Item Type | Name |
Concept
|
Muscle, Smooth, Vascular
|
Concept
|
Peyer's Patches
|
Concept
|
Genes, Lethal
|
Concept
|
RNA, Small Interfering
|
Concept
|
Receptors, Colony-Stimulating Factor
|
Concept
|
Neoplastic Stem Cells
|
Concept
|
Multigene Family
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
Genes, BRCA1
|
Concept
|
Genes, Tumor Suppressor
|
Concept
|
Oncogenes
|
Concept
|
Streptozocin
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Cell Survival
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Proto-Oncogenes
|
Concept
|
Operon
|
Concept
|
Genes, Dominant
|
Concept
|
Genes, Viral
|
Concept
|
Genes, bcl-1
|
Concept
|
Sirolimus
|
Concept
|
Computer Simulation
|
Concept
|
Sterol Regulatory Element Binding Protein 1
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
STAT5 Transcription Factor
|
Concept
|
Amino Acid Sequence
|
Concept
|
Stress, Physiological
|
Concept
|
Suppression, Genetic
|
Concept
|
Saccharomyces cerevisiae
|
Concept
|
Cohort Studies
|
Concept
|
Lac Operon
|
Concept
|
L-Selectin
|
Concept
|
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
|
Concept
|
S100 Proteins
|
Concept
|
Genome
|
Concept
|
Shc Signaling Adaptor Proteins
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Genes, jun
|
Concept
|
Cholesterol Side-Chain Cleavage Enzyme
|
Concept
|
Genes, APC
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Conserved Sequence
|
Concept
|
Growth Substances
|
Concept
|
Saposins
|
Concept
|
STAT Transcription Factors
|
Concept
|
Genes, ras
|
Concept
|
Organ Specificity
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
Concept
|
Retrospective Studies
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
Concept
|
Sequence Deletion
|
Concept
|
Consensus Sequence
|
Concept
|
Stem Cells
|
Concept
|
Species Specificity
|
Concept
|
Cell Separation
|
Concept
|
Genes, p53
|
Concept
|
Signal Transduction
|
Concept
|
Survival Rate
|
Concept
|
Genes, Regulator
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Transgenes
|
Concept
|
Hematopoietic Stem Cells
|
Concept
|
RNA, Small Nucleolar
|
Concept
|
Reactive Oxygen Species
|
Concept
|
Harvey murine sarcoma virus
|
Concept
|
Glycogen Synthase
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Myocytes, Smooth Muscle
|
Concept
|
Genes, Bacterial
|
Concept
|
Genes, Reporter
|
Concept
|
Glycogen Synthase Kinase 3
|
Concept
|
Down Syndrome
|
Concept
|
Survival Analysis
|
Concept
|
Sheep
|
Concept
|
Protein Stability
|
Concept
|
Scavenger Receptors, Class B
|
Concept
|
Sequence Alignment
|
Concept
|
Electrophoretic Mobility Shift Assay
|
Concept
|
Binding Sites
|
Concept
|
Saccharomyces cerevisiae Proteins
|
Concept
|
Nuclear Localization Signals
|
Concept
|
Spheroids, Cellular
|
Concept
|
Mice, SCID
|
Concept
|
Receptor, Macrophage Colony-Stimulating Factor
|
Concept
|
Mice, Inbred Strains
|
Concept
|
Genes, myc
|
Concept
|
DNA Breaks, Double-Stranded
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Neoplasm Staging
|
Concept
|
Antibody Specificity
|
Concept
|
Sequence Homology, Nucleic Acid
|
Concept
|
In Situ Hybridization
|
Concept
|
Stromal Cells
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Sp1 Transcription Factor
|
Concept
|
Macrophage Colony-Stimulating Factor
|
Concept
|
Genes, fms
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
Chorionic Gonadotropin, beta Subunit, Human
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Receptors, Scavenger
|
Concept
|
Structure-Activity Relationship
|
Concept
|
Skin
|
Concept
|
Gene Silencing
|
Concept
|
Base Sequence
|
Concept
|
Alleles
|
Concept
|
Mononuclear Phagocyte System
|
Concept
|
Muscle, Skeletal
|
Concept
|
Spermidine
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Molecular Sequence Data
|
Concept
|
Tumor Suppressor Proteins
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
Concept
|
Lymphocyte Subsets
|
Academic Article
|
CpG island methylation in a mouse model of lymphoma is driven by the genetic configuration of tumor cells.
|
Academic Article
|
Tensor classification of N-point correlation function features for histology tissue segmentation.
|
Academic Article
|
Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis.
|
Academic Article
|
Pten in stromal fibroblasts suppresses mammary epithelial tumours.
|
Academic Article
|
An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.
|
Academic Article
|
Allele-specific tumor spectrum in pten knockin mice.
|
Academic Article
|
E2f1-3 are critical for myeloid development.
|
Academic Article
|
Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution.
|
Academic Article
|
Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer.
|
Academic Article
|
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.
|
Academic Article
|
FGFR and PTEN signaling interact during lens development to regulate cell survival.
|
Academic Article
|
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia.
|
Academic Article
|
Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia.
|
Academic Article
|
Ets-2 interacts with co-repressor BS69 to repress target gene expression.
|
Academic Article
|
Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1.
|
Academic Article
|
Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.
|
Academic Article
|
MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells.
|
Academic Article
|
RAGE mediates S100A7-induced breast cancer growth and metastasis by modulating the tumor microenvironment.
|
Academic Article
|
MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
|
Academic Article
|
Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.
|
Academic Article
|
CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells.
|
Academic Article
|
The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene.
|
Academic Article
|
Inhibitor ?B kinase 2 is a myosin light chain kinase in vascular smooth muscle.
|
Academic Article
|
Regulation of the murine TRACP gene promoter.
|
Academic Article
|
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
|
Academic Article
|
Transcription factor ATF3 links host adaptive response to breast cancer metastasis.
|
Academic Article
|
The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts.
|
Academic Article
|
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
|
Academic Article
|
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
|
Academic Article
|
Evidence that human haematopoietic stem cells (HSC) do not reside within the CD34+KIT- cell population.
|
Academic Article
|
Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors.
|
Academic Article
|
The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation.
|
Academic Article
|
An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites.
|
Academic Article
|
Cyclic AMP-dependent activation of Rap1b.
|
Academic Article
|
Regulation of urokinase-type plasminogen activator gene transcription by macrophage colony-stimulating factor.
|
Academic Article
|
Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling.
|
Academic Article
|
The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.
|
Academic Article
|
Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression.
|
Academic Article
|
Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
|
Academic Article
|
ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.
|
Academic Article
|
Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis.
|
Academic Article
|
A subpopulation of peritoneal macrophages form capillarylike lumens and branching patterns in vitro.
|
Academic Article
|
A new role for OPG: putting RANKL in its place.
|
Academic Article
|
Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes.
|
Academic Article
|
NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
|
Academic Article
|
Cry protein crystals: a novel platform for protein delivery.
|
Academic Article
|
The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).
|
Academic Article
|
RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1.
|
Academic Article
|
TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.
|
Academic Article
|
The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor.
|
Academic Article
|
Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model.
|
Academic Article
|
Genetics and genomics of osteoclast differentiation: integrating cell signaling pathways and gene networks.
|
Academic Article
|
Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1.
|
Academic Article
|
The expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factor.
|
Academic Article
|
Loss of fibroblast HIF-1a accelerates tumorigenesis.
|
Academic Article
|
Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells.
|
Academic Article
|
Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant.
|
Academic Article
|
Non-nuclear oncogenes and the regulation of gene expression in transformed cells.
|
Academic Article
|
Protein kinase C gamma expression mimics phorbol ester-induced transcriptional activation of a murine VL30 enhancer element.
|
Academic Article
|
Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.
|
Academic Article
|
Analysis of the v-myb structural components important for transactivation of gene expression.
|
Academic Article
|
The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.
|
Academic Article
|
Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.
|
Academic Article
|
The ETS family of oncogenic transcription factors in solid tumours.
|
Academic Article
|
Transcriptional activation of a conserved sequence element by ras requires a nuclear factor distinct from c-fos or c-jun.
|
Academic Article
|
Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo.
|
Academic Article
|
Stromal PDGFR-a Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.
|
Academic Article
|
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2.
|
Academic Article
|
A nuclear factor that binds to ras-responsive enhancer elements is present in human tumor cells.
|
Academic Article
|
The transactivation potential of a c-Myc N-terminal region (residues 92-143) is regulated by growth factor/Ras signaling.
|
Academic Article
|
Defective co-activator recruitment in osteoclasts from microphthalmia-oak ridge mutant mice.
|
Academic Article
|
Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling.
|
Academic Article
|
MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
|
Academic Article
|
Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.
|
Academic Article
|
ras oncogene activation of a VL30 transcriptional element is linked to transformation.
|
Academic Article
|
GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element.
|
Academic Article
|
ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
|
Academic Article
|
e-Science, caGrid, and Translational Biomedical Research.
|
Academic Article
|
IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-?B.
|
Academic Article
|
Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways.
|
Academic Article
|
E2f3 in tumor macrophages promotes lung metastasis.
|
Academic Article
|
Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer.
|
Academic Article
|
Transcriptional control of the expression of the c-fms gene encoding the receptor for macrophage colony-stimulating factor (CSF-1).
|
Academic Article
|
ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis.
|
Academic Article
|
Regulation of CSF-1 receptor expression.
|
Academic Article
|
Negative regulation of transcription in vitro by a glucocorticoid response element is mediated by a trans-acting factor.
|
Academic Article
|
Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein.
|
Academic Article
|
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
|
Academic Article
|
PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway.
|
Academic Article
|
Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.
|
Academic Article
|
Rapid and selective alterations in the expression of cellular genes accompany conditional transcription of Ha-v-ras in NIH 3T3 cells.
|
Academic Article
|
Setting Snail2's pace during EMT.
|
Academic Article
|
A mouse model of yellow fluorescent protein (YFP) expression in hematopoietic cells to assess leukocyte-endothelial interactions in the microcirculation.
|
Academic Article
|
Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells.
|
Academic Article
|
Genomic alterations in tumor stroma.
|
Academic Article
|
Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation.
|
Academic Article
|
A central role for Ets-2 in the transcriptional regulation and cyclic adenosine 5'-monophosphate responsiveness of the human chorionic gonadotropin-beta subunit gene.
|
Academic Article
|
Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.
|
Academic Article
|
Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry.
|
Academic Article
|
A hedgehog pathway-dependent gene signature is associated with poor clinical outcomes in Luminal A breast cancer.
|
Academic Article
|
CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth.
|
Academic Article
|
Control of interferon-tau gene expression by Ets-2.
|
Academic Article
|
Involvement of Ets, rel and Sp1-like proteins in lipopolysaccharide-mediated activation of the HIV-1 LTR in macrophages.
|
Academic Article
|
NF-?B signaling in fetal lung macrophages disrupts airway morphogenesis.
|
Academic Article
|
Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent.
|
Academic Article
|
Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
|
Academic Article
|
Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt.
|
Academic Article
|
Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling.
|
Academic Article
|
Trisomy represses Apc(Min)-mediated tumours in mouse models of Down's syndrome.
|
Academic Article
|
Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments.
|
Academic Article
|
Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression.
|
Academic Article
|
SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.
|
Academic Article
|
Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.
|
Academic Article
|
NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.
|
Academic Article
|
PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter.
|
Academic Article
|
TFEC is a macrophage-restricted member of the microphthalmia-TFE subfamily of basic helix-loop-helix leucine zipper transcription factors.
|
Academic Article
|
Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members.
|
Academic Article
|
Glucocorticoid regulation of transcription at an amplified, episomal promoter.
|
Academic Article
|
Stromal PTEN determines mammary epithelial response to radiotherapy.
|
Academic Article
|
Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
|
Academic Article
|
Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.
|
Academic Article
|
Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair.
|
Academic Article
|
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
|
Academic Article
|
Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.
|
Academic Article
|
Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition.
|
Academic Article
|
Nanofiber-expanded human CD34+ cells heal cutaneous wounds in streptozotocin-induced diabetic mice.
|
Academic Article
|
Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
|
Academic Article
|
Modeling Human Cancer-induced Cachexia.
|
Academic Article
|
PTEN in the Stroma.
|
Academic Article
|
Hepatocyte-specific PKC? deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis.
|
Academic Article
|
Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.
|
Academic Article
|
Targeting the KRAS a4-a5 allosteric interface inhibits pancreatic cancer tumorigenesis.
|
Academic Article
|
Stromal Platelet-Derived Growth Factor Receptor-? Signaling Promotes Breast Cancer Metastasis in the Brain.
|
Academic Article
|
Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
|
Concept
|
Pancreatic Stellate Cells
|
Concept
|
Transcriptome
|
Concept
|
Snail Family Transcription Factors
|
Concept
|
Src Homology 2 Domain-Containing, Transforming Protein 1
|
Concept
|
Glycogen Synthase Kinase 3 beta
|
Concept
|
Synthetic Lethal Mutations
|
Concept
|
Smoothened Receptor
|
Concept
|
S100 Calcium Binding Protein A7
|
Academic Article
|
PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
|
Academic Article
|
The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
|
Academic Article
|
Defining the Tumor Microenvironment by Integration of Immunohistochemistry and Extracellular Matrix Targeted Imaging Mass Spectrometry.
|
Academic Article
|
Role of hepatic PKC? in nutritional regulation of hepatic glycogen synthesis.
|
Academic Article
|
STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
|
Academic Article
|
PTEN in cancer associated fibroblasts.
|
Academic Article
|
Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.
|
Academic Article
|
Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro.
|
Academic Article
|
The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
|
Academic Article
|
Cancer cachexia: involvement of an expanding macroenvironment.
|