Item Type | Name |
Academic Article
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EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes.
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Academic Article
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Defects of DNA mismatch repair in human prostate cancer.
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Academic Article
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D-elg, a member of the Drosophila ets gene family: sequence, expression and evolutionary comparison.
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Academic Article
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The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformation.
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Academic Article
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Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta.
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Academic Article
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ETS2 function is required to maintain the transformed state of human prostate cancer cells.
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Academic Article
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EAPII interacts with ETS1 and modulates its transcriptional function.
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Academic Article
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Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin.
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Academic Article
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CaSm antisense gene therapy: a novel approach for the treatment of pancreatic cancer.
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Academic Article
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The epithelial-specific Ets factors occupy a unique position in defining epithelial proliferation, differentiation and carcinogenesis.
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Academic Article
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Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression.
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Academic Article
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Ets-dependent regulation of target gene expression during megakaryopoiesis.
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Academic Article
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Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells.
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Academic Article
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Developmental expression pattern of D-ets4, the Drosophila homologue of human Pdef.
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Academic Article
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SP100 inhibits ETS1 activity in primary endothelial cells.
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Academic Article
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Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor.
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Academic Article
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The FLI-1 transcription factor is a short-lived phosphoprotein in T cells.
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Academic Article
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ETS transcription factors and their emerging roles in human cancer.
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Academic Article
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The human ETS1 gene: genomic structure, promoter characterization and alternative splicing.
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Academic Article
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Transcription factor Ets-1 regulates fibroblast growth factor-1-mediated angiogenesis in vivo: role of Ets-1 in the regulation of the PI3K/AKT/MMP-1 pathway.
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Academic Article
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Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins.
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Academic Article
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Oncogene
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Academic Article
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Regulation of Ets function by protein - protein interactions.
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Academic Article
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ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer.
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Academic Article
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CaSm (LSm-1) overexpression in lung cancer and mesothelioma is required for transformed phenotypes.
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Academic Article
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The ETS family of genes: structural analysis, gene products, and involvement in neoplasia and other pathologies.
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Academic Article
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The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice.
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Academic Article
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MicroRNA-mediated inhibition of prostate-derived Ets factor messenger RNA translation affects prostate-derived Ets factor regulatory networks in human breast cancer.
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Academic Article
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Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy.
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Academic Article
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Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.
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Academic Article
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Molecular and functional characterization of the promoter of ETS2, the human c-ets-2 gene.
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Academic Article
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Transcriptional regulation of p21/CIP1 cell cycle inhibitor by PDEF controls cell proliferation and mammary tumor progression.
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Academic Article
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Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy.
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Academic Article
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Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice.
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Academic Article
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Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.
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Academic Article
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Expression of human and viral ets genes in E. coli production of human ets-2-specific monoclonal antibodies.
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Academic Article
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Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
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Academic Article
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Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer.
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Academic Article
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Understanding the role of ETS-mediated gene regulation in complex biological processes.
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Academic Article
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The Drosophila ets-2 gene: molecular structure, chromosomal localization, and developmental expression.
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Academic Article
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A unique amino-terminal sequence predicted for the chicken proto-ets protein.
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Academic Article
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Oncogenes: molecular probes for clinical application in malignant diseases.
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Academic Article
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Transactivation of GATA-1 promoter with ETS1, ETS2 and ERGB/Hu-FLI-1 proteins: stabilization of the ETS1 protein binding on GATA-1 promoter sequences by monoclonal antibody.
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Academic Article
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Interaction of ETS-1 and ERGB/FLI-1 proteins with DNA is modulated by spacing between multiple binding sites as well as phosphorylation.
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Academic Article
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The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors.
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Academic Article
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Generation and characterization of monoclonal antibodies against the ERGB/FLI-1 transcription factor.
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Academic Article
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Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype.
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Academic Article
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FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements.
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Academic Article
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Ets proteins in biological control and cancer.
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Academic Article
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Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells.
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Academic Article
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Dysregulation of granulocyte, erythrocyte, and NK cell lineages in Fli-1 gene-targeted mice.
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Academic Article
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Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
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Academic Article
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Molecular analysis of the ets genes and their products.
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Academic Article
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Establishing a murine pancreatic cancer CaSm model: up-regulation of CaSm is required for the transformed phenotype of murine pancreatic adenocarcinoma.
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Academic Article
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CaSm-mediated cellular transformation is associated with altered gene expression and messenger RNA stability.
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Academic Article
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Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis.
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Academic Article
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Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer.
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Academic Article
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Prostate-derived ETS factor is a mediator of metastatic potential through the inhibition of migration and invasion in breast cancer.
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Academic Article
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ETS family of genes in leukemia and Down syndrome.
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Academic Article
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Thymomegaly, microsplenia, and defective homeostatic proliferation of peripheral lymphocytes in p51-Ets1 isoform-specific null mice.
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Academic Article
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Defining ETS transcription regulatory networks and their contribution to breast cancer progression.
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Academic Article
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Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression.
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Academic Article
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Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin.
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Academic Article
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PDEF is a negative regulator of colon cancer cell growth and migration.
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Academic Article
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Mechanisms and functional consequences of PDEF protein expression loss during prostate cancer progression.
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Academic Article
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Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia.
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Academic Article
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The transcription factor Fli-1 regulates monocyte, macrophage and dendritic cell development in mice.
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Academic Article
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c-ets-2 protooncogene has mitogenic and oncogenic activity.
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Academic Article
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Mammalian ets-1 and ets-2 genes encode highly conserved proteins.
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Academic Article
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Viral myc genes and their cellular homologs.
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Academic Article
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Molecular organization of the chicken ets locus.
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Academic Article
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Molecular evolution of ets genes from avians to mammals and their cytogenetic localization to regions involved in leukemia.
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Academic Article
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The EndoA enhancer contains multiple ETS binding site repeats and is regulated by ETS proteins.
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Academic Article
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Genomic dispersal of the ets gene family during metazoan evolution.
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Academic Article
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Multiple regulatory regions control the expression of Ets-1 in the developing mouse: vascular expression conferred by intron I.
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Academic Article
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Functional relationships among ETS gene family members.
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Concept
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Proto-Oncogene Protein c-ets-1
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Concept
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Proto-Oncogene Protein c-fli-1
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Concept
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Proto-Oncogenes
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Concept
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Proto-Oncogene Protein c-ets-2
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Concept
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Proto-Oncogene Proteins c-myb
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Proto-Oncogene Proteins c-raf
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Proto-Oncogene Proteins
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Concept
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Proto-Oncogene Proteins c-ets
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Academic Article
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Fli1 acts downstream of Etv2 to govern cell survival and vascular homeostasis via positive autoregulation.
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Academic Article
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Fli-1 controls transcription from the MCP-1 gene promoter, which may provide a novel mechanism for chemokine and cytokine activation.
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Academic Article
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FLI1 expression is correlated with breast cancer cellular growth, migration, and invasion and altered gene expression.
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