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Cardiac to cancer: connecting connexins to clinical opportunity.
Targeting connexin 43 with a-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1.
Connexin 43, breast cancer tumor suppressor: Missed connections?
The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial.
Topical administration of a connexin43-based peptide augments healing of chronic neuropathic diabetic foot ulcers: A multicenter, randomized trial.
A Multicenter Randomized Controlled Trial Evaluating a Cx43-Mimetic Peptide in Cutaneous Scarring.
Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, aCT1, reduces VEGF-dependent RPE pathophysiology.
Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics.
Connexin 43-Based Therapeutics for Dermal Wound Healing.
Development of PLGA nanoparticles for sustained release of a connexin43 mimetic peptide to target glioblastoma cells.
The connexin 43 carboxyl terminal mimetic peptide aCT1 prompts differentiation of a collagen scar matrix in humans resembling unwounded skin.
Connexin 43 confers chemoresistance through activating PI3K.