| Item Type | Name |
|
Academic Article
|
Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy.
|
|
Academic Article
|
Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha.
|
|
Academic Article
|
Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
|
|
Academic Article
|
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
|
|
Academic Article
|
Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin.
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|
Academic Article
|
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
|
|
Academic Article
|
Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.
|
|
Academic Article
|
N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
|
|
Academic Article
|
Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability.
|
|
Academic Article
|
Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.
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|
Academic Article
|
A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma.
|
|
Academic Article
|
Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease.
|
|
Academic Article
|
5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.
|
|
Academic Article
|
HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
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|
Academic Article
|
The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats.
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|
Academic Article
|
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
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|
Academic Article
|
Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke.
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|
Academic Article
|
Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease.
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|
Academic Article
|
Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats.
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|
Academic Article
|
T-bet is essential for the progression of experimental autoimmune encephalomyelitis.
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|
Academic Article
|
AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model.
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Academic Article
|
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
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|
Academic Article
|
Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury.
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|
Academic Article
|
Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
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|
Academic Article
|
Lactosylceramide: a lipid second messenger in neuroinflammatory disease.
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|
Academic Article
|
Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
|
|
Academic Article
|
Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathology.
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|
Academic Article
|
Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.
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|
Academic Article
|
Factors that affect postnatal bone growth retardation in the twitcher murine model of Krabbe disease.
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|
Academic Article
|
Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine.
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|
Academic Article
|
Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion.
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|
Academic Article
|
Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
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|
Academic Article
|
The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
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|
Academic Article
|
Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.
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|
Academic Article
|
N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia.
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|
Academic Article
|
Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-a-dependent mechanism.
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|
Academic Article
|
The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.
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|
Academic Article
|
Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line.
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|
Academic Article
|
Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies.
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|
Academic Article
|
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
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|
Academic Article
|
Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E.
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|
Academic Article
|
Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
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Academic Article
|
The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
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|
Academic Article
|
Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats.
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|
Academic Article
|
S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke.
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|
Academic Article
|
Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
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|
Academic Article
|
IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases.
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|
Academic Article
|
Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia.
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|
Academic Article
|
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction.
|
|
Academic Article
|
GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions.
|
|
Academic Article
|
Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures.
|
|
Academic Article
|
Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
|
|
Academic Article
|
The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease.
|
|
Academic Article
|
Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
|
|
Academic Article
|
Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
|
|
Academic Article
|
Attenuation of lipopolysaccharide-induced inflammatory response and phospholipids metabolism at the feto-maternal interface by N-acetyl cysteine.
|
|
Academic Article
|
Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
|
|
Academic Article
|
Psychosine-induced alterations in peroxisomes of twitcher mouse liver.
|
|
Academic Article
|
15-deoxy-delta12,14-prostaglandin J2 attenuates endothelial-monocyte interaction: implication for inflammatory diseases.
|
|
Academic Article
|
Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
|
|
Academic Article
|
Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact.
|
|
Academic Article
|
Activation of PPAR-? and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
|
|
Academic Article
|
Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis.
|
|
Academic Article
|
Synergistic activity of interleukin-17 and tumor necrosis factor-a enhances oxidative stress-mediated oligodendrocyte apoptosis.
|
|
Academic Article
|
S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats.
|
|
Academic Article
|
Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion.
|
|
Academic Article
|
S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions.
|
|
Academic Article
|
Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease.
|
|
Academic Article
|
AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model.
|
|
Concept
|
NADP
|
|
Concept
|
Phenylethyl Alcohol
|
|
Concept
|
Cytokines
|
|
Concept
|
Tissue Distribution
|
|
Concept
|
Immunologic Factors
|
|
Concept
|
Oligodeoxyribonucleotides, Antisense
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Insulin
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Age Factors
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Fibroblasts
|
|
Concept
|
RNA
|
|
Concept
|
Apoptosis
|
|
Concept
|
I-kappa B Kinase
|
|
Concept
|
Drug Administration Schedule
|
|
Concept
|
Tumor Burden
|
|
Concept
|
Molecular Weight
|
|
Concept
|
Interleukin-10
|
|
Concept
|
Protein Transport
|
|
Concept
|
Necrosis
|
|
Concept
|
Protein Prenylation
|
|
Concept
|
Central Nervous System
|
|
Concept
|
Exercise Therapy
|
|
Concept
|
Protein S
|
|
Concept
|
PPAR alpha
|
|
Concept
|
Phospholipases A2, Secretory
|
|
Concept
|
Terpenes
|
|
Concept
|
Kidney Transplantation
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Methionine
|
|
Concept
|
Amyloid beta-Protein Precursor
|
|
Concept
|
Nucleocytoplasmic Transport Proteins
|
|
Concept
|
Microscopy, Electron
|
|
Concept
|
Blood Urea Nitrogen
|
|
Concept
|
Motor Activity
|
|
Concept
|
Hypoxia-Ischemia, Brain
|
|
Concept
|
Synaptosomes
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Bone Development
|
|
Concept
|
Antigens
|
|
Concept
|
Catalase
|
|
Concept
|
Arachidonic Acid
|
|
Concept
|
Wallerian Degeneration
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Aldehydes
|
|
Concept
|
Blood Pressure
|
|
Concept
|
Myelin Sheath
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Polyradiculopathy
|
|
Concept
|
Prostaglandin D2
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Cyclin-Dependent Kinase 5
|
|
Concept
|
Mitochondria
|
|
Concept
|
Bone Diseases, Developmental
|
|
Concept
|
Brain
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Interphase
|
|
Concept
|
Brain Diseases
|
|
Concept
|
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
|
|
Concept
|
Infant
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
Embryo, Mammalian
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Neurologic Examination
|
|
Concept
|
Hypothermia, Induced
|
|
Concept
|
S Phase
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
Gene Expression
|
|
Concept
|
Genes, MHC Class II
|
|
Concept
|
Drug Therapy, Combination
|
|
Concept
|
Intercellular Adhesion Molecule-1
|
|
Concept
|
Cell Communication
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Receptor, Platelet-Derived Growth Factor alpha
|
|
Concept
|
Paralysis
|
|
Concept
|
RNA Interference
|
|
Concept
|
Hypertension
|
|
Concept
|
PC12 Cells
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Microarray Analysis
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
L-Lactate Dehydrogenase
|
|
Concept
|
Adenosine Kinase
|
|
Concept
|
Capillary Permeability
|
|
Concept
|
Disease Progression
|
|
Concept
|
Lymphocyte Count
|
|
Concept
|
Hypoglycemic Agents
|
|
Concept
|
Kidney Diseases
|
|
Concept
|
Biological Availability
|
|
Concept
|
Polyethylene Glycols
|
|
Concept
|
Ceramides
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Hydroxymethylglutaryl CoA Reductases
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Cell Adhesion Molecules
|
|
Concept
|
Plasmalogens
|
|
Concept
|
Cell Survival
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Sphingomyelin Phosphodiesterase
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
rho GTP-Binding Proteins
|
|
Concept
|
Infectious Disease Transmission, Vertical
|
|
Concept
|
Myelin Proteolipid Protein
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Calcitriol
|
|
Concept
|
DNA Fragmentation
|
|
Concept
|
Macrophages
|
|
Concept
|
Rats, Inbred Lew
|
|
Concept
|
Genomics
|
|
Concept
|
Membrane Potential, Mitochondrial
|
|
Concept
|
Administration, Oral
|
|
Concept
|
Glucosephosphate Dehydrogenase
|
|
Concept
|
Lysosomes
|
|
Concept
|
Arginine
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Combined Modality Therapy
|
|
Concept
|
Dogs
|
|
Concept
|
Mediator Complex
|
|
Concept
|
E1A-Associated p300 Protein
|
|
Concept
|
Chromones
|
|
Concept
|
Ubiquitin
|
|
Concept
|
Animals
|
|
Concept
|
Glial Fibrillary Acidic Protein
|
|
Concept
|
Blotting, Northern
|
|
Concept
|
Mitochondrial Proteins
|
|
Concept
|
Activating Transcription Factor 2
|
|
Concept
|
Regional Blood Flow
|
|
Concept
|
Vitamin E
|
|
Concept
|
Nitrosoguanidines
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Phosphodiesterase Inhibitors
|
|
Concept
|
Contusions
|
|
Concept
|
Encephalomyelitis, Autoimmune, Experimental
|
|
Concept
|
Ciliary Neurotrophic Factor
|
|
Concept
|
Chronic Disease
|
|
Concept
|
Freund's Adjuvant
|
|
Concept
|
Psychosine
|
|
Concept
|
Nephrectomy
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Insulin-Like Growth Factor I
|
|
Concept
|
Drug Delivery Systems
|
|
Concept
|
Raffinose
|
|
Concept
|
Membrane Lipids
|
|
Concept
|
Random Allocation
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Vasodilator Agents
|
|
Concept
|
Ectodysplasins
|
|
Concept
|
Heme Oxygenase-1
|
|
Concept
|
Alcohol Dehydrogenase
|
|
Concept
|
Wound Healing
|
|
Concept
|
Hydroxamic Acids
|
|
Concept
|
Urination Disorders
|
|
Concept
|
Peptide Fragments
|
|
Concept
|
Endothelial Cells
|
|
Concept
|
Cisplatin
|
|
Concept
|
Antineoplastic Agents
|
|
Concept
|
Neoplasms, Experimental
|
|
Concept
|
Stroke
|
|
Concept
|
Lipid Peroxidation
|
|
Concept
|
Glycopeptides
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Phospholipases A
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Urodynamics
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Reperfusion
|
|
Concept
|
Bone Remodeling
|
|
Concept
|
Glutathione
|
|
Concept
|
CHO Cells
|
|
Concept
|
Blotting, Western
|
|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
Synaptophysin
|
|
Concept
|
E-Selectin
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Mental Disorders
|
|
Concept
|
Neuroprotective Agents
|
|
Concept
|
Nerve Regeneration
|
|
Concept
|
Cricetulus
|
|
Concept
|
Drug Interactions
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Acetylcysteine
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Cognition Disorders
|
|
Concept
|
Biomarkers
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
Glioma
|
|
Concept
|
Epitopes, T-Lymphocyte
|
|
Concept
|
Membrane Microdomains
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Sphingosine
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Chemotaxis, Leukocyte
|
|
Concept
|
Leupeptins
|
|
Concept
|
Nervous System Diseases
|
|
Concept
|
Motor Skills
|
|
Concept
|
Leukotriene B4
|
|
Concept
|
Brain Edema
|
|
Concept
|
Growth Inhibitors
|
|
Concept
|
Head and Neck Neoplasms
|
|
Concept
|
Acyl-CoA Oxidase
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Biopsy, Needle
|
|
Concept
|
Caspase 3
|
|
Concept
|
Urinary Bladder
|
|
Concept
|
Monomeric GTP-Binding Proteins
|
|
Concept
|
Enzyme Induction
|
|
Concept
|
Cerebrovascular Disorders
|
|
Concept
|
Child, Preschool
|
|
Concept
|
Mice
|
|
Concept
|
Galactosyltransferases
|
|
Concept
|
Protective Agents
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Inflammation Mediators
|
|
Concept
|
Functional Laterality
|
|
Concept
|
Aging
|
|
Concept
|
Nitroprusside
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
DNA Primers
|
|
Concept
|
Cyclooxygenase 2
|
|
Concept
|
tau Proteins
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Models, Biological
|
|
Concept
|
Statistics, Nonparametric
|
|
Concept
|
rhoA GTP-Binding Protein
|
|
Concept
|
Lipids
|
|
Concept
|
Drug Evaluation, Preclinical
|
|
Concept
|
Maternal-Fetal Exchange
|
|
Concept
|
Isoenzymes
|
|
Concept
|
Immunomodulation
|
|
Concept
|
Encephalitis
|
|
Concept
|
Caffeic Acids
|
|
Concept
|
Edema
|
|
Concept
|
Brain Chemistry
|
|
Concept
|
Pyrroles
|
|
Concept
|
Oligodendroglia
|
|
Concept
|
Lipoxygenase
|
|
Concept
|
CCAAT-Enhancer-Binding Protein-delta
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Middle Cerebral Artery
|
|
Concept
|
Dinoprostone
|
|
Concept
|
Proteoglycans
|
|
Concept
|
Glutathione Peroxidase
|
|
Concept
|
Peroxisomal Disorders
|
|
Concept
|
Immunity, Innate
|
|
Concept
|
Matrix Metalloproteinase 9
|
|
Concept
|
Behavior, Animal
|
|
Concept
|
Cerebral Cortex
|
|
Concept
|
Seizures
|
|
Concept
|
Growth Substances
|
|
Concept
|
T-Box Domain Proteins
|
|
Concept
|
Organ Specificity
|
|
Concept
|
Adult
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Lysine
|
|
Concept
|
Maze Learning
|
|
Concept
|
Anti-Inflammatory Agents
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
Galactosylceramides
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Male
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Gait Disorders, Neurologic
|
|
Concept
|
Lysophosphatidylcholines
|
|
Concept
|
Stem Cells
|
|
Concept
|
Tyrosine
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Recovery of Function
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Nitric Oxide Synthase
|
|
Concept
|
Locomotion
|
|
Concept
|
Nervous System
|
|
Concept
|
Organ Preservation Solutions
|
|
Concept
|
Phosphopyruvate Hydratase
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Injections, Intraperitoneal
|
|
Concept
|
Adenosine
|
|
Concept
|
Drug Synergism
|
|
Concept
|
Adrenoleukodystrophy
|
|
Concept
|
Signal Transduction
|
|
Concept
|
Heart Rate
|
|
Concept
|
Monocytes
|
|
Concept
|
Arachidonate 5-Lipoxygenase
|
|
Concept
|
Proteinuria
|
|
Concept
|
Disease
|
|
Concept
|
Female
|
|
Concept
|
Free Radical Scavengers
|
|
Concept
|
Nitric Oxide Synthase Type III
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Lovastatin
|
|
Concept
|
Lymphoid Tissue
|
|
Concept
|
Glutathione Transferase
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Time Factors
|
|
Concept
|
Multiple Myeloma
|
|
Concept
|
Survival Rate
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Humans
|
|
Concept
|
Nerve Degeneration
|
|
Concept
|
Oxidative Stress
|
|
Concept
|
Benzodioxoles
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Vitamin D
|
|
Concept
|
Brain Ischemia
|
|
Concept
|
Leukomalacia, Periventricular
|
|
Concept
|
Organ Size
|
|
Concept
|
Child
|
|
Concept
|
Cell Movement
|
|
Concept
|
Neurons
|
|
Concept
|
Antigen Presentation
|
|
Concept
|
Urinary Bladder Diseases
|
|
Concept
|
Spinal Cord
|
|
Concept
|
S-Nitrosoglutathione
|
|
Concept
|
Nerve Fibers, Myelinated
|
|
Concept
|
Superoxide Dismutase
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Astrocytes
|
|
Concept
|
Sepsis
|
|
Concept
|
Liver
|
|
Concept
|
Nitro Compounds
|
|
Concept
|
Interleukin-1
|
|
Concept
|
Cell Death
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Phospholipids
|
|
Concept
|
Prenatal Exposure Delayed Effects
|
|
Concept
|
Colforsin
|
|
Concept
|
Adoptive Transfer
|
|
Concept
|
Ischemia
|
|
Concept
|
Calpain
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Allopurinol
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Tetrazolium Salts
|
|
Concept
|
Oncogene Protein v-akt
|
|
Concept
|
Macrophages, Peritoneal
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Caspases
|
|
Concept
|
Inflammation
|
|
Concept
|
CD11b Antigen
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Permeability
|
|
Concept
|
Brain Injuries
|
|
Concept
|
Galactosides
|
|
Concept
|
Fatty Acids, Unsaturated
|
|
Concept
|
Neuroglia
|
|
Concept
|
Transcription Factor AP-1
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Interleukin-17
|
|
Concept
|
Ribonucleotides
|
|
Concept
|
Malondialdehyde
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Coculture Techniques
|
|
Concept
|
Demyelinating Diseases
|
|
Concept
|
Multienzyme Complexes
|
|
Concept
|
Kainic Acid
|
|
Concept
|
ATP-Binding Cassette Transporters
|
|
Concept
|
Hyperalgesia
|
|
Concept
|
ras Proteins
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Rolipram
|
|
Concept
|
Microglia
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Nerve Growth Factors
|
|
Concept
|
Cerebrovascular Circulation
|
|
Concept
|
Polyisoprenyl Phosphates
|
|
Concept
|
Response Elements
|
|
Concept
|
Antioxidants
|
|
Concept
|
Peroxynitrous Acid
|
|
Concept
|
Molsidomine
|
|
Concept
|
Fatty Acids
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Group II Phospholipases A2
|
|
Concept
|
Protein Stability
|
|
Concept
|
Second Messenger Systems
|
|
Concept
|
O Antigens
|
|
Concept
|
Pregnancy
|
|
Concept
|
Placenta
|
|
Concept
|
Alzheimer Disease
|
|
Concept
|
Oligonucleotides, Antisense
|
|
Concept
|
Cell Migration Inhibition
|
|
Concept
|
Myelin Basic Protein
|
|
Concept
|
Kidney
|
|
Concept
|
Electrophoretic Mobility Shift Assay
|
|
Concept
|
Acetylation
|
|
Concept
|
Th1 Cells
|
|
Concept
|
Amino Acid Oxidoreductases
|
|
Concept
|
Gliosis
|
|
Concept
|
Receptors, Lysosphingolipid
|
|
Concept
|
Interleukin-4
|
|
Concept
|
Carcinoma, Squamous Cell
|
|
Concept
|
GATA3 Transcription Factor
|
|
Concept
|
Transcription Factors
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Aminoimidazole Carboxamide
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
rho-Associated Kinases
|
|
Concept
|
Ischemic Preconditioning
|
|
Concept
|
Neoplasm Proteins
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Induced Pluripotent Stem Cells
|
|
Concept
|
CCAAT-Enhancer-Binding Proteins
|
|
Concept
|
Sphingomyelins
|
|
Concept
|
Nitrites
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
Gamma Rays
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
Cystitis
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
|
Concept
|
Nitric Oxide Synthase Type I
|
|
Concept
|
Organ Preservation
|
|
Concept
|
Galactosylceramidase
|
|
Concept
|
Rats
|
|
Concept
|
Lactosylceramides
|
|
Concept
|
PPAR gamma
|
|
Concept
|
Reperfusion Injury
|
|
Concept
|
I-kappa B Proteins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Leukodystrophy, Globoid Cell
|
|
Concept
|
Receptor, trkB
|
|
Concept
|
Drug Resistance, Neoplasm
|
|
Concept
|
Spleen
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Thiobarbituric Acid Reactive Substances
|
|
Concept
|
Free Radicals
|
|
Concept
|
Proline
|
|
Concept
|
Spinal Cord Injuries
|
|
Concept
|
Fetus
|
|
Concept
|
Glutathione Disulfide
|
|
Concept
|
Evans Blue
|
|
Concept
|
Lipid Metabolism
|
|
Concept
|
Benzamides
|
|
Concept
|
Multiple Sclerosis
|
|
Concept
|
Creatinine
|
|
Concept
|
Th2 Cells
|
|
Concept
|
2',3'-Cyclic-Nucleotide Phosphodiesterases
|
|
Concept
|
Alkyl and Aryl Transferases
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Anticholesteremic Agents
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Cell Line
|
|
Concept
|
Nitric Oxide Synthase Type II
|
|
Concept
|
Heptanoic Acids
|
|
Concept
|
Graft Survival
|
|
Concept
|
Adenosine Triphosphatases
|
|
Concept
|
Models, Theoretical
|
|
Concept
|
Dynamins
|
|
Concept
|
Pre-Eclampsia
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
B-Lymphocytes
|
|
Concept
|
Metformin
|
|
Concept
|
Transfection
|
|
Concept
|
Mice, Neurologic Mutants
|
|
Concept
|
Phospholipases A2
|
|
Concept
|
Transplantation, Autologous
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Glycoproteins
|
|
Concept
|
Hippocampus
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
Nitric Oxide Donors
|
|
Concept
|
Central Nervous System Agents
|
|
Concept
|
Morpholines
|
|
Concept
|
Probability
|
|
Concept
|
Neuropsychological Tests
|
|
Concept
|
Apoptosis Regulatory Proteins
|
|
Concept
|
Steroid Hydroxylases
|
|
Concept
|
Neural Pathways
|
|
Concept
|
Cholecalciferol
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Propidium
|
|
Concept
|
Ischemic Attack, Transient
|
|
Concept
|
Cholesterol
|
|
Concept
|
Neoplasms
|
|
Concept
|
Annexin A5
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Mevalonic Acid
|
|
Concept
|
Superoxides
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Uterus
|
|
Concept
|
Janus Kinase 2
|
|
Concept
|
Adenylate Kinase
|
|
Concept
|
Arachidonic Acids
|
|
Concept
|
Risk Factors
|
|
Concept
|
Chemokines
|
|
Concept
|
Glutathione S-Transferase pi
|
|
Concept
|
Brain Infarction
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Dehydroepiandrosterone
|
|
Concept
|
Infarction, Middle Cerebral Artery
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Gene Knockout Techniques
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Base Sequence
|
|
Concept
|
Amyloid beta-Peptides
|
|
Concept
|
Transcriptional Activation
|
|
Concept
|
Biosynthetic Pathways
|
|
Concept
|
In Situ Nick-End Labeling
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Acyltransferases
|
|
Concept
|
Immune Tolerance
|
|
Concept
|
Transcription Factor RelA
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Fetal Weight
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Brain-Derived Neurotrophic Factor
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Thiocarbamates
|
|
Concept
|
Pertussis Toxin
|
|
Concept
|
Receptors, Cytoplasmic and Nuclear
|
|
Concept
|
Peroxisomes
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Immunologic Memory
|
|
Concept
|
Myelitis
|
|
Concept
|
Cell Count
|
|
Concept
|
Phosphorylation
|
|
Concept
|
Glucose
|
|
Academic Article
|
PPARa activation induces N(e)-Lys-acetylation of rat liver peroxisomal multifunctional enzyme type 1.
|
|
Academic Article
|
STAT3 regulation by S-nitrosylation: implication for inflammatory disease.
|
|
Academic Article
|
Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease.
|
|
Academic Article
|
S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling.
|
|
Academic Article
|
ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy.
|
|
Academic Article
|
Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation.
|
|
Academic Article
|
Promoting endothelial function by S-nitrosoglutathione through the HIF-1a/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats.
|
|
Academic Article
|
Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats.
|
|
Academic Article
|
Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy.
|
|
Academic Article
|
S-Nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma.
|
|
Academic Article
|
S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion.
|
|
Academic Article
|
AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis.
|
|
Academic Article
|
Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy.
|
|
Academic Article
|
Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI.
|
|
Academic Article
|
S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis.
|
|
Academic Article
|
N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats.
|
|
Academic Article
|
Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease.
|
|
Academic Article
|
GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1a.
|
|
Academic Article
|
Regulation of STAT3 and NF-?B activations by S-nitrosylation in multiple myeloma.
|
|
Academic Article
|
Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model.
|
|
Academic Article
|
S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis.
|
|
Academic Article
|
Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.
|
|
Academic Article
|
Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione.
|
|
Academic Article
|
Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI.
|
|
Academic Article
|
Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity.
|
|
Academic Article
|
Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries.
|
|
Academic Article
|
S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke.
|
|
Academic Article
|
Detoxification of Reactive Aldehydes by Alda-1 Treatment Ameliorates Experimental Autoimmune Encephalomyelitis in Mice.
|
|
Academic Article
|
GSNOR and ALDH2 alleviate traumatic spinal cord injury.
|
|
Academic Article
|
Asymmetric dimethylarginine exacerbates cognitive dysfunction associated with cerebrovascular pathology.
|
|
Academic Article
|
Optical Pooled Screens in Human Cells.
|
|
Academic Article
|
Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke.
|
|
Concept
|
Neural Stem Cells
|
|
Concept
|
Nociception
|
|
Concept
|
GABAergic Neurons
|
|
Concept
|
Proteolysis
|
|
Concept
|
Endoplasmic Reticulum Stress
|
|
Concept
|
Acute Kidney Injury
|
|
Concept
|
Th17 Cells
|
|
Concept
|
Cognitive Dysfunction
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
Brain Injuries, Traumatic
|
|
Concept
|
Matrix Metalloproteinase Inhibitors
|
|
Concept
|
Proteasome Inhibitors
|
|
Concept
|
Zonula Occludens-1 Protein
|
|
Concept
|
Myelin-Oligodendrocyte Glycoprotein
|
|
Concept
|
CRISPR-Cas Systems
|
|
Concept
|
Vitamin D3 24-Hydroxylase
|
|
Concept
|
In Vitro Techniques
|
|
Concept
|
Behavior Rating Scale
|
|
Concept
|
Fingolimod Hydrochloride
|
|
Concept
|
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
|
|
Concept
|
Aldehyde Dehydrogenase, Mitochondrial
|
|
Concept
|
ATPases Associated with Diverse Cellular Activities
|
|
Concept
|
Glycogen Synthase Kinase 3 beta
|
|
Concept
|
Superoxide Dismutase-1
|
|
Academic Article
|
Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms.
|
|
Academic Article
|
Regulation of B cell functions by S-nitrosoglutathione in the EAE model.
|
|
Academic Article
|
Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis.
|
|
Academic Article
|
Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation.
|