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One or more keywords matched the following items that are connected to Lilly, Michael
Item TypeName
Academic Article Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
Academic Article Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation.
Academic Article The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Academic Article The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Academic Article Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Academic Article Synergistic antileukemic effects between ABT-869 and chemotherapy involve downregulation of cell cycle-regulated genes and c-Mos-mediated MAPK pathway.
Academic Article The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.
Academic Article PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.
Academic Article Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Academic Article Varied differentiation responses of human leukemias to bryostatin 1.
Academic Article Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.
Academic Article Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.
Academic Article Pim family kinases enhance tumor growth of prostate cancer cells.
Academic Article Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase.
Academic Article Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.
Academic Article Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.
Academic Article Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal.
Academic Article p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
Academic Article Regulation of Skp2 levels by the Pim-1 protein kinase.
Academic Article Sustained expression of the pim-1 kinase is specifically induced in myeloid cells by cytokines whose receptors are structurally related.
Academic Article The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.
Concept Oncogenes
Concept Proto-Oncogene Proteins c-pim-1
Concept Proto-Oncogenes
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-mos
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins
Academic Article Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis.
Academic Article Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue.
Academic Article Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer.
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  • Oncogenes