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O'Bryan, John
One or more keywords matched the following items that are connected to O'Bryan, John
Item TypeName
Concept Oncogene Proteins, Fusion
Concept Proto-Oncogene Protein c-fli-1
Concept Oncogene Protein p21(ras)
Concept Oncogene Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-vav
Concept Proto-Oncogene Proteins c-cbl
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins
Academic Article axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
Academic Article Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis.
Academic Article The transforming receptor tyrosine kinase, Axl, is post-translationally regulated by proteolytic cleavage.
Academic Article Rek, a gene expressed in retina and brain, encodes a receptor tyrosine kinase of the Axl/Tyro3 family.
Academic Article The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor.
Academic Article Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells.
Academic Article Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity.
Academic Article Intersectin, an adaptor protein involved in clathrin-mediated endocytosis, activates mitogenic signaling pathways.
Academic Article Intersectin activates Ras but stimulates transcription through an independent pathway involving JNK.
Academic Article The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors.
Academic Article Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.
Academic Article Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway.
Academic Article Intersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interaction.
Academic Article A new dimension to Ras function: a novel role for nucleotide-free Ras in Class II phosphatidylinositol 3-kinase beta (PI3KC2?) regulation.
Academic Article Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase.
Academic Article Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2?) isoform contributes to neuroblastoma tumorigenesis.
Academic Article Intersectin scaffold proteins and their role in cell signaling and endocytosis.
Academic Article Targeting the a4-a5 interface of RAS results in multiple levels of inhibition.
Academic Article Akt2 (Protein Kinase B Beta) Stabilizes ATP7A, a Copper Transporter for Extracellular Superoxide Dismutase, in Vascular Smooth Muscle: Novel Mechanism to Limit Endothelial Dysfunction in Type 2 Diabetes Mellitus.
Academic Article Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Academic Article Targeting the KRAS a4-a5 allosteric interface inhibits pancreatic cancer tumorigenesis.
Academic Article Inhibition of RAS: proven and potential vulnerabilities.
Academic Article Inhibition of RAS-driven signaling and tumorigenesis with a pan-RAS monobody targeting the Switch I/II pocket.
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  • Oncogene Proteins