| Item Type | Name |
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Academic Article
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Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine.
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Academic Article
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Antiviral CD4+ memory T cells are IL-15 dependent.
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Academic Article
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The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.
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Academic Article
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Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.
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Academic Article
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Soluble IL-15/IL-15Ra complexes in human serum.
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Academic Article
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Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2).
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Academic Article
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Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor aSu/Fc fusion complex in syngeneic murine models of multiple myeloma.
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Academic Article
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Selective stimulation of T cell subsets with antibody-cytokine immune complexes.
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Academic Article
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Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}.
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Academic Article
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Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.
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Academic Article
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Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells.
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Academic Article
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An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
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Academic Article
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Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
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Academic Article
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IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
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Academic Article
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Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.
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Concept
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Interleukin-2 Receptor alpha Subunit
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Concept
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Interleukin-15 Receptor alpha Subunit
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Concept
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Interleukin-15
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Concept
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Receptors, Interleukin-2
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Concept
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Interleukin-12 Subunit p35
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Concept
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Interleukin-7
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Concept
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Receptors, Interleukin-15
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Concept
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Interleukin-2
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Concept
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Interleukin-2 Receptor beta Subunit
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Concept
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Receptors, Interleukin-7
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Concept
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Receptors, Interleukin-12
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Concept
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Interleukin-17
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Concept
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Interleukin-4
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Concept
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Interleukin Receptor Common gamma Subunit
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Concept
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Interleukin-6
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Concept
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Receptors, Interleukin
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Concept
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Interleukin-12
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Academic Article
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IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells.
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Academic Article
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Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
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Academic Article
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The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
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Academic Article
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Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling.
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Academic Article
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Harnessing the IL-7/IL-7Ra axis to improve tumor immunotherapy.
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Academic Article
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Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.
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Academic Article
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IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
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Academic Article
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Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent.
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Academic Article
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Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
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Academic Article
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A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses.
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Academic Article
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Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
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Academic Article
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IL-2 and Beyond in Cancer Immunotherapy.
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Academic Article
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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
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Academic Article
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Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
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Academic Article
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Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Ra Complexes Enhances Tumor Control.
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Academic Article
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IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.
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Academic Article
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Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.
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