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Endowed Chair, S.C. SmartState Endowed Chair in Cancer Stem Cell Biology and Therapy
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Hematopoietic Stem Cell Transplantation
Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice.
Tolerance induction between two different strains of parental mice prevents graft-versus-host disease in haploidentical hematopoietic stem cell transplantation to F1 mice.
T-Cell Metabolism in Hematopoietic Cell Transplantation.
Inhibition of the IRE-1a/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice.
The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease.
Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease.
STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function.
A single strain of Bacteroides fragilis protects gut integrity and reduces GVHD.
XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1a-Dependent Decay.
MicroRNA-31 regulates T-cell metabolism via HIF1a and promotes chronic GVHD pathogenesis in mice.
Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway.
S1P/S1PR1 signaling differentially regulates the allogeneic response of CD4 and CD8 T cells by modulating mitochondrial fission.
The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease.
The Absence of IL-12R?2 Expression on Recipient Nonhematopoietic Cells Diminishes Acute Graft-versus-Host Disease in the Gastrointestinal Tract.