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Rubinstein, Mark
One or more keywords matched the following items that are connected to Rubinstein, Mark
Item TypeName
Academic Article Antiviral CD4+ memory T cells are IL-15 dependent.
Academic Article The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.
Academic Article Soluble IL-15/IL-15Ra complexes in human serum.
Academic Article Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor aSu/Fc fusion complex in syngeneic murine models of multiple myeloma.
Academic Article Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}.
Academic Article An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
Academic Article Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Academic Article IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Academic Article Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.
Concept Interleukin-15 Receptor alpha Subunit
Concept Interleukin-15
Concept Receptors, Interleukin-15
Academic Article IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Academic Article Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent.
Academic Article Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
Academic Article A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses.
Academic Article Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Academic Article ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
Academic Article Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Academic Article Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Ra Complexes Enhances Tumor Control.
Academic Article Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.
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  • Interleukin 15