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The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4.
Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes.
High Levels of Extracellular Potassium Can Delay Myxoma Virus Replication by Preventing Release of Virions from the Endosomes.