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Ostrowski, Michael
One or more keywords matched the following items that are connected to Ostrowski, Michael
Item TypeName
Concept Disease Models, Animal
Concept Animals, Newborn
Concept Animals
Concept Mammary Neoplasms, Animal
Concept Mammary Glands, Animal
Concept Pregnancy, Animal
Concept Models, Animal
Academic Article Extra-embryonic function of Rb is essential for embryonic development and viability.
Academic Article CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.
Academic Article Direct evidence for epithelial-mesenchymal transitions in breast cancer.
Academic Article Tensor classification of N-point correlation function features for histology tissue segmentation.
Academic Article Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
Academic Article Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Academic Article Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis.
Academic Article An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
Academic Article Allele-specific tumor spectrum in pten knockin mice.
Academic Article E2f1-3 are critical for myeloid development.
Academic Article Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.
Academic Article Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Academic Article Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
Academic Article FGFR and PTEN signaling interact during lens development to regulate cell survival.
Academic Article Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
Academic Article Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
Academic Article Ets-2 interacts with co-repressor BS69 to repress target gene expression.
Academic Article Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.
Academic Article Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.
Academic Article MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells.
Academic Article RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment.
Academic Article MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
Academic Article Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.
Academic Article The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene.
Academic Article Inhibitor ?B kinase 2 is a myosin light chain kinase in vascular smooth muscle.
Academic Article Regulation of the murine TRACP gene promoter.
Academic Article Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover.
Academic Article Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Academic Article Transcription factor ATF3 links host adaptive response to breast cancer metastasis.
Academic Article The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts.
Academic Article Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Academic Article IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Academic Article Evidence that human haematopoietic stem cells (HSC) do not reside within the CD34+KIT- cell population.
Academic Article Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors.
Academic Article Cyclic AMP-dependent activation of Rap1b.
Academic Article Regulation of urokinase-type plasminogen activator gene transcription by macrophage colony-stimulating factor.
Academic Article Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling.
Academic Article The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.
Academic Article Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression.
Academic Article Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
Academic Article ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.
Academic Article Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis.
Academic Article A subpopulation of peritoneal macrophages form capillarylike lumens and branching patterns in vitro.
Academic Article A new role for OPG: putting RANKL in its place.
Academic Article Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.
Academic Article NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
Academic Article Cry protein crystals: a novel platform for protein delivery.
Academic Article The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).
Academic Article RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1.
Academic Article TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.
Academic Article The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor.
Academic Article Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model.
Academic Article Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks.
Academic Article Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.
Academic Article The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor.
Academic Article Loss of fibroblast HIF-1a accelerates tumorigenesis.
Academic Article Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.
Academic Article Non-nuclear oncogenes and the regulation of gene expression in transformed cells.
Academic Article Protein kinase C gamma expression mimics phorbol ester-induced transcriptional activation of a murine VL30 enhancer element.
Academic Article Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
Academic Article Analysis of the v-myb structural components important for transactivation of gene expression.
Academic Article The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.
Academic Article The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma.
Academic Article Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.
Academic Article Transcriptional activation of a conserved sequence element by ras requires a nuclear factor distinct from c-fos or c-jun.
Academic Article Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.
Academic Article Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
Academic Article The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling.
Academic Article Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.
Academic Article MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
Academic Article Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.
Academic Article ras oncogene activation of a VL30 transcriptional element is linked to transformation.
Academic Article The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts.
Academic Article The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.
Academic Article GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element.
Academic Article ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Academic Article E2f3 in tumor macrophages promotes lung metastasis.
Academic Article Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
Academic Article Transcriptional control of the expression of the c-fms gene encoding the receptor for macrophage colony-stimulating factor (CSF-1).
Academic Article Regulation of CSF-1 receptor expression.
Academic Article Negative regulation of transcription in vitro by a glucocorticoid response element is mediated by a trans-acting factor.
Academic Article Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
Academic Article Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.
Academic Article MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation.
Academic Article Rapid and selective alterations in the expression of cellular genes accompany conditional transcription of Ha-v-ras in NIH 3T3 cells.
Academic Article Setting Snail2's pace during EMT.
Academic Article Transcription factor ets-2 plays an important role in the pathogenesis of pulmonary fibrosis.
Academic Article A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation.
Academic Article Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells.
Academic Article Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation.
Academic Article A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene.
Academic Article Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.
Academic Article CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
Academic Article Control of interferon-tau gene expression by Ets-2.
Academic Article Involvement of Ets, rel and Sp1-like proteins in lipopolysaccharide-mediated activation of the HIV-1 LTR in macrophages.
Academic Article NF-?B signaling in fetal lung macrophages disrupts airway morphogenesis.
Academic Article Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
Academic Article Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt.
Academic Article Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling.
Academic Article Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
Academic Article Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.
Academic Article Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.
Academic Article NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.
Academic Article PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.
Academic Article TFEC is a macrophage-restricted member of the microphthalmia-TFE subfamily of basic helix-loop-helix leucine zipper transcription factors.
Academic Article Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members.
Academic Article Glucocorticoid regulation of transcription at an amplified, episomal promoter.
Academic Article Stromal PTEN determines mammary epithelial response to radiotherapy.
Academic Article Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Academic Article Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
Academic Article Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation.
Academic Article Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair.
Academic Article PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance.
Academic Article Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.
Academic Article Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
Academic Article Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.
Academic Article Nanofiber-expanded human CD34+ cells heal cutaneous wounds in streptozotocin-induced diabetic mice.
Academic Article Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Academic Article Modeling Human Cancer-induced Cachexia.
Academic Article Hepatocyte-specific PKC? deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis.
Academic Article Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.
Academic Article Targeting the KRAS a4-a5 allosteric interface inhibits pancreatic cancer tumorigenesis.
Academic Article Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain.
Academic Article Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
Academic Article PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
Academic Article The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Academic Article Role of hepatic PKC? in nutritional regulation of hepatic glycogen synthesis.
Academic Article STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Academic Article Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
Academic Article The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
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