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One or more keywords matched the following items that are connected to Rubinstein, Mark
Item TypeName
Academic Article Paracrine release of IL-12 stimulates IFN-gamma production and dramatically enhances the antigen-specific T cell response after vaccination with a novel peptide-based cancer vaccine.
Academic Article Antiviral CD4+ memory T cells are IL-15 dependent.
Academic Article The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.
Academic Article Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.
Academic Article Soluble IL-15/IL-15Ra complexes in human serum.
Academic Article Mechanisms of enhanced antigen-specific T cell response following vaccination with a novel peptide-based cancer vaccine and systemic interleukin-2 (IL-2).
Academic Article Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor aSu/Fc fusion complex in syngeneic murine models of multiple myeloma.
Academic Article Selective stimulation of T cell subsets with antibody-cytokine immune complexes.
Academic Article Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}.
Academic Article Review: novel nonviral delivery approaches for interleukin-12 protein and gene systems: curbing toxicity and enhancing adjuvant activity.
Academic Article Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells.
Academic Article An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.
Academic Article Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells.
Academic Article IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Academic Article Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.
Concept Interleukin-2 Receptor alpha Subunit
Concept Interleukin-15 Receptor alpha Subunit
Concept Interleukin-15
Concept Receptors, Interleukin-2
Concept Interleukin-12 Subunit p35
Concept Interleukin-7
Concept Receptors, Interleukin-15
Concept Interleukin-2
Concept Interleukin-2 Receptor beta Subunit
Concept Receptors, Interleukin-7
Concept Receptors, Interleukin-12
Concept Interleukin-17
Concept Interleukin-4
Concept Interleukin Receptor Common gamma Subunit
Concept Interleukin-6
Concept Receptors, Interleukin
Concept Interleukin-12
Academic Article IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells.
Academic Article Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Academic Article The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
Academic Article Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling.
Academic Article Harnessing the IL-7/IL-7Ra axis to improve tumor immunotherapy.
Academic Article Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.
Academic Article IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Academic Article Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent.
Academic Article Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
Academic Article A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses.
Academic Article Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Academic Article IL-2 and Beyond in Cancer Immunotherapy.
Academic Article ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
Academic Article Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Academic Article Anti-CTLA-4 Activates Intratumoral NK Cells and Combined with IL15/IL15Ra Complexes Enhances Tumor Control.
Academic Article IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.
Academic Article Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.
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  • Interleukin 6