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Misra, Suniti
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overview Dr. Suniti’s research is in the area of proteoglycan and hyaluronan-CD44 cell signaling and her laboratory focuses on the role of hyaluronan matrices in inflammatory pathologies and cancer. Specifically, she is examining the hyaluronan interactions with variants of cell surface receptors in promoting fibroblasts to myofibroblast phenotypes and their involvement in regulating inflammatory processes.
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Academic Article Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway.
Academic Article Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.
Academic Article Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2.
Academic Article Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus.
Academic Article Hyaluronan, CD44, and cyclooxygenase-2 in colon cancer.
Academic Article Tissue-specific shRNA delivery: a novel approach for gene therapy in cancer.
Academic Article Hyaluronan oligosaccharides as a potential anticancer therapeutic.
Academic Article Delivery of CD44 shRNA/nanoparticles within cancer cells: perturbation of hyaluronan/CD44v6 interactions and reduction in adenoma growth in Apc Min/+ MICE.
Academic Article Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.
Academic Article Regulation of multidrug resistance in cancer cells by hyaluronan.
Academic Article Emmprin promotes anchorage-independent growth in human mammary carcinoma cells by stimulating hyaluronan production.
Academic Article Hyaluronan: a critical component of epithelial-mesenchymal and epithelial-carcinoma transitions.
Academic Article Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells.
Academic Article Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells.
Academic Article Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor.
Academic Article Hyaluronan-CD44 interactions as potential targets for cancer therapy.
Concept Hyaluronan Receptors
Concept Hyaluronic Acid
Academic Article Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-?1 signaling in interstitial lung disease.
Academic Article Periostin induces intracellular cross-talk between kinases and hyaluronan in atrioventricular valvulogenesis.
Academic Article Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer.
Academic Article Roles and targeting of the HAS/hyaluronan/CD44 molecular system in cancer.
Academic Article Transforming growth factor ?1 (TGF?1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis.
Academic Article Transforming growth factor ?1 (TGF?1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.
Academic Article FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells.
Concept Hyaluronan Synthases
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  • Hyaluronic Acid