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McInnes, Campbell
One or more keywords matched the following items that are connected to McInnes, Campbell
Item TypeName
Academic Article Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
Concept Proto-Oncogene Proteins c-pim-1
Concept Proto-Oncogene Proteins B-raf
Concept Proto-Oncogene Proteins c-mdm2
Concept Proto-Oncogene Proteins
Academic Article Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype.
Academic Article Structural determinants of CDK4 inhibition and design of selective ATP competitive inhibitors.
Academic Article Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding.
Academic Article Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance.
Academic Article PLK1 as an oncology target: current status and future potential.
Academic Article Current assessment of polo-like kinases as anti-tumor drug targets.
Academic Article The Meisenheimer Complex as a Paradigm in Drug Discovery: Reversible Covalent Inhibition through C67 of the ATP Binding Site of PLK1.
Academic Article Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.
Academic Article Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor.
Academic Article Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells.
Academic Article Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE.
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  • Oncogenes