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One or more keywords matched the following properties of Smolka, Adam
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keywords Pathophysiology of Helicobacter pylori
overview Dr. Smolka is Professor of Medicine in the Division of Gastroenterology and Hepatology at the Medical University of South Carolina. He earned his PhD in Physiology and Biophysics in 1982 at the University of Alabama, Birmingham. Following postdoctoral studies at the University of California, Los Angeles, he was appointed Assistant Professor in the Department of Medicine at UCLA in 1984. Dr. Smolka was appointed Associate Professor in the Department of Anatomy and Cell Biology at MUSC in 1992, and tenured full Professor in the Department of Medicine at MUSC in 1998. Dr. Smolka is Course Director of the First Year Curriculum in the MUSC College of Graduate Studies and chair of the College Curriculum Committee. He is a member and fellow of the American Gastroenterological Association, American Physiological Association, American Association for the Advancement of Science, American Society for Cell Biology, and the Parietal Cell Club. Additionally, he is a member of Hollings Cancer Center at MUSC, and a past Universities Space Research Association Scholar and member of the NASA Biotechnology Fundamentals Study Section. Dr. Smolka’s current research interests include pathophysiology of Helicobacter pylori infection of the gastric mucosa, molecular structure-function relationships in the gastric proton pump, and proteomic analysis of esophageal cancers. Previous research at NASA Marshall Space Flight Center, Huntsville, Alabama, focused on bioseparations technology, including microgravity cell electrophoresis (a sample of his blood was processed in earth orbit on Skylab II), and modification of cell electrophoretic mobility using synthetic polymeric microspheres. Dr. Smolka has published extensively (60 papers, 15 book chapters, and 70 abstracts), and since 1984 has been Principal Investigator on five major National Institutes of Health grant awards, and one NASA award.
One or more keywords matched the following items that are connected to Smolka, Adam
Item TypeName
Academic Article Inhibition of human gastric H(+)-K(+)-ATPase alpha-subunit gene expression by Helicobacter pylori.
Academic Article IL-1beta modulation of H,K-ATPase alpha-subunit gene transcription in Helicobacter pylori infection.
Academic Article The role of Sp1 in IL-1beta and H. pylori-mediated regulation of H,K-ATPase gene transcription.
Academic Article A small fibronectin-mimicking protein from bacteria induces cell spreading and focal adhesion formation.
Academic Article c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains.
Academic Article Interleukin 1beta induces gastric epithelial cell matrix metalloproteinase secretion and activation during Helicobacter pylori infection.
Academic Article Helicobacter pylori-induced H,K-ATPase alpha-subunit gene repression is mediated by NF-kappaB p50 homodimer promoter binding.
Academic Article Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit.
Academic Article Helicobacter pylori represses proton pump expression and inhibits acid secretion in human gastric mucosa.
Academic Article How Helicobacter pylori infection controls gastric acid secretion.
Academic Article Parietal cells in the duodenal bulb and their relation to Helicobacter pylori infection.
Concept Helicobacter pylori
Concept Helicobacter Infections
Academic Article Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase a-subunit gene expression by miRNA.
Academic Article Helicobacter pylori virulence factors affecting gastric proton pump expression and acid secretion.
Academic Article Helicobacter pylori-Induced Changes in Gastric Acid Secretion and Upper Gastrointestinal Disease.
Academic Article Gastric Parietal Cell Physiology and Helicobacter pylori-Induced Disease.
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  • Helicobacter