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Application of a C. elegans dopamine neuron degeneration assay for the validation of potential Parkinson's disease genes.
VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease.
Caenorhabditis elegans as a model system for identifying effectors of a-synuclein misfolding and dopaminergic cell death associated with Parkinson's disease.
Modeling dopamine neuron degeneration in Caenorhabditis elegans.
Functional analysis of VPS41-mediated neuroprotection in Caenorhabditis elegans and mammalian models of Parkinson's disease.