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Shapiro, Steven
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Item TypeName
Academic Article Regulation of lutropin circulatory half-life by the mannose/N-acetylgalactosamine-4-SO4 receptor is critical for implantation in vivo.
Academic Article Lysyl oxidase is required for vascular and diaphragmatic development in mice.
Academic Article Corneal neovascularization after excimer keratectomy wounds in matrilysin-deficient mice.
Academic Article Inducible expression of tissue inhibitor of metalloproteinases-resistant matrix metalloproteinase-9 on the cell surface of neutrophils.
Academic Article Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.
Academic Article Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice.
Academic Article Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption.
Academic Article Influenza and asthma: adding to the respiratory burden.
Academic Article Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo.
Academic Article Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase.
Academic Article Accelerated enlargement of experimental abdominal aortic aneurysms in a mouse model of chronic cigarette smoke exposure.
Academic Article Induction of macrophage elastase (MMP-12) gene expression by statins.
Academic Article Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways.
Academic Article Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia.
Academic Article Surfactant protein-D regulates soluble CD14 through matrix metalloproteinase-12.
Academic Article NADPH oxidase restrains the matrix metalloproteinase activity of macrophages.
Academic Article Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
Academic Article Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.
Academic Article Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis.
Academic Article Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases.
Academic Article Epithelial cell PPARgamma is an endogenous regulator of normal lung maturation and maintenance.
Academic Article Stage-specific effects of cAMP signaling during distal lung epithelial development.
Academic Article Animal models of asthma: Pro: Allergic avoidance of animal (model[s]) is not an option.
Academic Article An inhaled matrix metalloprotease inhibitor prevents cigarette smoke-induced emphysema in the mouse.
Academic Article Inhaled recombinant alpha 1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.
Academic Article Animal models of pulmonary emphysema.
Academic Article Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Academic Article Lung turns to AA (adenosine analogues) to dry out.
Academic Article Essential role of MMP-12 in Fas-induced lung fibrosis.
Academic Article Genomics and proteomics of lung disease: conference summary.
Academic Article Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury.
Academic Article Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury.
Academic Article The use of transgenic mice for modeling airways disease.
Academic Article Clarithromycin prevents smoke-induced emphysema in mice.
Academic Article Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway.
Academic Article Epithelial cell apoptosis causes acute lung injury masquerading as emphysema.
Academic Article Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth.
Academic Article A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci.
Academic Article Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema.
Academic Article Cigarette smoke inhibits engulfment of apoptotic cells by macrophages through inhibition of actin rearrangement.
Academic Article Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice.
Academic Article Thomas A. Neff lecture. Application of expression profiling to the developing lung: identification of putative regulatory networks controlling matrix production.
Academic Article Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro.
Academic Article Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid.
Academic Article Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release.
Academic Article Immunology: Mobilizing the army.
Academic Article Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.
Academic Article Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice.
Academic Article Smoke and mirrors: Mouse models as a reflection of human chronic obstructive pulmonary disease.
Academic Article Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP.
Academic Article Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen.
Academic Article Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression.
Academic Article Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo.
Academic Article MMP-12 has a role in abdominal aortic aneurysms in mice.
Academic Article Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering.
Academic Article An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization.
Academic Article The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
Academic Article Elastin fragments drive disease progression in a murine model of emphysema.
Academic Article Epithelial cell PPAR[gamma] contributes to normal lung maturation.
Academic Article Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy.
Academic Article Role of FcRs in animal model of autoimmune bullous pemphigoid.
Academic Article The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
Academic Article Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis.
Academic Article Scavenger Receptors SR-AI/II and MARCO limit pulmonary dendritic cell migration and allergic airway inflammation.
Academic Article CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.
Academic Article Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice.
Academic Article Macrophage elastase kills bacteria within murine macrophages.
Academic Article MMP-8 promotes polymorphonuclear cell migration through collagen barriers in obliterative bronchiolitis.
Academic Article Osteoclasts are important for bone angiogenesis.
Academic Article The role of the receptor for advanced glycation end-products in a murine model of silicosis.
Academic Article NET loss of air in cystic fibrosis.
Academic Article IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke.
Academic Article Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.
Academic Article Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase.
Academic Article Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.
Academic Article Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Concept Mice, Inbred BALB C
Concept Mice, Knockout
Concept Mice, Inbred C3H
Concept Mice
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mice, Inbred A
Concept Mice, Inbred AKR
Concept Mice, Inbred Strains
Concept Mice, Mutant Strains
Academic Article Investigating the role of DNA damage in tobacco smoking-induced spine degeneration.
Academic Article Effects of intra-abdominal sepsis on atherosclerosis in mice.
Academic Article Macrophage elastase suppresses white adipose tissue expansion with cigarette smoking.
Academic Article The receptor for advanced glycation end products (RAGE) contributes to the progression of emphysema in mice.
Academic Article Airway epithelial cell PPAR? modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice.
Academic Article Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer.
Academic Article Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.
Academic Article Automated Measurement of Blood Vessels in Tissues from Microscopy Images.
Academic Article Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor.
Academic Article Development of a Mouse Model of Metabolic Syndrome, Pulmonary Hypertension, and Heart Failure with Preserved Ejection Fraction.
Academic Article Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility.
Academic Article Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages.
Academic Article Reply to: Quantitative Histology Seriously Flawed by Lack of Lung Volume Measurement.
Academic Article Differential roles of STAT3 in the initiation and growth of lung cancer.
Academic Article Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Academic Article Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia.
Academic Article Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.
Academic Article FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema.
Academic Article PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis.
Academic Article Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis.
Concept Mice, 129 Strain
Academic Article Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer.
Academic Article Alveolar Macrophages Inherently Express Programmed Death-1 Ligand 1 for Optimal Protective Immunity and Tolerance.
Academic Article RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease.
Academic Article Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD.
Academic Article Cigarette smoking is a secondary cause of folliculin loss.
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