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overview Hainan Lang, M.D, Ph.D. engages in basic hearing research focused on molecular mechanisms of auditory nerve function and repair, myelin degeneration and cochlear macrophage dysfunction in presbyacusis, and auditory impairments in autism spectrum disorders. Working with collaborators within and outside MUSC, our research projects utilize a multidisciplinary approach including cell and molecular biology, auditory electrophysiology, complex mouse behavioral analyses, cochlear gene therapy, and the comparisons of the cochlear pathology between mouse models and postmortem human temporal bones.
One or more keywords matched the following items that are connected to Lang, Hainan
Item TypeName
Academic Article Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury.
Academic Article Sox2 up-regulation and glial cell proliferation following degeneration of spiral ganglion neurons in the adult mouse inner ear.
Academic Article Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear.
Academic Article Role of stromal cell-derived factor-1 expression in the injured mouse auditory nerve.
Academic Article Age-related changes of myelin basic protein in mouse and human auditory nerve.
Academic Article Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss.
Concept Hearing
Concept Hearing Loss, Conductive
Concept Hearing Loss, Central
Concept Hearing Loss, Noise-Induced
Concept Hearing Loss
Concept Hearing Loss, Sensorineural
Academic Article Heptanol application to the mouse round window: a model for studying cochlear lateral wall regeneration.
Academic Article Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve.
Academic Article Noise-Induced Dysregulation of Quaking RNA Binding Proteins Contributes to Auditory Nerve Demyelination and Hearing Loss.
Academic Article Translational and interdisciplinary insights into presbyacusis: A multidimensional disease.
Academic Article Cochlear Immune Response in Presbyacusis: a Focus on Dysregulation of Macrophage Activity.
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  • Hearing