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The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity.
Anti-biofilm compounds derived from marine sponges.
Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems.
Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent.
Chemical shift assignments and secondary structure prediction of the master biofilm regulator, SinR, from Bacillus subtilis.
Membrane-permeabilizing activity of reverse-amide 2-aminoimidazole antibiofilm agents against Acinetobacter baumannii.
Teaching old drugs new tricks: Addressing resistance in Francisella.
Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections.
Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds.
The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production.
Acinetobacter baumannii Regulates Its Stress Responses via the BfmRS Two-Component Regulatory System.
Inhibition and dispersion of proteobacterial biofilms.
Control of bacterial biofilms with marine alkaloid derivatives.
Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents.
Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms.
The Biofilm Regulatory Network from Bacillus subtilis: A Structure-Function Analysis.