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Roninson, Igor
One or more keywords matched the following items that are connected to Roninson, Igor
Item TypeName
Concept Cell Line, Tumor
Academic Article Analysis of gene amplification in human tumor cell lines.
Academic Article Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1.
Academic Article Proteomic analysis of factors released from p21-overexpressing tumour cells.
Academic Article Agonist and antagonist of retinoic acid receptors cause similar changes in gene expression and induce senescence-like growth arrest in MCF-7 breast carcinoma cells.
Academic Article Cell cycle arrest drastically extends the duration of gene silencing after transient expression of short hairpin RNA.
Academic Article p21 (CDKN1A) is a negative regulator of p53 stability.
Academic Article Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro.
Academic Article Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing.
Academic Article Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ? 2 renders tumor cells dependent on its paralogous gene COPZ1.
Academic Article Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21.
Academic Article Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Academic Article Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.
Academic Article Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.
Academic Article Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer.
Academic Article CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.
Academic Article Identifying Cancers Impacted by CDK8/19.
Academic Article The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs.
Academic Article A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.
Academic Article Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in?vitro and in?vivo.
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  • Cell Line Tumor