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McInnes, Campbell
One or more keywords matched the following items that are connected to McInnes, Campbell
Item TypeName
Concept Cyclin-Dependent Kinase 8
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Cyclin-Dependent Kinase 2
Concept Cyclin-Dependent Kinase 4
Concept Cyclin-Dependent Kinase 9
Concept Cyclin-Dependent Kinase Inhibitor p27
Academic Article 2-Anilino-4-(thiazol-5-yl)pyrimidine CDK inhibitors: synthesis, SAR analysis, X-ray crystallography, and biological activity.
Academic Article Structural determinants of CDK4 inhibition and design of selective ATP competitive inhibitors.
Academic Article Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes.
Academic Article Strategies for the design of potent and selective kinase inhibitors.
Academic Article Protein structures in virtual screening: a case study with CDK2.
Academic Article Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design.
Academic Article REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors.
Academic Article Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.
Academic Article Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors.
Academic Article Structural and functional analysis of cyclin D1 reveals p27 and substrate inhibitor binding requirements.
Academic Article Fragment based discovery of arginine isosteres through REPLACE: towards non-ATP competitive CDK inhibitors.
Academic Article Benzamide capped peptidomimetics as non-ATP competitive inhibitors of CDK2 using the REPLACE strategy.
Academic Article A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.
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  • Cyclin Dependent Kinase 8