| Item Type | Name |
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Concept
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Membrane Glycoproteins
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Concept
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Glycoproteins
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Academic Article
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The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo.
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Academic Article
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Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.
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Academic Article
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Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas.
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Academic Article
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Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes.
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Academic Article
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Activation of MDR1 (P-glycoprotein) gene expression in human cells by protein kinase C agonists.
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Academic Article
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From amplification to function: the case of the MDR1 gene.
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Academic Article
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Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis.
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Academic Article
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Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection.
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Academic Article
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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells.
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Academic Article
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Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.
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Academic Article
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Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.
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Academic Article
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Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein.
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Academic Article
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Structure and expression of the human MDR (P-glycoprotein) gene family.
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Academic Article
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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.
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Academic Article
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The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.
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Academic Article
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Molecular mechanism of multidrug resistance in tumor cells.
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Academic Article
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Detection of multidrug resistance markers, P-glycoprotein and mdr1 mRNA, in human leukemia cells.
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Academic Article
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An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene.
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Academic Article
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Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators.
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Academic Article
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Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs.
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Academic Article
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Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines.
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Academic Article
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Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein.
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Academic Article
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MDR-1 expression in metastatic malignant melanoma.
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Academic Article
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P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake.
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Academic Article
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Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate.
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Academic Article
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Monoclonal antibodies against P-glycoprotein, an MDR1 gene product, inhibit interleukin-2 release from PHA-activated lymphocytes.
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Academic Article
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Inhibition of cytarabine-induced MDR1 (P-glycoprotein) gene activation in human tumor cells by fatty acid-polyethylene glycol-fatty acid diesters, novel inhibitors of P-glycoprotein function.
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Academic Article
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P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity.
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Academic Article
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Isolation of altered-function mutants and genetic suppressor elements of multidrug transporter P-glycoprotein by expression selection from retroviral libraries.
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Academic Article
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Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
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Academic Article
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Effects of the multidrug transporter P-glycoprotein on cellular responses to ionizing radiation.
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Academic Article
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Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein.
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Academic Article
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Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity.
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Academic Article
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P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation.
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Academic Article
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Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein.
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