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Wyatt, Michael
One or more keywords matched the following items that are connected to Wyatt, Michael
Item TypeName
Concept Cell Cycle Proteins
Concept Cell Cycle
Academic Article Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype.
Academic Article Involvement of base excision repair in response to therapy targeted at thymidylate synthase.
Academic Article Uracil incorporation into genomic DNA does not predict toxicity caused by chemotherapeutic inhibition of thymidylate synthase.
Academic Article Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.
Academic Article PLK1 as an oncology target: current status and future potential.
Academic Article Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC.
Academic Article SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress.
Academic Article Current assessment of polo-like kinases as anti-tumor drug targets.
Academic Article Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity.
Academic Article Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor.
Concept Cell Cycle Checkpoints
Academic Article Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells.
Academic Article Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE.
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  • Cell Cycle