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Smith, Charles
One or more keywords matched the following items that are connected to Smith, Charles
Item TypeName
Academic Article Discovery and evaluation of inhibitors of human sphingosine kinase.
Academic Article Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein.
Academic Article Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article Combined anticancer effects of sphingosine kinase inhibitors and sorafenib.
Academic Article The Pim protein kinases regulate energy metabolism and cell growth.
Academic Article 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance.
Academic Article Quinacrine synergizes with 5-fluorouracil and other therapies in colorectal cancer.
Academic Article Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration.
Academic Article Discovery and characterization of inhibitors of human palmitoyl acyltransferases.
Academic Article A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Academic Article Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2.
Academic Article DHHC20: a human palmitoyl acyltransferase that causes cellular transformation.
Academic Article Discovery and evaluation of inhibitors of human ceramidase.
Academic Article Characterization of isoenzyme-selective inhibitors of human sphingosine kinases.
Concept Cell Line, Tumor
Academic Article Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.
Academic Article Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.
Academic Article Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors.
Academic Article Discovery of novel antitumor antimitotic agents that also reverse tumor resistance.
Academic Article Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.
Academic Article Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development.
Academic Article Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.
Academic Article Targeting NF?B mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2.
Academic Article Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640.
Academic Article Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.
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  • Cell Line Tumor