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Proteomic assessment shows that many endoplasmic reticulum (ER)-resident proteins are targeted by N(epsilon)-lysine acetylation in the lumen of the organelle and predicts broad biological impact.
SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway.
Acetyl Coenzyme A
Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer.