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Sambamurti, Kumar
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Academic Article Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.
Academic Article A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor.
Academic Article The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells.
Academic Article The role of the carboxyl-terminal fragments of amyloid precursor protein in Alzheimer's disease.
Academic Article 17beta-estradiol reduces plasma Abeta40 for HRT-na?ve postmenopausal women with Alzheimer disease: a preliminary study.
Academic Article Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.
Academic Article Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.
Academic Article High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
Academic Article Value in development of a TAPIR-like mouse monoclonal antibody to Abeta.
Academic Article Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.
Academic Article APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity.
Academic Article Major carboxyl terminal fragments generated by ?-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long.
Academic Article Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Academic Article Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors.
Academic Article An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice.
Concept Peptide Fragments
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  • Peptide Fragments