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Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types.
Host resistance influences patterns of experimental viral adaptation and virulence evolution.
Serial infection of diverse host (Mus) genotypes rapidly impedes pathogen fitness and virulence.
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.
Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition.
Host Pathogen Interactions