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Roninson, Igor
One or more keywords matched the following items that are connected to
Roninson, Igor
Item Type
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Concept
Doxorubicin
Academic Article
The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.
Academic Article
An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene.
Academic Article
The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.
Academic Article
Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification.
Academic Article
Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells.
Academic Article
Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA.
Academic Article
Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene.
Academic Article
Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells.
Academic Article
Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function.
Academic Article
Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis.
Academic Article
Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1.
Academic Article
p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
Academic Article
p21 (CDKN1A) is a negative regulator of p53 stability.
Academic Article
A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents.
Academic Article
Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs.
Academic Article
A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication.
Academic Article
Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent.
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Doxorubicin