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Gan, Wenjian
One or more keywords matched the following items that are connected to Gan, Wenjian
Item TypeName
Concept Oncogene Proteins, Fusion
Concept Oncogene Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Oncogene Protein v-akt
Concept Proto-Oncogene Proteins p21(ras)
Academic Article Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.
Academic Article Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Academic Article Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.
Academic Article Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF.
Academic Article PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.
Academic Article Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Academic Article pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
Academic Article TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.
Academic Article The p85 isoform of the kinase S6K1 functions as a secreted oncoprotein to facilitate cell migration and tumor growth.
Academic Article AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions.
Academic Article PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.
Academic Article Genetic fusions favor tumorigenesis through degron loss in oncogenes.
Academic Article DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway.
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  • Oncogene Proteins