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Kraft, Andrew
One or more keywords matched the following items that are connected to Kraft, Andrew
Item TypeName
Academic Article Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
Academic Article Upstream regions of the c-jun promoter regulate phorbol ester-induced transcription in U937 leukemic cells.
Academic Article Regulation of the p58GTA cell division control-related protein kinase during phorbol 12-myristate 13-acetate-induced terminal differentiation of U937 cells.
Academic Article Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase.
Academic Article Regulation of myeloid cell growth by distinct effectors of Ras.
Academic Article Bax-induced apoptotic cell death.
Academic Article Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.
Academic Article The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Academic Article The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Academic Article Overexpression of the oncogenic kinase Pim-1 leads to genomic instability.
Academic Article Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor.
Academic Article Phorbol ester treatment of K562 cells regulates the transcriptional activity of AML1c through phosphorylation.
Academic Article Regulation of dual-specificity phosphatases M3/6 and hVH5 by phorbol esters. Analysis of a delta-like domain.
Academic Article Combination of gemcitabine antagonizes antitumor activity of paclitaxel through prevention of mitotic arrest and apoptosis.
Academic Article Induction of the proto-oncogene c-jun by angiotensin II.
Academic Article Multiple doses of diacylglycerol and calcium ionophore are necessary to activate AP-1 enhancer activity and induce markers of macrophage differentiation.
Academic Article Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Academic Article Cell cycle dependent antagonistic interactions between paclitaxel and carboplatin in combination therapy.
Academic Article Hypoxia-inducible factor-2alpha regulates the expression of TRAIL receptor DR5 in renal cancer cells.
Academic Article PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article Overexpression of protein kinase C beta 1 is not sufficient to induce factor independence in the interleukin-3-dependent myeloid cell line FDC-P1.
Academic Article The Pim protein kinases regulate energy metabolism and cell growth.
Academic Article Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737.
Academic Article Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer.
Academic Article Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.
Academic Article Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.
Academic Article Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Academic Article Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1.
Academic Article Varied differentiation responses of human leukemias to bryostatin 1.
Academic Article The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Academic Article Signal transduction by a CD16/CD7/Jak2 fusion protein.
Academic Article Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Academic Article Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.
Academic Article A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth.
Academic Article Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells.
Academic Article Phosphorylation of transcription factors.
Academic Article Inhibitors of cyclin-dependent kinase and cancer.
Academic Article Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation.
Academic Article The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells.
Academic Article RAS, MYC, and sensitivity to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis.
Academic Article The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
Academic Article Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association.
Academic Article Pim family kinases enhance tumor growth of prostate cancer cells.
Academic Article ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.
Academic Article Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
Academic Article A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Academic Article p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
Academic Article Regulation of Skp2 levels by the Pim-1 protein kinase.
Academic Article The BH3 mimetic ABT-737 induces cancer cell senescence.
Academic Article Bryostatin induces changes in protein kinase C location and activity without altering c-myc gene expression in human promyelocytic leukemia cells (HL-60).
Academic Article Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor.
Academic Article The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain.
Academic Article In vitro association between the Jun protein family and the general transcription factors, TBP and TFIIB.
Academic Article Stress-activated protein kinases bind directly to the delta domain of c-Jun in resting cells: implications for repression of c-Jun function.
Academic Article A peptide encoding the c-Jun delta domain inhibits the activity of a c-jun amino-terminal protein kinase.
Academic Article Multiple signal transduction pathways mediate c-Jun protein phosphorylation.
Academic Article Regulation of jun/AP-1 oncoproteins by protein phosphorylation.
Academic Article Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leukemic cells.
Academic Article Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.
Academic Article The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.
Concept Oncogenes
Concept Proto-Oncogene Proteins c-pim-1
Concept Proto-Oncogenes
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins c-met
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins c-fos
Concept Proto-Oncogene Proteins
Academic Article Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing.
Academic Article The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling.
Academic Article Induction of differentiation and c-jun expression in human leukemic cells by okadaic acid, an inhibitor of protein phosphatases.
Academic Article Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Academic Article The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.
Academic Article Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
Academic Article Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.
Academic Article Insulin receptor substrate 1 is a substrate of the Pim protein kinases.
Academic Article Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset.
Academic Article PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity.
Academic Article Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.
Academic Article PIM kinase (and Akt) biology and signaling in tumors.
Academic Article PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species.
Academic Article Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.
Academic Article Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
Academic Article Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.
Academic Article PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.
Academic Article PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
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  • Oncogenes