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Spinale, Francis
One or more keywords matched the following items that are connected to Spinale, Francis
Item TypeName
Academic Article Large animal models of congestive heart failure: a critical step in translating basic observations into clinical applications.
Academic Article Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling.
Academic Article Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor.
Academic Article Modulation of calcium transport improves myocardial contractility and enzyme profiles after prolonged ischemia-reperfusion.
Academic Article Myocyte contractility with caspase inhibition and simulated hyperkalemic cardioplegic arrest.
Academic Article Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms.
Academic Article Trafficking of the membrane type-1 matrix metalloproteinase in ischemia and reperfusion: relation to interstitial membrane type-1 matrix metalloproteinase activity.
Academic Article Age-dependent changes in myocardial matrix metalloproteinase/tissue inhibitor of metalloproteinase profiles and fibroblast function.
Academic Article Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling.
Academic Article Pathways of matrix metalloproteinase induction in heart failure: bioactive molecules and transcriptional regulation.
Academic Article Selective targeting of matrix metalloproteinase inhibition in post-infarction myocardial remodeling.
Academic Article Matrix metalloproteinase-7 affects connexin-43 levels, electrical conduction, and survival after myocardial infarction.
Academic Article Protein kinase C isoform activation and endothelin-1 mediated defects in myocyte contractility after cardioplegic arrest and reperfusion.
Academic Article Differential effects of protein kinase C isoform activation in endothelin-mediated myocyte contractile dysfunction with cardioplegic arrest and reperfusion.
Academic Article Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation.
Academic Article Proteinase systems and thoracic aortic aneurysm progression.
Academic Article Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function.
Academic Article Altered transforming growth factor-beta signaling in a murine model of thoracic aortic aneurysm.
Academic Article Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion.
Academic Article Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I.
Academic Article Aprotinin modifies left ventricular contractility and cytokine release after ischemia-reperfusion in a dose-dependent manner in a murine model.
Academic Article Differential effect of wall tension on matrix metalloproteinase promoter activation in the thoracic aorta.
Academic Article Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling.
Academic Article Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction.
Academic Article Large animal models of heart failure: a critical link in the translation of basic science to clinical practice.
Academic Article Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
Academic Article Pathophysiology of myocardial injury and remodeling: implications for molecular imaging.
Academic Article Long-term localized high-frequency electric stimulation within the myocardial infarct: effects on matrix metalloproteinases and regional remodeling.
Academic Article Cardiac function and circulating cytokines after endotoxin exposure in neonatal mice.
Academic Article Amplified bioactive signaling and proteolytic enzymes following ischemia reperfusion and aging: remodeling pathways that are not like a fine wine.
Academic Article Heterogeneity in MT1-MMP activity with ischemia-reperfusion and previous myocardial infarction: relation to regional myocardial function.
Academic Article Myocardial remodeling: cellular and extracellular events and targets.
Academic Article TNF-alpha and myocardial matrix metalloproteinases in heart failure: relationship to LV remodeling.
Academic Article Matrix metalloproteinases: regulation and dysregulation in the failing heart.
Academic Article Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective.
Academic Article Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment.
Academic Article Cardiorenal effects of adenosine subtype 1 (A1) receptor inhibition in an experimental model of heart failure.
Academic Article Continuous localized monitoring of plasmin activity identifies differential and regional effects of the serine protease inhibitor aprotinin: relevance to antifibrinolytic therapy.
Academic Article Myocardial remodeling with aortic stenosis and after aortic valve replacement: mechanisms and future prognostic implications.
Academic Article Targeted regional injection of biocomposite microspheres alters post-myocardial infarction remodeling and matrix proteolytic pathways.
Academic Article Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature.
Academic Article Diversity of myocardial interstitial proteolytic pathways: gene deletion reveals unexpected consequences.
Academic Article Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: relationship to interstitial microRNA dynamics and myocardial function.
Academic Article Membrane-associated matrix proteolysis and heart failure.
Academic Article Gender differences in non-ischemic myocardial remodeling: are they due to estrogen modulation of cardiac mast cells and/or membrane type 1 matrix metalloproteinase.
Academic Article Bioactive peptide signaling within the myocardial interstitium and the matrix metalloproteinases.
Academic Article Changes in extracellular collagen matrix alter myocardial systolic performance.
Academic Article Extracellular degradative pathways in myocardial remodeling and progression to heart failure.
Academic Article The extracellular matrix: summation.
Academic Article Myocardial infarct expansion and matrix metalloproteinase inhibition.
Academic Article Selective matrix metalloproteinase inhibition with developing heart failure: effects on left ventricular function and structure.
Academic Article Matrix metalloproteinase inhibition modifies left ventricular remodeling after myocardial infarction in pigs.
Academic Article Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling.
Academic Article A murine model of thoracic aortic aneurysms.
Academic Article Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion.
Academic Article Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway.
Academic Article Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes.
Academic Article Cell-matrix signaling and thrombospondin: another link to myocardial matrix remodeling.
Academic Article Duality of innate stress responses in cardiac injury, repair, and remodeling.
Academic Article Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease.
Academic Article Caspase inhibition attenuates contractile dysfunction following cardioplegic arrest and rewarming in the setting of left ventricular failure.
Academic Article Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition.
Academic Article Myocardial interstitial matrix metalloproteinase activity is altered by mechanical changes in LV load: interaction with the angiotensin type 1 receptor.
Academic Article Matrix modulation and heart failure: new concepts question old beliefs.
Academic Article Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction.
Academic Article Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction.
Academic Article Effects of deletion of the matrix metalloproteinase 9 gene on development of murine thoracic aortic aneurysms.
Academic Article Infarct size reduction and attenuation of global left ventricular remodeling with the CorCap cardiac support device following acute myocardial infarction in sheep.
Academic Article From tadpole tails to transgenic mice: metalloproteinases have brought about a metamorphosis in our understanding of cardiovascular disease.
Academic Article Alterations in cultured myocardial fibroblast function following the development of left ventricular failure.
Academic Article Chronic matrix metalloproteinase inhibition following myocardial infarction in mice: differential effects on short and long-term survival.
Academic Article Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction.
Academic Article Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion.
Academic Article Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation.
Academic Article Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice.
Academic Article Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis.
Academic Article Targeted myocardial microinjections of a biocomposite material reduces infarct expansion in pigs.
Academic Article Calpain inhibition preserves myocardial structure and function following myocardial infarction.
Academic Article Differential effects of mechanical and biological stimuli on matrix metalloproteinase promoter activation in the thoracic aorta.
Academic Article Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging.
Academic Article Caspase inhibition modulates left ventricular remodeling following myocardial infarction through cellular and extracellular mechanisms.
Academic Article Temporally and regionally disparate differences in plasmin activity by tranexamic acid.
Academic Article Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart.
Academic Article Interstitial plasmin activity with epsilon aminocaproic acid: temporal and regional heterogeneity.
Academic Article Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model.
Academic Article Short-term disruption in regional left ventricular electrical conduction patterns increases interstitial matrix metalloproteinase activity.
Academic Article Spatiotemporal induction of matrix metalloproteinase-9 transcription after discrete myocardial injury.
Academic Article Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction.
Academic Article Discordant activation of gene promoters for matrix metalloproteinases and tissue inhibitors of the metalloproteinases following myocardial infarction.
Academic Article Hemodynamics and myocardial blood flow patterns after placement of a cardiac passive restraint device in a model of dilated cardiomyopathy.
Academic Article Targeted imaging of the spatial and temporal variation of matrix metalloproteinase activity in a porcine model of postinfarct remodeling: relationship to myocardial dysfunction.
Academic Article Direct regulation of membrane type 1 matrix metalloproteinase following myocardial infarction causes changes in survival, cardiac function, and remodeling.
Academic Article Changes in the myocardial interstitium and contribution to the progression of heart failure.
Academic Article Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis.
Academic Article Animal models of heart failure: a scientific statement from the American Heart Association.
Academic Article Gene targeting in ischemic heart disease and failure: translational and clinical studies.
Academic Article Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression.
Academic Article Epilysin (matrix metalloproteinase-28) joins the matrix metalloproteinase team on the field of postmyocardial infarction remodeling.
Academic Article Biomarkers and heart disease: what is translational success?
Academic Article Integrating the myocardial matrix into heart failure recognition and management.
Concept Disease Models, Animal
Concept Animals, Newborn
Concept Animals
Concept Models, Animal
Academic Article Pulmonary artery endothelial cell phenotypic alterations in a large animal model of pulmonary arteriovenous malformations after the Glenn shunt.
Academic Article Reproducible porcine model of thoracic aortic aneurysm.
Academic Article Cyclosporin A in left ventricular remodeling after myocardial infarction.
Academic Article Mechanistic relationship between membrane type-1 matrix metalloproteinase and the myocardial response to pressure overload.
Academic Article Local hydrogel release of recombinant TIMP-3 attenuates adverse left ventricular remodeling after experimental myocardial infarction.
Academic Article Targeted overexpression of tissue inhibitor of matrix metalloproteinase-4 modifies post-myocardial infarction remodeling in mice.
Academic Article Myocardial fibroblast-matrix interactions and potential therapeutic targets.
Academic Article Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition.
Academic Article Targeting matrix metalloproteinases in heart disease: lessons from endogenous inhibitors.
Academic Article Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy.
Academic Article Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction.
Academic Article Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice.
Academic Article Regional and temporal changes in left ventricular strain and stiffness in a porcine model of myocardial infarction.
Academic Article Assessment of Cardiac Function--Basic Principles and Approaches.
Academic Article Sonomicrometry-Based Analysis of Post-Myocardial Infarction Regional Mechanics.
Academic Article Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research.
Academic Article In vivo assessment of regional mechanics post-myocardial infarction: A focus on the road ahead.
Academic Article Intracoronary delivery of recombinant TIMP-3 after myocardial infarction: effects on myocardial remodeling and function.
Academic Article Institution of localized high-frequency electrical stimulation targeting early myocardial infarction: Effects on left ventricle function and geometry.
Academic Article Delivery of a matrix metalloproteinase-responsive hydrogel releasing TIMP-3 after myocardial infarction: effects on left ventricular remodeling.
Academic Article Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype.
Academic Article Speckle-Tracking Echocardiography Enables Model-Based Identification of Regional Stiffness Indices in the Left Ventricular Myocardium.
Academic Article The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart.
Academic Article Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic 201Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling.
Academic Article Ubiquitin ligase Wwp1 gene deletion attenuates diastolic dysfunction in pressure-overload hypertrophy.
Academic Article Regional heterogeneity in determinants of atrial matrix remodeling and association with atrial fibrillation vulnerability postmyocardial infarction.
Academic Article Matrix Metalloproteinase-Targeted SPECT/CT Imaging for Evaluation of Therapeutic Hydrogels for the Early Modulation of Post-Infarct Myocardial Remodeling.
Academic Article Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum.
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