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Academic Article
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Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation.
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Academic Article
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Mouse complement receptor-related gene y/p65-neutralized tumor vaccine induces antitumor activity in vivo.
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Academic Article
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A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.
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Academic Article
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App1: an antiphagocytic protein that binds to complement receptors 3 and 2.
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Academic Article
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A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
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Academic Article
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Complement-dependent inflammation and injury in a murine model of brain dead donor hearts.
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Academic Article
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Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
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Academic Article
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Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion.
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Academic Article
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The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury.
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Academic Article
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Complement inhibition alleviates paraquat-induced acute lung injury.
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Academic Article
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CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants.
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Academic Article
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The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.
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Academic Article
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A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer.
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Academic Article
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The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.
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Academic Article
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The alternative complement pathway propagates inflammation and injury in murine ischemic stroke.
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Academic Article
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Targeting complement component 5a promotes vascular integrity and limits airway remodeling.
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Academic Article
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The effect of dexamethasone on human mucin 1 expression and antibody-dependent complement sensitivity in a prostate cancer cell line in vitro and in vivo.
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Academic Article
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A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans.
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Academic Article
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Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.
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Academic Article
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Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer.
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Academic Article
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Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.
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Academic Article
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Complement-dependent P-selectin expression and injury following ischemic stroke.
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Academic Article
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Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement.
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Academic Article
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A complement C3 inhibitor specifically targeted to sites of complement activation effectively ameliorates collagen-induced arthritis in DBA/1J mice.
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Academic Article
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Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
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Academic Article
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Modulation of protective T cell immunity by complement inhibitor expression on tumor cells.
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Academic Article
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A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury.
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Academic Article
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Ketamine-xylazine-acepromazine compared with isoflurane for anesthesia during liver transplantation in rodents.
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Academic Article
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A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitor.
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Academic Article
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Targeted inhibition of complement activation prevents features of preeclampsia in mice.
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Academic Article
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Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.
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Academic Article
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The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
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Academic Article
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Complement and the alternative pathway play an important role in LPS/D-GalN-induced fulminant hepatic failure.
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Academic Article
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The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation.
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Academic Article
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Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis.
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Academic Article
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A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor.
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Academic Article
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Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts.
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Concept
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Mice, Inbred CBA
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Inbred MRL lpr
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Concept
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Mice, Inbred C3H
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Concept
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Mice, Inbred ICR
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Inbred NOD
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Concept
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Mice, Inbred NZB
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Concept
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Mice, Inbred DBA
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Academic Article
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Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE.
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Academic Article
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Complement-dependent modulation of antitumor immunity following radiation therapy.
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Academic Article
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Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy.
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Academic Article
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Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid.
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Academic Article
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A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury.
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Academic Article
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Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement.
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Academic Article
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IL-1a and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells.
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Academic Article
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Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis.
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Academic Article
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A new mouse anti-mouse complement receptor type 2 and 1 (CR2/CR1) monoclonal antibody as a tool to study receptor involvement in chronic models of immune responses and disease.
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Academic Article
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Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury.
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Academic Article
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Early Application of Auxiliary Partial Orthotopic Liver Transplantation in Murine Model of Wilson Disease.
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Academic Article
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Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency.
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Academic Article
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Surface Expression of TGF? Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer.
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Academic Article
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Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice.
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Academic Article
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Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement.
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Academic Article
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Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy.
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Academic Article
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New Insights on Complement Inhibitor CD59 in Mouse Laser-Induced Choroidal Neovascularization: Mislocalization After Injury and Targeted Delivery for Protein Replacement.
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Academic Article
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Identifying the Role of Complement in Triggering Neuroinflammation after Traumatic Brain Injury.
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Academic Article
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C3a receptor antagonism as a novel therapeutic target for chronic rhinosinusitis.
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Academic Article
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Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice.
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Academic Article
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Acute Complement Inhibition Potentiates Neurorehabilitation and Enhances tPA-Mediated Neuroprotection.
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Academic Article
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Pharmacological Stimulation of Mitochondrial Biogenesis Using the Food and Drug Administration-Approved ?2-Adrenoreceptor Agonist Formoterol for the Treatment of Spinal Cord Injury.
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Academic Article
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Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.
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Academic Article
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Acid sphingomyelinase deficiency protects mitochondria and improves function recovery after brain injury.
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Academic Article
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CBX8 exhibits oncogenic properties and serves as a prognostic factor in hepatocellular carcinoma.
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Academic Article
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Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
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Academic Article
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C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.
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Academic Article
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Complement Drives Synaptic Degeneration and Progressive Cognitive Decline in the Chronic Phase after Traumatic Brain Injury.
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Academic Article
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Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration.
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Academic Article
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Complement mediates neuroinflammation and cognitive decline at extended chronic time points after traumatic brain injury.
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Academic Article
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Complement-Dependent Synaptic Uptake and Cognitive Decline after Stroke and Reperfusion Therapy.
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Academic Article
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In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries.
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Academic Article
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Increasing the efficacy and safety of a human complement inhibitor for treating post-transplant cardiac ischemia reperfusion injury by targeting to a graft-specific neoepitope.
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Academic Article
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Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation.
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