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Kraft, Andrew
One or more keywords matched the following items that are connected to Kraft, Andrew
Item TypeName
Academic Article Complex regulation of CDK2 during phorbol ester-induced hematopoietic differentiation.
Academic Article Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
Academic Article Regulation of the p58GTA cell division control-related protein kinase during phorbol 12-myristate 13-acetate-induced terminal differentiation of U937 cells.
Academic Article Activation of the mitogen-activated protein kinase pathway in U937 leukemic cells induces phosphorylation of the amino terminus of the TATA-binding protein.
Academic Article Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase.
Academic Article In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium.
Academic Article Regulation of myeloid cell growth by distinct effectors of Ras.
Academic Article Conditional expression of mitogen-activated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis.
Academic Article Cytoplasmic domains of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta chain (hbetac) responsible for human GM-CSF-induced myeloid cell differentiation.
Academic Article Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.
Academic Article Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis.
Academic Article The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Academic Article The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Academic Article Overexpression of the oncogenic kinase Pim-1 leads to genomic instability.
Academic Article Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor.
Academic Article Oncogenic Ras sensitizes normal human cells to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis.
Academic Article The role of the Smad3 protein in phorbol ester-induced promoter expression.
Academic Article The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter.
Academic Article Regulation of dual-specificity phosphatases M3/6 and hVH5 by phorbol esters. Analysis of a delta-like domain.
Academic Article Combination of gemcitabine antagonizes antitumor activity of paclitaxel through prevention of mitotic arrest and apoptosis.
Academic Article AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex.
Academic Article Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Academic Article A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
Academic Article PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article Overexpression of protein kinase C beta 1 is not sufficient to induce factor independence in the interleukin-3-dependent myeloid cell line FDC-P1.
Academic Article The Pim protein kinases regulate energy metabolism and cell growth.
Academic Article Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737.
Academic Article Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.
Academic Article Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.
Academic Article Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.
Academic Article Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Academic Article Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1.
Academic Article Varied differentiation responses of human leukemias to bryostatin 1.
Academic Article Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.
Academic Article Signal transduction by a CD16/CD7/Jak2 fusion protein.
Academic Article Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Academic Article Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2.
Academic Article Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.
Academic Article Mapping the intracytoplasmic regions of the alpha granulocyte-macrophage colony-stimulating factor receptor necessary for cell growth regulation.
Academic Article A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth.
Academic Article Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells.
Academic Article Inhibitors of cyclin-dependent kinase and cancer.
Academic Article Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C.
Academic Article The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells.
Academic Article Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells.
Academic Article Pim family kinases enhance tumor growth of prostate cancer cells.
Academic Article Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
Academic Article A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Academic Article p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
Academic Article Regulation of Skp2 levels by the Pim-1 protein kinase.
Academic Article The BH3 mimetic ABT-737 induces cancer cell senescence.
Academic Article Lack of phosphorylation of lipocortin I in A431 epidermoid carcinoma cells treated with phorbol esters.
Academic Article Interleukin-3 and bryostatin 1 mediate rapid nuclear envelope protein phosphorylation in growth factor-dependent FDC-P1 hematopoietic cells. A possible role for nuclear protein kinase C.
Academic Article A phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy.
Academic Article Tyrosine kinase and phosphotyrosine phosphatase activity in human promyelocytic leukemia cells and human polymorphonuclear leukocytes.
Academic Article Bryostatin induces changes in protein kinase C location and activity without altering c-myc gene expression in human promyelocytic leukemia cells (HL-60).
Academic Article Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60.
Academic Article Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor.
Academic Article The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain.
Academic Article Stress-activated protein kinases bind directly to the delta domain of c-Jun in resting cells: implications for repression of c-Jun function.
Academic Article A peptide encoding the c-Jun delta domain inhibits the activity of a c-jun amino-terminal protein kinase.
Academic Article Multiple signal transduction pathways mediate c-Jun protein phosphorylation.
Academic Article Regulation of jun/AP-1 oncoproteins by protein phosphorylation.
Academic Article In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity.
Academic Article The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells.
Academic Article Constitutively active MAP kinase kinase (MEK1) stimulates SAP kinase and c-Jun transcriptional activity in U937 human leukemic cells.
Academic Article Biological activity of 26-succinylbryostatin 1.
Academic Article Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.
Academic Article Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases.
Academic Article The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.
Concept Protein-Tyrosine Kinases
Concept CDC2-CDC28 Kinases
Concept I-kappa B Kinase
Concept Mitogen-Activated Protein Kinases
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept S-Phase Kinase-Associated Proteins
Concept p38 Mitogen-Activated Protein Kinases
Concept Cyclin-Dependent Kinases
Concept Mitogen-Activated Protein Kinase Kinases
Concept Protein Kinase Inhibitors
Concept Ribosomal Protein S6 Kinases
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Mitogen-Activated Protein Kinase 1
Concept CDC2 Protein Kinase
Concept Protein Kinases
Concept Cyclin-Dependent Kinase 2
Concept Mitogen-Activated Protein Kinase 3
Concept MAP Kinase Kinase 1
Concept MAP Kinase Signaling System
Concept Protein Kinase C
Concept Receptor Protein-Tyrosine Kinases
Concept Extracellular Signal-Regulated MAP Kinases
Concept JNK Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase 10
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Janus Kinase 2
Concept MAP Kinase Kinase 4
Concept Phosphatidylinositol 3-Kinases
Concept Mitogen-Activated Protein Kinase Phosphatases
Academic Article Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing.
Academic Article The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling.
Academic Article Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Academic Article The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.
Academic Article Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
Academic Article Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.
Academic Article Insulin receptor substrate 1 is a substrate of the Pim protein kinases.
Academic Article Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset.
Academic Article PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity.
Academic Article Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.
Academic Article PIM kinase (and Akt) biology and signaling in tumors.
Academic Article PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species.
Academic Article Pim1 kinase regulates c-Kit gene translation.
Academic Article Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.
Academic Article Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
Academic Article PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.
Academic Article PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
Concept TOR Serine-Threonine Kinases
Concept Checkpoint Kinase 2
Concept Myotonin-Protein Kinase
Academic Article Synthesis of 2-Oxoquinoline Derivatives as Dual Pim and mTORC Protein Kinase Inhibitors.
Academic Article An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
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