Item Type | Name |
Academic Article
|
ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression.
|
Academic Article
|
beta-Adrenergic and endothelin receptor interaction in dilated human cardiomyopathic myocardium.
|
Academic Article
|
Temporal endothelin dynamics of the myocardial interstitium and systemic circulation in cardiopulmonary bypass.
|
Academic Article
|
Potential role of endothelin receptor antagonists in the setting of cardiopulmonary bypass: relevance to myocardial performance.
|
Concept
|
Disease Models, Animal
|
Concept
|
Animals
|
Concept
|
Animal Feed
|
Concept
|
Behavior, Animal
|
Concept
|
Models, Animal
|
Concept
|
Sexual Behavior, Animal
|
Academic Article
|
A review of endothelin and hypertension in African-American individuals.
|
Academic Article
|
Endothelin-1 and endothelin receptor antagonists as potential cardiovascular therapeutic agents.
|
Academic Article
|
Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation.
|
Academic Article
|
Nuclear localization of endothelin-converting enzyme-1: subisoform specificity.
|
Academic Article
|
Neuroprotection by tempol in a model of iron-induced oxidative stress in acute ischemic stroke.
|
Academic Article
|
Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition-induced hypertension.
|
Academic Article
|
Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1.
|
Academic Article
|
Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.
|
Academic Article
|
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection.
|
Academic Article
|
Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation to vessel size.
|
Academic Article
|
Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization.
|
Academic Article
|
Microvascular versus macrovascular dysfunction in type 2 diabetes: differences in contractile responses to endothelin-1.
|
Academic Article
|
Differential effects of ET(A) and ET(B) receptor antagonism on oxidative stress in type 2 diabetes.
|
Academic Article
|
Evidence for vasculoprotective effects of ETB receptors in resistance artery remodeling in diabetes.
|
Academic Article
|
Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 diabetes.
|
Academic Article
|
Effect of chronic and selective endothelin receptor antagonism on microvascular function in type 2 diabetes.
|
Academic Article
|
DOCA-salt treatment enhances responses to endothelin-1 in murine corpus cavernosum.
|
Academic Article
|
Impaired insulin-mediated vasorelaxation in a nonobese model of type 2 diabetes: role of endothelin-1.
|
Academic Article
|
Activation of the ET-1/ETA pathway contributes to erectile dysfunction associated with mineralocorticoid hypertension.
|
Academic Article
|
Differential effects of diet-induced dyslipidemia and hyperglycemia on mesenteric resistance artery structure and function in type 2 diabetes.
|
Academic Article
|
Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway.
|
Academic Article
|
Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1.
|
Academic Article
|
Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature.
|
Academic Article
|
O-GlcNAcylation contributes to augmented vascular reactivity induced by endothelin 1.
|
Academic Article
|
Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177.
|
Academic Article
|
Endothelial endothelin B receptor-mediated prevention of cerebrovascular remodeling is attenuated in diabetes because of up-regulation of smooth muscle endothelin receptors.
|
Academic Article
|
Internal pudendal artery from type 2 diabetic female rats demonstrate elevated endothelin-1-mediated constriction.
|
Academic Article
|
Comparison of selective versus dual endothelin receptor antagonism on cerebrovascular dysfunction in diabetes.
|
Academic Article
|
The effect of endothelin receptor A antagonism on basilar artery endothelium-dependent relaxation after ischemic stroke.
|
Academic Article
|
Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke.
|
Academic Article
|
Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes.
|
Academic Article
|
Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats.
|
Academic Article
|
Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke.
|
Academic Article
|
Augmented dilation to nitric oxide in uterine arteries from rats with type 2 diabetes: implications for vascular adaptations to pregnancy.
|
Academic Article
|
Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes.
|
Academic Article
|
Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control.
|
Academic Article
|
Reply to "Letter to the editor: 'Targeting cerebrovascular myogenic dysfunction in stroke'".
|
Academic Article
|
SOD1 overexpression prevents acute hyperglycemia-induced cerebral myogenic dysfunction: relevance to contralateral hemisphere and stroke outcomes.
|
Academic Article
|
Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes.
|
Academic Article
|
The contribution of Toll-like receptors to placental inflammation in diet-induced maternal obesity.
|
Academic Article
|
Linagliptin reduces effects of ET-1 and TLR2-mediated cerebrovascular hyperreactivity in diabetes.
|
Academic Article
|
High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity?
|
Academic Article
|
Impact of Metabolic Diseases on Cerebral Circulation: Structural and Functional Consequences.
|
Academic Article
|
Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4.
|
Academic Article
|
Endothelin and diabetic complications: a brain-centric view.
|
Academic Article
|
Endothelin-1 inhibition improves the mBDNF/proBDNF ratio in endothelial cells and HT22 neurons under high glucose/palmitate growth conditions.
|
Academic Article
|
Poststroke cognitive impairment and hippocampal neurovascular remodeling: the impact of diabetes and sex.
|
Academic Article
|
Brain Vasculature and Cognition.
|
Academic Article
|
NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia.
|
Academic Article
|
Angiotensin II type 2 receptor stimulation with compound 21 improves neurological function after stroke in female rats: a pilot study.
|
Academic Article
|
Early effects of high-fat diet on neurovascular function and focal ischemic brain injury.
|
Academic Article
|
Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke.
|
Academic Article
|
Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes.
|
Academic Article
|
Linagliptin treatment improves cerebrovascular function and remodeling and restores reduced cerebral perfusion in Type 2 diabetes.
|
Academic Article
|
Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle.
|
Academic Article
|
Vascularization pattern after ischemic stroke is different in control versus diabetic rats: relevance to stroke recovery.
|
Academic Article
|
Cerebrovascular complications of diabetes: focus on cognitive dysfunction.
|
Academic Article
|
Comparative analysis of the neurovascular injury and functional outcomes in experimental stroke models in diabetic Goto-Kakizaki rats.
|
Academic Article
|
Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodeling.
|
Academic Article
|
Endothelin-1-mediated cerebrovascular remodeling is not associated with increased ischemic brain injury in diabetes.
|
Academic Article
|
Post-stroke neovascularization and functional outcomes differ in diabetes depending on severity of injury and sex: Potential link to hemorrhagic transformation.
|
Academic Article
|
Cerebral myogenic reactivity and blood flow in type 2 diabetic rats: role of peroxynitrite in hypoxia-mediated loss of myogenic tone.
|
Academic Article
|
TLR2 knockout protects against diabetes-mediated changes in cerebral perfusion and cognitive deficits.
|
Academic Article
|
Mechanisms of acute neurovascular protection with AT1 blockade after stroke: Effect of prestroke hypertension.
|
Academic Article
|
Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition.
|
Academic Article
|
Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells.
|
Academic Article
|
Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes.
|
Academic Article
|
Low-dose candesartan enhances molecular mediators of neuroplasticity and subsequent functional recovery after ischemic stroke in rats.
|
Academic Article
|
Neurovascular protection in voltage-gated proton channel Hv1 knock-out rats after ischemic stroke: interaction with Na+ /H+ exchanger-1 antagonism.
|
Academic Article
|
Relationship of endothelin-1 and NLRP3 inflammasome activation in HT22 hippocampal cells in diabetes.
|
Academic Article
|
Adaptive cerebral neovascularization in a model of type 2 diabetes: relevance to focal cerebral ischemia.
|
Academic Article
|
Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.
|
Academic Article
|
Inflammation within the neurovascular unit: Focus on microglia for stroke injury and recovery.
|
Academic Article
|
Inhibition of Ephrin-B2 in brain pericytes decreases cerebral pathological neovascularization in diabetic rats.
|
Academic Article
|
Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study.
|
Academic Article
|
RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial.
|
Academic Article
|
Silencing VEGF-B Diminishes the Neuroprotective Effect of Candesartan Treatment After Experimental Focal Cerebral Ischemia.
|
Academic Article
|
Within the Brain: The Renin Angiotensin System.
|
Academic Article
|
Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.
|
Academic Article
|
Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals - A randomized double- blind pre-clinical study.
|
Academic Article
|
Peroxynitrite-Induced Tyrosine Nitration Contributes to Matrix Metalloprotease-3 Activation: Relevance to Hyperglycemic Ischemic Brain Injury and Tissue Plasminogen Activator.
|
Academic Article
|
Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury.
|
Academic Article
|
Enhanced VEGF signalling mediates cerebral neovascularisation via downregulation of guidance protein ROBO4 in a rat model of diabetes.
|
Academic Article
|
Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes.
|
Academic Article
|
Diabetes-mediated middle cerebral artery remodeling is restored by linagliptin: Interaction with the vascular smooth muscle cell endothelin system.
|
Academic Article
|
Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke.
|
Academic Article
|
Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke.
|
Academic Article
|
Linagliptin attenuates diabetes-induced cerebral pathological neovascularization in a blood glucose-independent manner: Potential role of ET-1.
|
Academic Article
|
The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGF?-induced pulmonary fibrosis.
|
Academic Article
|
Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period.
|
Academic Article
|
Comparative Analysis of Different Methods of Ischemia/Reperfusion in Hyperglycemic Stroke Outcomes: Interaction with tPA.
|
Academic Article
|
Remote ischemic postconditioning: harnessing endogenous protection in a murine model of vascular cognitive impairment.
|
Academic Article
|
Deletion of thioredoxin interacting protein (TXNIP) augments hyperoxia-induced vaso-obliteration in a mouse model of oxygen induced-retinopathy.
|
Academic Article
|
Cerebrovasculoprotective effects of azilsartan medoxomil in diabetes.
|
Academic Article
|
Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.
|
Academic Article
|
Candesartan induces a prolonged proangiogenic effect and augments endothelium-mediated neuroprotection after oxygen and glucose deprivation: role of vascular endothelial growth factors A and B.
|
Academic Article
|
Hyperglycemia, acute ischemic stroke, and thrombolytic therapy.
|
Academic Article
|
Cerebral neovascularization in diabetes: implications for stroke recovery and beyond.
|
Academic Article
|
Remote ischemic perconditioning is effective after embolic stroke in ovariectomized female mice.
|
Academic Article
|
Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet.
|
Academic Article
|
Candesartan reduces the hemorrhage associated with delayed tissue plasminogen activator treatment in rat embolic stroke.
|
Academic Article
|
Recommendations for preclinical research in hemorrhagic transformation.
|
Academic Article
|
Endothelial stromelysin1 regulation by the forkhead box-O transcription factors is crucial in the exudative phase of acute lung injury.
|
Academic Article
|
Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice.
|
Academic Article
|
Oxidative stress and cardiovascular disease: antioxidants and unresolved issues.
|
Academic Article
|
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke.
|
Academic Article
|
Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke.
|
Academic Article
|
Blood pressure lowering after experimental cerebral ischemia provides neurovascular protection.
|
Academic Article
|
Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke.
|
Academic Article
|
Diet-induced obesity causes cerebral vessel remodeling and increases the damage caused by ischemic stroke.
|
Academic Article
|
Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats.
|
Academic Article
|
Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential.
|
Academic Article
|
Dual endothelin receptor antagonism prevents remodeling of resistance arteries in diabetes.
|
Academic Article
|
Endothelin-1 and diabetic complications: focus on the vasculature.
|
Academic Article
|
Effects of spironolactone on cerebral vessel structure in rats with sustained hypertension.
|
Academic Article
|
Cerebrovascular complications of diabetes: focus on stroke.
|
Academic Article
|
Enhanced cerebral but not peripheral angiogenesis in the Goto-Kakizaki model of type 2 diabetes involves VEGF and peroxynitrite signaling.
|
Academic Article
|
AT1 receptor antagonism is proangiogenic in the brain: BDNF a novel mediator.
|
Academic Article
|
Peroxynitrite mediates testosterone-induced vasodilation of microvascular resistance vessels.
|
Academic Article
|
Cerebral neovascularization and remodeling patterns in two different models of type 2 diabetes.
|
Academic Article
|
Response to letter regarding article, "Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type".
|
Academic Article
|
Nox2-derived superoxide contributes to cerebral vascular dysfunction in diet-induced obesity.
|
Grant
|
Progressive Post Stroke Cognitive Impairment:Mechanisms & Intervention
|
Grant
|
Vascular Injury and Recovery in Diabetic Ischemic Stroke
|
Academic Article
|
Diabetic rats are more susceptible to cognitive decline in a model of microemboli-mediated vascular contributions to cognitive impairment and dementia.
|
Academic Article
|
Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis.
|
Academic Article
|
Diabetes-related sex differences in the brain endothelin system following ischemia in vivo and in human brain endothelial cells in vitro.
|
Academic Article
|
Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke.
|
Academic Article
|
Endothelin-1 (ET-1) promotes a proinflammatory microglia phenotype in diabetic conditions.
|
Academic Article
|
Delayed Administration of Angiotensin Receptor (AT2R) Agonist C21 Improves Survival and Preserves Sensorimotor Outcomes in Female Diabetic Rats Post-Stroke through Modulation of Microglial Activation.
|
Academic Article
|
Stroke promotes the development of brain atrophy and delayed cell death in hypertensive rats.
|
Academic Article
|
Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke.
|
Academic Article
|
Impact of diabetes and ischemic stroke on the cerebrovasculature: A female perspective.
|
Academic Article
|
Contralesional angiotensin type 2 receptor activation contributes to recovery in experimental stroke.
|
Academic Article
|
Magnetic resonance imaging reveals microemboli-mediated pathological changes in brain microstructure in diabetic rats: relevance to vascular cognitive impairment/dementia.
|
Academic Article
|
Vascular contributions to cognitive impairment/dementia in diabetes: role of endothelial cells and pericytes.
|
Academic Article
|
Cerebral microvascular matrix metalloproteinase-3 (MMP3) contributes to vascular injury after stroke in female diabetic rats.
|
Academic Article
|
Deferoxamine prevents poststroke memory impairment in female diabetic rats: potential links to hemorrhagic transformation and ferroptosis.
|
Academic Article
|
Acute Ischemic Stroke by Middle Cerebral Artery Occlusion in Rat Models of Diabetes: Importance of Pre-op and Post-op Care, Severity of Hyperglycemia, and Sex.
|