Item Type | Name |
Academic Article
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Regulation of mitogen-activated protein kinase pathways by catecholamine receptors.
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Academic Article
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G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors.
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Academic Article
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Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.
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Academic Article
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G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases.
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Academic Article
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Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase.
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Academic Article
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Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy.
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Academic Article
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.
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Academic Article
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The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism.
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Academic Article
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Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor.
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Academic Article
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Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors.
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Academic Article
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The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor.
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Academic Article
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Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding.
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Academic Article
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A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes.
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Academic Article
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G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells.
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Academic Article
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beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation.
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Academic Article
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Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.
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Academic Article
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Big G, little G: G proteins and actin cytoskeletal reorganization.
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Academic Article
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Regulation of tyrosine kinase cascades by G-protein-coupled receptors.
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Academic Article
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Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates beta-1 adrenergic receptor endocytosis through different pathways.
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Academic Article
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Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo.
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Academic Article
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Not so strange bedfellows: G-protein-coupled receptors and Src family kinases.
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Academic Article
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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.
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Academic Article
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Transmembrane signaling by G protein-coupled receptors.
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Academic Article
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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades.
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Academic Article
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Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation.
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Academic Article
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Heptahelical terpsichory. Who calls the tune?
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Academic Article
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beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport.
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Academic Article
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The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals.
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Academic Article
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Angiotensin II-induced cyclooxygenase 2 expression in rat aorta vascular smooth muscle cells does not require heterotrimeric G protein activation.
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Academic Article
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A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.
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Academic Article
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Beyond desensitization: physiological relevance of arrestin-dependent signaling.
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Academic Article
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Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity.
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Academic Article
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Emergent biological properties of arrestin pathway-selective biased agonism.
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Academic Article
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The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.
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Academic Article
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'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors.
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Academic Article
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The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
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Academic Article
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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.
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Academic Article
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Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation.
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Academic Article
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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.
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Academic Article
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Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.
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Academic Article
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Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
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Academic Article
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Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.
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Academic Article
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Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors.
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Academic Article
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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases.
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Academic Article
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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation.
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Academic Article
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Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase.
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Academic Article
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Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription.
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Academic Article
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Diversity in arrestin function.
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Academic Article
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane.
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Academic Article
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The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network.
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Academic Article
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A high-content, live-cell, and real-time approach to the quantitation of ligand-induced ?-Arrestin2 and Class A/Class B GPCR mobilization.
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Academic Article
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G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor.
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Academic Article
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Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
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Academic Article
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Mitogenic signaling via G protein-coupled receptors.
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Concept
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Protein Binding
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Concept
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DNA-Binding Proteins
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Concept
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GTP-Binding Protein alpha Subunits, Gi-Go
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Concept
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Heterotrimeric GTP-Binding Proteins
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Concept
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rho GTP-Binding Proteins
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Concept
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GTP-Binding Proteins
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Concept
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GTP-Binding Protein alpha Subunits, Gq-G11
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Concept
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Carrier Proteins
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Concept
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GTP-Binding Protein alpha Subunits, Gs
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Concept
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Monosaccharide Transport Proteins
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Concept
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GTP-Binding Protein Regulators
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Concept
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RNA-Binding Proteins
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Academic Article
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Arrestin-dependent activation of ERK and Src family kinases.
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Academic Article
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Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
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