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One or more keywords matched the following properties of Lopez, Marcelo
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overview Dr. Lopez's research interests are the effect of stress and other environmental factors on alcohol intake and relapse, and the role of learning in the development of addictive behaviors. He is conducting studies to evaluate the effect of stress at different developmental stages on voluntary alcohol intake. Dr. Lopez conducts behavioral pharmacology studies utilizing numerous rodent models of alcohol exposure. This includes studying alcohol dependence and relapse drinking involving a mouse model of chronic intermittent ethanol (CIE) exposure that produces escalation of drinking. This model that has been used to characterize genetic, neurobiological, and behavioral (motivational) factors that influence alcohol self-administration including measures of relapse, tolerance, and behavioral flexibility.
One or more keywords matched the following items that are connected to Lopez, Marcelo
Item TypeName
Academic Article Alcohol withdrawal and conditioning.
Academic Article Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens.
Academic Article Intensity and duration of chronic ethanol exposure is critical for subsequent escalation of voluntary ethanol drinking in mice.
Academic Article Chronic social isolation and chronic variable stress during early development induce later elevated ethanol intake in adult C57BL/6J mice.
Academic Article Development of ethanol withdrawal-related sensitization and relapse drinking in mice selected for high- or low-ethanol preference.
Academic Article Effects of stress on alcohol drinking: a review of animal studies.
Academic Article Repeated cycles of chronic intermittent ethanol exposure leads to the development of tolerance to aversive effects of ethanol in C57BL/6J mice.
Academic Article Effects of alcohol dependence and withdrawal on stress responsiveness and alcohol consumption.
Academic Article Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice.
Academic Article Effect of pattern and number of chronic ethanol exposures on subsequent voluntary ethanol intake in C57BL/6J mice.
Academic Article Similar ethanol drinking in adolescent and adult C57BL/6J mice after chronic ethanol exposure and withdrawal.
Concept Alcohol Drinking
Concept Drinking Behavior
Academic Article Operant ethanol self-administration in ethanol dependent mice.
Academic Article Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.
Academic Article Repeated episodes of chronic intermittent ethanol promote insensitivity to devaluation of the reinforcing effect of ethanol.
Academic Article Differential potassium channel gene regulation in BXD mice reveals novel targets for pharmacogenetic therapies to reduce heavy alcohol drinking.
Academic Article Forced swim stress increases ethanol consumption in C57BL/6J mice with a history of chronic intermittent ethanol exposure.
Academic Article The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice.
Academic Article Effect of different stressors on voluntary ethanol intake in ethanol-dependent and nondependent C57BL/6J mice.
Academic Article Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption.
Academic Article Impact of social isolation and enriched environment during adolescence on voluntary ethanol intake and anxiety in C57BL/6J mice.
Academic Article Novel anticonvulsants for reducing alcohol consumption: A review of evidence from preclinical rodent drinking models.
Academic Article Neonatal responsiveness to alcohol odor and infant alcohol intake as a function of alcohol experience during late gestation.
Academic Article The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence.
Academic Article Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens.
Academic Article Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains.
Academic Article Variable effects of chronic intermittent ethanol exposure on ethanol drinking in a genetically diverse mouse cohort.
Academic Article The allostatic impact of chronic ethanol on gene expression: A genetic analysis of chronic intermittent ethanol treatment in the BXD cohort.
Academic Article Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward.
Academic Article Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice.
Academic Article Cross-species molecular dissection across alcohol behavioral domains.
Academic Article Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice.
Academic Article Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress.
Academic Article Dynamic c-Fos changes in mouse brain during acute and protracted withdrawal from chronic intermittent ethanol exposure and relapse drinking.
Academic Article Kappa opioid receptors in the bed nucleus of the stria terminalis regulate binge-like alcohol consumption in male and female mice.
Academic Article The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits.
Academic Article Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Academic Article Bioinformatics identification and pharmacological validation of Kcnn3/KCa2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice.
Academic Article The histone methyltransferase G9a mediates stress-regulated alcohol drinking.
Academic Article Transcriptome Analysis of Alcohol Drinking in Non-Dependent and Dependent Mice Following Repeated Cycles of Forced Swim Stress Exposure.
Academic Article Brain regional gene expression network analysis identifies unique interactions between chronic ethanol exposure and consumption.
Concept Binge Drinking
Academic Article Activation of hypothalamic oxytocin neurons reduces binge-like alcohol drinking through signaling at central oxytocin receptors.
Academic Article Dynorphin/Kappa Opioid Receptor Activity Within the Extended Amygdala Contributes to Stress-Enhanced Alcohol Drinking in Mice.
Academic Article Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges.
Academic Article Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice.
Academic Article Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
Academic Article Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder.
Search Criteria
  • Drinking