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Luttrell, Deirdre

One or more keywords matched the following properties of Luttrell, Deirdre

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overview	Deirdre K. Luttrell, Ph.D. is an Assistant Professor in the Divison of Nephrology at the Medical University of South Carolina in Charleston, S.C. Dr. Luttrell earned her Bachelor of Arts degree in Zoology from Pomona College in 1979 and her AM in Zoology from Duke University in 1982. Her doctorate in Microbiology was awarded in 1989 for work done on the role of the c-src proto-oncogene in signal transduction in the laboratory of Dr. Sarah Parsons at the University of Virginia. She worked in drug discovery at GlaxoSmithKline from 1989-2004, where she served as project leader on the discovery of Votrient, A VEGFR2 tyrosine kinase inhibitor. Dr. Luttrell joined MUSC in 2004, where her research focuses on GPCR transactivation of receptor tyrosine kinases.

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overview

Deirdre K. Luttrell, Ph.D. is an Assistant Professor in the Divison of Nephrology at the Medical University of South Carolina in Charleston, S.C. Dr. Luttrell earned her Bachelor of Arts degree in Zoology from Pomona College in 1979 and her AM in Zoology from Duke University in 1982. Her doctorate in Microbiology was awarded in 1989 for work done on the role of the c-src proto-oncogene in signal transduction in the laboratory of Dr. Sarah Parsons at the University of Virginia. She worked in drug discovery at GlaxoSmithKline from 1989-2004, where she served as project leader on the discovery of Votrient, A VEGFR2 tyrosine kinase inhibitor. Dr. Luttrell joined MUSC in 2004, where her research focuses on GPCR transactivation of receptor tyrosine kinases.

One or more keywords matched the following items that are connected to Luttrell, Deirdre

Item Type	Name
Academic Article	Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models.
Academic Article	Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.
Academic Article	Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.
Academic Article	Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation.
Academic Article	Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.
Academic Article	Involvement of pp60c-src with two major signaling pathways in human breast cancer.
Academic Article	Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.
Concept	Protein-Tyrosine Kinases
Concept	Tyrosine
Concept	Receptor Protein-Tyrosine Kinases

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