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Lang, Hainan
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overview Hainan Lang, M.D, Ph.D. engages in basic hearing research focused on molecular mechanisms of auditory nerve function and repair, myelin degeneration and cochlear macrophage dysfunction in presbyacusis, and auditory impairments in autism spectrum disorders. Working with collaborators within and outside MUSC, our research projects utilize a multidisciplinary approach including cell and molecular biology, auditory electrophysiology, complex mouse behavioral analyses, cochlear gene therapy, and the comparisons of the cochlear pathology between mouse models and postmortem human temporal bones.
One or more keywords matched the following items that are connected to Lang, Hainan
Item TypeName
Academic Article Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury.
Academic Article Unmyelinated auditory type I spiral ganglion neurons in congenic Ly5.1 mice.
Academic Article Sox2 up-regulation and glial cell proliferation following degeneration of spiral ganglion neurons in the adult mouse inner ear.
Academic Article Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear.
Academic Article Role of stromal cell-derived factor-1 expression in the injured mouse auditory nerve.
Academic Article Age-related changes of myelin basic protein in mouse and human auditory nerve.
Academic Article Analysis of miR-376 RNA cluster members in the mouse inner ear.
Academic Article Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage.
Academic Article Contribution of bone marrow hematopoietic stem cells to adult mouse inner ear: mesenchymal cells and fibrocytes.
Academic Article Nuclear factor kappaB deficiency is associated with auditory nerve degeneration and increased noise-induced hearing loss.
Concept Mice, Inbred CBA
Concept Mice, Knockout
Concept Mice, Quaking
Concept Mice
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mice, Congenic
Concept Mice, Inbred Strains
Academic Article Ouabain-induced cochlear nerve degeneration: synaptic loss and plasticity in a mouse model of auditory neuropathy.
Academic Article Heptanol application to the mouse round window: a model for studying cochlear lateral wall regeneration.
Academic Article Sox10 expressing cells in the lateral wall of the aged mouse and human cochlea.
Academic Article Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve.
Academic Article Contributions of Mouse and Human Hematopoietic Cells to Remodeling of the Adult Auditory Nerve After Neuron Loss.
Academic Article The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration.
Academic Article Macrophage-Mediated Glial Cell Elimination in the Postnatal Mouse Cochlea.
Academic Article Noise-Induced Dysregulation of Quaking RNA Binding Proteins Contributes to Auditory Nerve Demyelination and Hearing Loss.
Academic Article Age-dependent alterations of Kir4.1 expression in neural crest-derived cells of the mouse and human cochlea.
Academic Article A multi-metric approach to characterizing mouse peripheral auditory nerve function using the auditory brainstem response.
Academic Article Cochlear Immune Response in Presbyacusis: a Focus on Dysregulation of Macrophage Activity.
Academic Article Two distinct types of nodes of Ranvier support auditory nerve function in the mouse cochlea.
Academic Article Age-related central gain with degraded neural synchrony in the auditory brainstem of mice and humans.
Academic Article Peripheral Auditory Nerve Impairment in a Mouse Model of Syndromic Autism.
Academic Article The Stria Vascularis in Mice and Humans Is an Early Site of Age-Related Cochlear Degeneration, Macrophage Dysfunction, and Inflammation.
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  • Mice