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One or more keywords matched the following properties of Carroll, Steven
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keywords genetically engineered mouse models
One or more keywords matched the following items that are connected to Carroll, Steven
Item TypeName
Concept Mice, Knockout
Concept Mice
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Concept Mice, Inbred NOD
Concept Mice, Nude
Concept Mice, SCID
Concept Mice, Neurologic Mutants
Academic Article Elements in the 5' flanking sequences of the mouse low-affinity NGF receptor gene direct appropriate CNS, but not PNS, expression in transgenic mice.
Academic Article Expression of JE (monocyte chemoattractant protein-1) is induced by sciatic axotomy in wild type rodents but not in C57BL/Wld(s) mice.
Academic Article Attenuation of experimental autoimmune demyelination in complement-deficient mice.
Academic Article Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease.
Academic Article Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.
Academic Article BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.
Academic Article Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.
Academic Article Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.
Academic Article Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease.
Academic Article Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.
Academic Article Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents.
Academic Article Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
Academic Article Parsing out reality from genetically engineered mouse models of neurologic diseases.
Academic Article Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis.
Academic Article Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.
Academic Article Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.
Academic Article Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines.
Academic Article Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.
Academic Article The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.
Academic Article STAT1 and NF-?B Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells.
Academic Article Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.
Academic Article Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors.
Academic Article ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.
Award or Honor Receipt Guest Editor, "Genetically Engineered Mouse Models of Neurologic Diseases"
Grant Evaluating the role of NRG-1 receptors in MPNST tumorigenesis
Grant Novel Treatment of NF-1 Associated Malignant Peripheral Nerve Sheath Tumors
Grant Regulation of Ras isoforms in malignant peripheral nerve sheath tumors
Grant Multi-Modal Lysosomotropic Death Therapy for Malignant Peripheral Nerve Sheath Tu
Grant Role of Neuregulin-1 in Schwann Cell Neoplasia
Academic Article A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
Academic Article Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal.
Academic Article Developmental, neurochemical, and behavioral analyses of ErbB4 Cyt-1 knockout mice.
Academic Article Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease.
Academic Article Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells.
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