concept
|
Myotonin-Protein Kinase
|
Concept
|
ErbB Receptors
|
Concept
|
Celecoxib
|
Concept
|
Bortezomib
|
Concept
|
Enhancer of Zeste Homolog 2 Protein
|
Concept
|
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
|
Concept
|
Nanog Homeobox Protein
|
Concept
|
Src Homology 2 Domain-Containing, Transforming Protein 1
|
Concept
|
Antineoplastic Agents, Immunological
|
Concept
|
Bcl-2-Like Protein 11
|
Concept
|
NIMA-Interacting Peptidylprolyl Isomerase
|
Concept
|
NADPH Oxidase 4
|
Academic Article
|
Suramin inhibits growth and yet promotes insulin-like growth factor II expression in HepG2 cells.
|