| Item Type | Name |
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Academic Article
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ERAB contains a putative noncleavable signal peptide.
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Academic Article
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Characterization of recombinant, soluble beta-secretase from an insect cell expression system.
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Academic Article
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Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.
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Academic Article
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Role of DNA dynamics in Alzheimer's disease.
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Academic Article
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Molecular toxicity of aluminium in relation to neurodegeneration.
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Academic Article
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Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, Luigi Puglielli.
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Academic Article
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Frontiers in the pathogenesis of Alzheimer's disease.
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Academic Article
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APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity.
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Academic Article
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Major carboxyl terminal fragments generated by ?-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long.
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Academic Article
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Gene structure and organization of the human beta-secretase (BACE) promoter.
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Academic Article
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Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression.
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Academic Article
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Differential expression of cholesterol hydroxylases in Alzheimer's disease.
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Academic Article
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Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors.
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Academic Article
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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
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Academic Article
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Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region.
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Academic Article
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Differential accumulation of secreted AbetaPP metabolites in ocular fluids.
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Academic Article
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Human retinal pigment epithelium cells as functional models for the RPE in vivo.
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Academic Article
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Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model.
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Concept
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Thalidomide
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Concept
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Cytokines
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Aluminum
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Concept
|
Enzyme-Linked Immunosorbent Assay
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Concept
|
Disease Models, Animal
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Concept
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Incretins
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Concept
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Retinal Pigment Epithelium
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Concept
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Spain
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Concept
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Brain Neoplasms
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Concept
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Methionine
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Concept
|
Amyloid beta-Protein Precursor
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Concept
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Hydroxycholesterols
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Concept
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Prefrontal Cortex
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Concept
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Receptors, LDL
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Concept
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Heat-Shock Proteins
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Concept
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ADAM Proteins
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Concept
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Androstadienes
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Concept
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Mitochondria
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Concept
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Microscopy, Video
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Concept
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Incidence
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Concept
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Introns
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Concept
|
Apolipoproteins E
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Concept
|
Rats, Inbred Strains
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Concept
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Mutagens
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Concept
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Drug Design
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Concept
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Magnetic Resonance Imaging
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Concept
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Phosphoinositide Phospholipase C
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Concept
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Trisomy
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Concept
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Receptors, Dopamine
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Concept
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Drosophila melanogaster
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Concept
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Parasympathomimetics
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Concept
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Membrane Potentials
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Concept
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Autolysis
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Concept
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Dietary Fats
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Concept
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Fluorescent Dyes
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Concept
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Cholinesterase Inhibitors
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Concept
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Mice, Inbred BALB C
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Concept
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DNA, Complementary
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Concept
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Fluorescent Antibody Technique
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Concept
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L-Lactate Dehydrogenase
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Concept
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Memory, Short-Term
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Concept
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Polyethylene Glycols
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Concept
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Learning
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Concept
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Pituitary Gland
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Concept
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Receptors, Cell Surface
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Concept
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Aflatoxin B1
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Concept
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Mannose
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Concept
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Dependovirus
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Concept
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Treatment Outcome
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Concept
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Avitaminosis
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Concept
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Tretinoin
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Concept
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Serpins
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Concept
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Cricetinae
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Concept
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N-Methylaspartate
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Concept
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Physostigmine
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Concept
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Lysosomes
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Concept
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Molecular Biology
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Concept
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Aflatoxins
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Concept
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Amino Acid Substitution
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Concept
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Animals
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Concept
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Tartrates
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Concept
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Neurodegenerative Diseases
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Concept
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Double-Blind Method
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Concept
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Amino Acid Sequence
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Concept
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Choline O-Acetyltransferase
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Concept
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Chloroquine
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Concept
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Mice, Knockout
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Concept
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Immunosuppressive Agents
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Concept
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Rodentia
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Concept
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Hydroxamic Acids
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Concept
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Receptors, Lipoprotein
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Concept
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Oxidative Phosphorylation
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Concept
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Cholesterol, LDL
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Concept
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Antineoplastic Agents
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Concept
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Mice, Inbred C3H
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Concept
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Shock
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Concept
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Inositol
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Concept
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Intracellular Membranes
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Concept
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Precipitin Tests
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Concept
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Blotting, Western
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Concept
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Tumor Necrosis Factor Decoy Receptors
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Concept
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T-Lymphocytes, Regulatory
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Concept
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Iodine Radioisotopes
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Concept
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Neuroprotective Agents
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Concept
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Vascular Endothelial Growth Factor Receptor-2
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Concept
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Cricetulus
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Concept
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Longevity
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Concept
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T-Lymphocyte Subsets
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Concept
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Receptors, Lipoxin
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Concept
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Poly A
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Concept
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Glioma
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Concept
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Membrane Microdomains
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Concept
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Dose-Response Relationship, Drug
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Concept
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Leupeptins
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Concept
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Iron
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Concept
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Amyloid
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Concept
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Caspase 3
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Concept
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Protein Synthesis Inhibitors
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Concept
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Mice
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Concept
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Protective Agents
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Concept
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Macular Degeneration
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Concept
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Clinical Trials as Topic
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Concept
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DNA Primers
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Concept
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tau Proteins
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Concept
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Models, Biological
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Concept
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Histocytochemistry
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Concept
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Linear Models
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Concept
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Receptors, Tumor Necrosis Factor, Type II
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Concept
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Cell Adhesion Molecules, Neuron-Glia
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Concept
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Lipoxygenase
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Concept
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Receptors, Muscarinic
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Phosphatidylinositol Diacylglycerol-Lyase
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Concept
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Eye
|
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Concept
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Estrogens
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Concept
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Cerebral Cortex
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Concept
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5' Flanking Region
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Concept
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Glucosamine
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Concept
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Mice, Inbred C57BL
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Concept
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Cholesterol, Dietary
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Concept
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Presenilin-2
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Concept
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Retrospective Studies
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Cytoprotection
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Concept
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Maze Learning
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Chromosomes, Mammalian
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Concept
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Sequence Deletion
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Concept
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Consensus Sequence
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Concept
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Phorbol Esters
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Concept
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Mice, Transgenic
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Concept
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Receptors, Nicotinic
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Concept
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Receptors, Formyl Peptide
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Concept
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Tetradecanoylphorbol Acetate
|
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Concept
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Manganese
|
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Concept
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Postmenopause
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Concept
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Neoplasm Invasiveness
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|
Concept
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Neuroblastoma
|
|
Concept
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Drosophila
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Concept
|
Nucleic Acid Conformation
|
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Concept
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Severity of Illness Index
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Lovastatin
|
|
Concept
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MAP Kinase Signaling System
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Concept
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Humans
|
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Concept
|
Nerve Degeneration
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Concept
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Hearing Loss
|
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Concept
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Hot Temperature
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Concept
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Cattle
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Concept
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Membrane Glycoproteins
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Concept
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DNA, Viral
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Concept
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Hyperlipoproteinemia Type II
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Concept
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Memory Disorders
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Concept
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Receptors, Dopamine D2
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Concept
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Doxycycline
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Concept
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Rabbits
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Concept
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Protein Structure, Tertiary
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Concept
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Nerve Growth Factor
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Concept
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Cholesterol, HDL
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Concept
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Estradiol
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Concept
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5' Untranslated Regions
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Concept
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Inhibitory Concentration 50
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Concept
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Silver Staining
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Concept
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Uridine Diphosphate N-Acetylglucosamine
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Concept
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Psychomotor Performance
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Concept
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Caspases
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Concept
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Inflammation
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Concept
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Odorants
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Concept
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Chromosomes, Human, Pair 11
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Concept
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Receptors, Glucagon
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Concept
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Down Syndrome
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Concept
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Antibodies, Monoclonal
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Concept
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Cholinergic Fibers
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Concept
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Magnesium
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Concept
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Detergents
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Concept
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Neurofibrillary Tangles
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Concept
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Analysis of Variance
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Concept
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Reverse Transcriptase Polymerase Chain Reaction
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Concept
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Protease Inhibitors
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Concept
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Cystathionine beta-Synthase
|
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Concept
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Interleukin-1beta
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Concept
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Cell Culture Techniques
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Concept
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Nerve Growth Factors
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Concept
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Models, Genetic
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Concept
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Response Elements
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Concept
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Antioxidants
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Concept
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Amyloidosis
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Concept
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Alzheimer Disease
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Concept
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Glycosylphosphatidylinositols
|
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Concept
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Immunoglobulin Isotypes
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Concept
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Electrophoretic Mobility Shift Assay
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Concept
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K562 Cells
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Concept
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Binding Sites
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Concept
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Apolipoproteins
|
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Concept
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Rats, Inbred F344
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Concept
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Lymph Nodes
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Concept
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Carbohydrate Sequence
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Concept
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Orientation
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Concept
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Case-Control Studies
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Concept
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Mutagenesis
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Concept
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Mice, Inbred Strains
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Concept
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Extracellular Signal-Regulated MAP Kinases
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Concept
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Guinea Pigs
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Concept
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Sulfur Radioisotopes
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Concept
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Glucagon
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Concept
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Prospective Studies
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Concept
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Electron Transport
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Concept
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Microbodies
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Concept
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Rats
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Concept
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Chelating Agents
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Concept
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Vitreous Body
|
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Concept
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Sequence Homology, Nucleic Acid
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Concept
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Metals
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Concept
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Axonal Transport
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Concept
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Models, Chemical
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Concept
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Protein Sorting Signals
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Concept
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Enzyme Inhibitors
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Concept
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Receptor, trkA
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Concept
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Rats, Wistar
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Concept
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Aspartic Acid Endopeptidases
|
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Concept
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Breast Neoplasms
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Concept
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Point Mutation
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Concept
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Mice, Neurologic Mutants
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Concept
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Rats, Sprague-Dawley
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Concept
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Receptors, Notch
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Concept
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Polymerase Chain Reaction
|
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Concept
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Presenilin-1
|
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Concept
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Swine
|
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Concept
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Hippocampus
|
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Concept
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Models, Neurological
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Concept
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Chromaffin Granules
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Concept
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Parkinson Disease
|
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Concept
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Cholecalciferol
|
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Concept
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Hypercholesterolemia
|
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Concept
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Cholesterol
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Concept
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MicroRNAs
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Concept
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Risk Factors
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Concept
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alpha-Synuclein
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Concept
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Promoter Regions, Genetic
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Concept
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Environment
|
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Concept
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Phosphatidylinositol 3-Kinases
|
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Concept
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Vitamins
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Concept
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DNA, Z-Form
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Concept
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Base Sequence
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Concept
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Follow-Up Studies
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Concept
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Glucagon-Like Peptide 1
|
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Concept
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Amyloid beta-Peptides
|
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Concept
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Immunohistochemistry
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Concept
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RNA, Antisense
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Concept
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DNA, Single-Stranded
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Concept
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Cold Temperature
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Concept
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Mice, Mutant Strains
|
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Concept
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Immunoblotting
|
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Concept
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Cell Count
|
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Concept
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Deafness
|
|
Academic Article
|
Resolution of inflammation is altered in Alzheimer's disease.
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Academic Article
|
Beta-Amyloid Precursor Protein (?APP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD).
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Concept
|
S100 Calcium Binding Protein G
|
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Concept
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Neuroprotection
|
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Concept
|
Glucagon-Like Peptide-1 Receptor
|
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Concept
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Rivastigmine
|
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Concept
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Gastrointestinal Microbiome
|
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Concept
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Liver X Receptors
|
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Concept
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ADAM17 Protein
|
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Concept
|
Endothelin-Converting Enzymes
|
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Concept
|
Cholesterol 24-Hydroxylase
|
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Academic Article
|
Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss.
|