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McInnes, Campbell
One or more keywords matched the following items that are connected to McInnes, Campbell
Item TypeName
Academic Article Calpain 10 homology modeling with CYGAK and increased lipophilicity leads to greater potency and efficacy in cells.
Concept Peptides
Concept Intracellular Signaling Peptides and Proteins
Concept Peptides, Cyclic
Academic Article Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype.
Academic Article Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange.
Academic Article Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes.
Academic Article Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design.
Academic Article Strategies for the design of potent and selective kinase inhibitors.
Academic Article REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors.
Academic Article Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.
Academic Article Iterative conversion of cyclin binding groove peptides into druglike CDK inhibitors with antitumor activity.
Academic Article Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors.
Academic Article Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.
Academic Article Peptidomimetic design of CDK inhibitors targeting the recruitment site of the cyclin subunit.
Academic Article Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor.
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  • Peptides