Item Type | Name |
Concept
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Disease Models, Animal
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Concept
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Animals, Newborn
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Concept
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Animals
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Concept
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Hepatitis, Animal
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Concept
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Pregnancy, Animal
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Academic Article
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Bryostatin-1 enhances the maturation and antigen-presenting ability of murine and human dendritic cells.
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Academic Article
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Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappaB and expression of Fas ligand in thymic stromal cells and consequent apoptosis in T cells.
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Academic Article
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Role of dioxin response element and nuclear factor-kappaB motifs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated regulation of Fas and Fas ligand expression.
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Academic Article
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Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor.
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Academic Article
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Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells.
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Academic Article
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Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells.
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Academic Article
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CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation.
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Academic Article
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Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis.
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Academic Article
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American ginseng suppresses inflammation and DNA damage associated with mouse colitis.
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Academic Article
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Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis.
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Academic Article
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American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells.
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Academic Article
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Cannabinoids as novel anti-inflammatory drugs.
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Academic Article
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Taming the beast within: resveratrol suppresses colitis and prevents colon cancer.
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Academic Article
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Stem cells as potential therapeutic targets for inflammatory bowel disease.
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Academic Article
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Do cannabinoids have a therapeutic role in transplantation?
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Academic Article
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Resveratrol (3,5,4'-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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Academic Article
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Bryostatin-1, a naturally occurring antineoplastic agent, acts as a Toll-like receptor 4 (TLR-4) ligand and induces unique cytokines and chemokines in dendritic cells.
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Academic Article
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Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties.
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Academic Article
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Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol.
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Academic Article
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Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-?B.
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Academic Article
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Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: evidence from an experimental murine model.
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Academic Article
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Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice.
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Academic Article
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Perinatal exposure to ?9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens.
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Academic Article
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Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis.
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Academic Article
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Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis.
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Academic Article
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Alternative medicines as emerging therapies for inflammatory bowel diseases.
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Academic Article
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Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.
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Academic Article
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs.
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Academic Article
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Prenatal exposure to TCDD triggers significant modulation of microRNA expression profile in the thymus that affects consequent gene expression.
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Academic Article
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MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis.
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Academic Article
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Indoles mitigate the development of experimental autoimmune encephalomyelitis by induction of reciprocal differentiation of regulatory T cells and Th17 cells.
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Academic Article
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Leptin antagonist ameliorates chronic colitis in IL-10?/? mice.
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Academic Article
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The emerging role of leptin antagonist as potential therapeutic option for inflammatory bowel disease.
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Academic Article
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Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by ?9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein a by microRNA-690.
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Academic Article
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The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment.
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Academic Article
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Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1.
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Academic Article
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Histone modifications are associated with ?9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses.
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Academic Article
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miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses.
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Academic Article
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Expression, regulation and function of microRNAs in multiple sclerosis.
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Academic Article
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Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid.
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Academic Article
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Estrogen receptor agonists for attenuation of neuroinflammation and neurodegeneration.
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Academic Article
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Exposure to diethylstilbestrol during pregnancy modulates microRNA expression profile in mothers and fetuses reflecting oncogenic and immunological changes.
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Academic Article
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Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor ? in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo.
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Academic Article
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Apigenin, a Natural Flavonoid, Attenuates EAE Severity Through the Modulation of Dendritic Cell and Other Immune Cell Functions.
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Academic Article
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Dietary Indoles Suppress Delayed-Type Hypersensitivity by Inducing a Switch from Proinflammatory Th17 Cells to Anti-Inflammatory Regulatory T Cells through Regulation of MicroRNA.
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Academic Article
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Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation.
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Academic Article
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The protective effects of resveratrol on social stress-induced cytokine release and depressive-like behavior.
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Academic Article
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Altered gut microbiome in a mouse model of Gulf War Illness causes neuroinflammation and intestinal injury via leaky gut and TLR4 activation.
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Academic Article
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CD44 deletion leading to attenuation of experimental autoimmune encephalomyelitis results from alterations in gut microbiome in mice.
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Academic Article
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Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity.
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Academic Article
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MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target.
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Academic Article
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An endogenous aryl hydrocarbon receptor ligand, ITE, induces regulatory T cells and ameliorates experimental colitis.
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Academic Article
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Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness.
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Academic Article
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Genistein induces macrophage polarization and systemic cytokine to ameliorate experimental colitis.
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Academic Article
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Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells.
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Academic Article
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Diethylstilbestrol (DES) induces autophagy in thymocytes by regulating Beclin-1 expression through epigenetic modulation.
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Academic Article
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Resveratrol Attenuates Allergic Asthma and Associated Inflammation in the Lungs Through Regulation of miRNA-34a That Targets FoxP3 in Mice.
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Academic Article
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Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity.
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Academic Article
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MicroRNA-92 Expression in CD133+ Melanoma Stem Cells Regulates Immunosuppression in the Tumor Microenvironment via Integrin-Dependent Activation of TGF?.
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Academic Article
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Computational prediction and in vitro validation of VEGFR1 as a novel protein target for 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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Academic Article
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Murine lymphocytes exhibit heterogeneity in their proliferative responsiveness to calcium ionophore.
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Academic Article
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Characterization of T lymphocyte clones isolated from BCNU-cured LSA mice.
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Academic Article
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CD4-CD8- thymocytes from MRL-lpr/lpr mice exhibit abnormal proportions of alpha beta- and gamma delta-TCR+ cells and demonstrate defective responsiveness when activated through the TCR.
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Academic Article
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T-cell-receptor-independent activation of cytolytic activity of cytotoxic T lymphocytes mediated through CD44 and gp90MEL-14.
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Academic Article
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Role of IL-2, IL-4 and IL-6 in the growth and differentiation of tumor-specific CD4+ T helper and CD8+ T cytotoxic cells.
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Academic Article
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Characterization of tumor-infiltrating CD4+ T cells as Th1 cells based on lymphokine secretion and functional properties.
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Academic Article
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Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases.
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Academic Article
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Evidence for the existence of distinct heterogeneity among the peripheral CD4-CD8- T cells from MRL-lpr/lpr mice based on the expression of the J11d marker, activation requirements, and functional properties.
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Academic Article
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Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells.
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Academic Article
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Immunomodulatory effects of nitrosoureas on the phenotype and functions of T cells in the thymus and periphery.
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Academic Article
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Immunosuppression by aldicarb of T cell responses to antigen-specific and polyclonal stimuli results from defective IL-1 production by the macrophages.
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Academic Article
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Macrophages but not B cells from aged mice are defective in stimulating autoreactive T cells in vitro.
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Academic Article
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Immunomodulation by various nitrosoureas and its effect on the survival of the murine host bearing a syngeneic tumor.
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Academic Article
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Tumor-induced alteration in macrophage accessory cell activity on autoreactive T cells.
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Academic Article
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Calcium ionophores at concentrations mitogenic to normal murine T cells inhibit the proliferation of tumor cells in vitro.
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Academic Article
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Aldicarb suppresses macrophage but not natural killer (NK) cell-mediated cytotoxicity of tumor cells.
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Academic Article
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Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice.
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Academic Article
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Characterization of an endogenous Lyt2+ T-suppressor-cell population regulating autoreactive T cells in vitro and in vivo.
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Academic Article
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The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor.
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Academic Article
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Differential effects of BCNU on T cell, macrophage, natural killer and lymphokine-activated killer cell activities in mice bearing a syngeneic tumor.
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Academic Article
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Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells.
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Academic Article
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Impaired autoreactive T cell-induced T cell-T cell interaction in aged mice.
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Academic Article
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Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network.
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Academic Article
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Effect of experimental dengue virus infection on immune response of the host. I. Nature of changes in T suppressor cell activity regulating the B and T cell responses to heterologous antigens.
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Academic Article
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Immunotoxicity of AZT: inhibitory effect on thymocyte differentiation and peripheral T cell responsiveness to gp120 of human immunodeficiency virus.
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Academic Article
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Constitutive activation of the interleukin 2 gene in the induction of spontaneous in vitro transformation and tumorigenicity of T cells.
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Academic Article
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Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene.
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Academic Article
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Immunomodulatory properties of AZT.
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Academic Article
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Effect of radon on the immune system: alterations in the cellularity and functions of T cells in lymphoid organs of mouse.
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Academic Article
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Role of Fas apoptosis and MHC genes in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity of T cells.
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Academic Article
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Evidence for the participation of interleukin-2 (IL-2) and IL-4 in the regulation of autonomous growth and tumorigenesis of transformed cells of lymphoid origin.
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Academic Article
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Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo.
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Academic Article
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Hyaluronate-CD44 interactions can induce murine B-cell activation.
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Academic Article
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Fas-Fas ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: a lethal two-way street.
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Academic Article
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Characterization of phenotypic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocytes in vivo and its effect on apoptosis.
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Academic Article
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Role of CD44 in CTL and NK cell activity.
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Academic Article
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Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome.
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Academic Article
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Differential induction of apoptosis in activated and resting T cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T cell responsiveness.
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Academic Article
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Role of spontaneous and interleukin-2-induced natural killer cell activity in the cytotoxicity and rejection of Fas+ and Fas- tumor cells.
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Academic Article
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Role of environmental pollutants on immune functions, parasitic infections and limb malformations in marine toads and whistling frogs from Bermuda.
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Academic Article
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Targeted deletion of CD44v7 exon leads to decreased endothelial cell injury but not tumor cell killing mediated by interleukin-2-activated cytolytic lymphocytes.
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Academic Article
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Combined deficiency in CD44 and Fas leads to exacerbation of lymphoproliferative and autoimmune disease.
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Academic Article
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Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver.
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Academic Article
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Role of CD44 and hyaluronic acid (HA) in activation of alloreactive and antigen-specific T cells by bone marrow-derived dendritic cells.
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Academic Article
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Evidence for induction of apoptosis in T cells from murine fetal thymus following perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
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Academic Article
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Combined screening of thymocytes using apoptosis-specific cDNA array and promoter analysis yields novel gene targets mediating TCDD-induced toxicity.
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Academic Article
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Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on maternal immune response during pregnancy.
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Academic Article
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Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation.
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Academic Article
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2,3,7,8-tetrachlorodibenzo-p-dioxin enhances negative selection of T cells in the thymus but allows autoreactive T cells to escape deletion and migrate to the periphery.
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Academic Article
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Role of CD44 and its v7 isoform in staphylococcal enterotoxin B-induced toxic shock: CD44 deficiency on hepatic mononuclear cells leads to reduced activation-induced apoptosis that results in increased liver damage.
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Academic Article
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Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response.
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Academic Article
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Aryl hydrocarbon receptor-dependent induction of loss of mitochondrial membrane potential in epididydimal spermatozoa by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
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Academic Article
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Diethylstilbestrol alters positive and negative selection of T cells in the thymus and modulates T-cell repertoire in the periphery.
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Academic Article
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Superantigen-primed T cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) replicate poorly following recall encounter.
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Academic Article
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Mouse B cell activation is inhibited by CD44 cross-linking.
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Academic Article
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Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol.
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Academic Article
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Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
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Academic Article
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Role of CD4(+)CD25(+) T regulatory cells in IL-2-induced vascular leak.
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Academic Article
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CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: potential role for CB2-selective ligands as immunosuppressive agents.
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Academic Article
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Blockade of hyaluronan inhibits IL-2-induced vascular leak syndrome and maintains effectiveness of IL-2 treatment for metastatic melanoma.
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Academic Article
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Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation.
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Academic Article
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Endocannabinoids and immune regulation.
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Academic Article
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Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression.
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Academic Article
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American ginseng preferentially suppresses STAT/iNOS signaling in activated macrophages.
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Academic Article
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Role of CD44 in the differentiation of Th1 and Th2 cells: CD44-deficiency enhances the development of Th2 effectors in response to sheep RBC and chicken ovalbumin.
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Academic Article
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Evaluation of apoptosis in immunotoxicity testing.
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Academic Article
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Resveratrol suppresses colitis and colon cancer associated with colitis.
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Academic Article
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Immune modulation by chondroitin sulfate and its degraded disaccharide product in the development of an experimental model of multiple sclerosis.
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Academic Article
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An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes.
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Academic Article
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Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis.
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Academic Article
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CD44 Reciprocally regulates the differentiation of encephalitogenic Th1/Th17 and Th2/regulatory T cells through epigenetic modulation involving DNA methylation of cytokine gene promoters, thereby controlling the development of experimental autoimmune encephalomyelitis.
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Academic Article
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CD1d-independent activation of invariant natural killer T cells by staphylococcal enterotoxin B through major histocompatibility complex class II/T cell receptor interaction results in acute lung injury.
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Academic Article
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Robust antimicrobial compounds and polymers derived from natural resin acids.
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Academic Article
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A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms.
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Academic Article
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Acute lung injury induced by Staphylococcal enterotoxin B: disruption of terminal vessels as a mechanism of induction of vascular leak.
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Academic Article
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Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury.
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Academic Article
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A limited role of p53 on the ability of a Hexane fraction of American ginseng to suppress mouse colitis.
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Academic Article
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Role of interleukin-10 in the regulation of tumorigenicity of a T cell lymphoma.
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Academic Article
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The role of IL-2 in the activation and expansion of regulatory T-cells and the development of experimental autoimmune encephalomyelitis.
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Academic Article
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American ginseng inhibits vascular smooth muscle cell proliferation via suppressing Jak/Stat pathway.
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Academic Article
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Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.
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Academic Article
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Role of cytokines as a double-edged sword in sepsis.
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Academic Article
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Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction.
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Academic Article
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Staphylococcal enterotoxin B-induced microRNA-155 targets SOCS1 to promote acute inflammatory lung injury.
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Academic Article
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Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice.
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Academic Article
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3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways.
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Academic Article
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Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease.
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Academic Article
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?(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells.
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Academic Article
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Dose-dependent benefits of quercetin on tumorigenesis in the C3(1)/SV40Tag transgenic mouse model of breast cancer.
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Academic Article
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Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.
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Academic Article
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3,3'-Diindolylmethane attenuates LPS-mediated acute liver failure by regulating miRNAs to target IRAK4 and suppress Toll-like receptor signalling.
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Academic Article
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Role of miRNA in the regulation of inflammatory genes in staphylococcal enterotoxin B-induced acute inflammatory lung injury and mortality.
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Academic Article
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Kruppel-like factor KLF4 facilitates cutaneous wound healing by promoting fibrocyte generation from myeloid-derived suppressor cells.
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Academic Article
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Epigenetic Regulation of Immunological Alterations Following Prenatal Exposure to Marijuana Cannabinoids and its Long Term Consequences in Offspring.
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Academic Article
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Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages.
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Academic Article
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Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis.
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Academic Article
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Natural indoles, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis.
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Academic Article
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?9-Tetrahydrocannabinol-mediated epigenetic modifications elicit myeloid-derived suppressor cell activation via STAT3/S100A8.
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Academic Article
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Protective role of cannabinoid receptor 2 activation in galactosamine/lipopolysaccharide-induced acute liver failure through regulation of macrophage polarization and microRNAs.
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Academic Article
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Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy.
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Academic Article
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NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment.
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Academic Article
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??-Tetrahydrocannabinol attenuates allogeneic host-versus-graft response and delays skin graft rejection through activation of cannabinoid receptor 1 and induction of myeloid-derived suppressor cells.
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Academic Article
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Purinergic receptor X7 mediates leptin induced GLUT4 function in stellate cells in nonalcoholic steatohepatitis.
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Academic Article
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A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes.
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Academic Article
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Nrf2-Mediated Cardiac Maladaptive Remodeling and Dysfunction in a Setting of Autophagy Insufficiency.
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Academic Article
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Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain.
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Academic Article
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Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.
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Academic Article
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MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer.
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Academic Article
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3,39-Diindolylmethane Ameliorates Staphylococcal Enterotoxin B?Induced Acute Lung Injury through Alterations in the Expression of MicroRNA that Target Apoptosis and Cell-Cycle Arrest in Activated T Cells.
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Academic Article
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High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer.
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Academic Article
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Marijuana-derived ?-9-tetrahydrocannabinol suppresses Th1/Th17 cell-mediated delayed-type hypersensitivity through microRNA regulation.
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Academic Article
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Production of endocannabinoids by activated T?cells and B?cells modulates inflammation associated with delayed-type hypersensitivity.
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Academic Article
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MicroRNAs associated with the pathogenesis of multiple sclerosis.
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Academic Article
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RNA-seq Analysis of d9-Tetrahydrocannabinol-treated T Cells Reveals Altered Gene Expression Profiles That Regulate Immune Response and Cell Proliferation.
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Academic Article
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Repurposing the anti-malarial drug, quinacrine: new anti-colitis properties.
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Academic Article
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Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model.
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Academic Article
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TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.
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Academic Article
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A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice.
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Academic Article
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Looking for the best anti-colitis medicine: A comparative analysis of current and prospective compounds.
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Academic Article
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Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple negative breast cancer model.
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Academic Article
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Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma.
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Academic Article
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Trio Act of Boronolectin with Antibiotic-Metal Complexed Macromolecules toward Broad-Spectrum Antimicrobial Efficacy.
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Academic Article
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Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer.
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Academic Article
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Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity.
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Academic Article
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Charged Metallopolymer-Grafted Silica Nanoparticles for Antimicrobial Applications.
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Academic Article
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The role of gut microbiome and associated metabolome in the regulation of neuroinflammation in multiple sclerosis and its implications in attenuating chronic inflammation in other inflammatory and autoimmune disorders.
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Academic Article
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Resveratrol protects mice against SEB-induced acute lung injury and mortality by miR-193a modulation that targets TGF-? signalling.
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Academic Article
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High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease.
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Academic Article
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miR-466a Targeting of TGF-?2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation.
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Academic Article
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Evaluation of Cell Proliferation and Apoptosis in Immunotoxicity Testing.
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Academic Article
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MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages.
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Academic Article
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Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent.
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Academic Article
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Role of MicroRNAs Induced by Chinese Herbal Medicines Against Hepatocellular Carcinoma: A Brief Review.
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Academic Article
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Effects of high fat diet-induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model.
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Academic Article
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Comparative analysis of interactions between aryl hydrocarbon receptor ligand binding domain with its ligands: a computational study.
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Academic Article
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Impact of 5 fluorouracil chemotherapy on gut inflammation, functional parameters, and gut microbiota.
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Academic Article
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Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells.
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Academic Article
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Resveratrol (3, 5, 4'-Trihydroxy-trans-Stilbene) Attenuates a Mouse Model of Multiple Sclerosis by Altering the miR-124/Sphingosine Kinase 1 Axis in Encephalitogenic T Cells in the Brain.
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The role of gut microbiota in shaping the relapse-remitting and chronic-progressive forms of multiple sclerosis in mouse models.
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Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells.
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Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease.
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Acute and short-term administrations of delta-9-tetrahydrocannabinol modulate major gut metabolomic regulatory pathways in C57BL/6 mice.
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Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome.
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Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.
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Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation.
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AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes.
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Combination of Cannabinoids, ?9- Tetrahydrocannabinol and Cannabidiol, Ameliorates Experimental Multiple Sclerosis by Suppressing Neuroinflammation Through Regulation of miRNA-Mediated Signaling Pathways.
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Cannabidiol Regulates Gene Expression in Encephalitogenic T cells Using Histone Methylation and noncoding RNA during Experimental Autoimmune Encephalomyelitis.
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Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis.
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Resveratrol Downregulates miR-31 to Promote T Regulatory Cells during Prevention of TNBS-Induced Colitis.
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Facial Amphiphilicity-Induced Polymer Nanostructures for Antimicrobial Applications.
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Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
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Evidence for the involvement of CD44 in endothelial cell injury and induction of vascular leak syndrome by IL-2.
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Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity.
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Growth of FasL-bearing tumor cells in syngeneic murine host induces apoptosis and toxicity in Fas(+) organs.
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CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death.
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Evidence for estradiol-induced apoptosis and dysregulated T cell maturation in the thymus.
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Enhanced activation-induced cell death as a mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immunotoxicity in peripheral T cells.
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Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
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Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo.
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Analysis of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced gene expression profile in vivo using pathway-specific cDNA arrays.
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Cannabinoid Receptor Activation on Haematopoietic Cells and Enterocytes Protects against Colitis.
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Extracts of select endemic plants from the Republic of Mauritius exhibiting anti-cancer and immunomodulatory properties.
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Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance.
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Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation.
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Autophagy Inhibition Enables Nrf2 to Exaggerate the Progression of Diabetic Cardiomyopathy in Mice.
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From Suppressor T cells to Regulatory T cells: How the Journey That Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation.
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AhR Activation Leads to Alterations in the Gut Microbiome with Consequent Effect on Induction of Myeloid Derived Suppressor Cells in a CXCR2-Dependent Manner.
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Safety of natural anthraquinone emodin: an assessment in mice.
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AhR Ligands Differentially Regulate miRNA-132 Which Targets HMGB1 and to Control the Differentiation of Tregs and Th-17 Cells During Delayed-Type Hypersensitivity Response.
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Resveratrol-mediated attenuation of superantigen-driven acute respiratory distress syndrome is mediated by microbiota in the lungs and gut.
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Regulation of Intestinal Stem Cell Stemness by the Aryl Hydrocarbon Receptor and Its Ligands.
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Mature Vascular Smooth Muscle Cells, but Not Endothelial Cells, Serve as the Major Cellular Source of Intimal Hyperplasia in Vein Grafts.
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Apigenin Modulates Dendritic Cell Activities and Curbs Inflammation Via RelB Inhibition in the Context of Neuroinflammatory Diseases.
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CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes.
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Molecules from American Ginseng Suppress Colitis through Nuclear Factor Erythroid-2-Related Factor 2.
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Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis.
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Protective effects of ?9 -tetrahydrocannabinol against enterotoxin-induced acute respiratory distress syndrome are mediated by modulation of microbiota.
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Higher intestinal and circulatory lactate associated NOX2 activation leads to an ectopic fibrotic pathology following microcystin co-exposure in murine fatty liver disease.
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?9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression.
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Immune and microRNA responses to Helicobacter muridarum infection and indole-3-carbinol during colitis.
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The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota.
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Epigenetic Regulation of Cannabinoid-Mediated Attenuation of Inflammation and Its Impact on the Use of Cannabinoids to Treat Autoimmune Diseases.
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Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
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Skin Mast Cell-Driven Ceramides Drive Early Apoptosis in Pre-Symptomatic Eczema in Mice.
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Biodegradable polycaprolactone metallopolymer-antibiotic bioconjugates containing phenylboronic acid and cobaltocenium for antimicrobial application.
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Effects of Acute 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Exposure on the Circulating and Cecal Metabolome Profile.
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Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome through Modulation of Microbiome in the Gut-Lung Axis.
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Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel.
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Identification and Biosynthesis of Pro-Inflammatory Sulfonolipids from an Opportunistic Pathogen Chryseobacterium gleum.
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Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases.
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Emodin reduces tumor burden by diminishing M2-like macrophages in colorectal cancer.
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The Ability of Resveratrol to Attenuate Ovalbumin-Mediated Allergic Asthma Is Associated With Changes in Microbiota Involving the Gut-Lung Axis, Enhanced Barrier Function and Decreased Inflammation in the Lungs.
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AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver.
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Production of MHCII-expressing classical monocytes increases during aging in mice and humans.
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Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice.
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