| Item Type | Name |
|
Concept
|
Optic Nerve Neoplasms
|
|
Concept
|
Receptors, Nerve Growth Factor
|
|
Concept
|
Sciatic Nerve
|
|
Concept
|
Nerve Fibers, Unmyelinated
|
|
Concept
|
Spinal Nerve Roots
|
|
Concept
|
Nerve Degeneration
|
|
Concept
|
Nerve Sheath Neoplasms
|
|
Concept
|
Nerve Fibers, Myelinated
|
|
Concept
|
Nerve Growth Factor
|
|
Concept
|
Nerve Growth Factors
|
|
Concept
|
Receptor, Nerve Growth Factor
|
|
Concept
|
Nerve Tissue Proteins
|
|
Academic Article
|
Elements in the 5' flanking sequences of the mouse low-affinity NGF receptor gene direct appropriate CNS, but not PNS, expression in transgenic mice.
|
|
Academic Article
|
Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia.
|
|
Academic Article
|
Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration.
|
|
Academic Article
|
Neurotrophin sensitivity of prevertebral and paravertebral rat sympathetic autonomic ganglia.
|
|
Academic Article
|
Expression of JE (monocyte chemoattractant protein-1) is induced by sciatic axotomy in wild type rodents but not in C57BL/Wld(s) mice.
|
|
Academic Article
|
Lysophosphatidic acid promotes the proliferation of adult Schwann cells isolated from axotomized sciatic nerve.
|
|
Academic Article
|
Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line.
|
|
Academic Article
|
Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.
|
|
Academic Article
|
Constitutive activation of the neuregulin-1/erbB signaling pathway promotes the proliferation of a human peripheral neuroepithelioma cell line.
|
|
Academic Article
|
ErbB transmembrane tyrosine kinase receptors are expressed by sensory and motor neurons projecting into sciatic nerve.
|
|
Academic Article
|
Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons.
|
|
Academic Article
|
Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors. I. The role of tumor suppressor mutations.
|
|
Academic Article
|
Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling.
|
|
Academic Article
|
Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.
|
|
Academic Article
|
Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis.
|
|
Academic Article
|
Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis.
|
|
Academic Article
|
Differential activation of c-fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.
|
|
Academic Article
|
Neuregulin-1 beta and neuregulin-1 alpha differentially affect the migration and invasion of malignant peripheral nerve sheath tumor cells.
|
|
Academic Article
|
Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.
|
|
Academic Article
|
Orthotopic xenografting of human luciferase-tagged malignant peripheral nerve sheath tumor cells for in vivo testing of candidate therapeutic agents.
|
|
Academic Article
|
Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
|
|
Academic Article
|
Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms.
|
|
Academic Article
|
The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
|
|
Academic Article
|
Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis.
|
|
Academic Article
|
Malignant peripheral nerve sheath tumor invasion requires aberrantly expressed EGF receptors and is variably enhanced by multiple EGF family ligands.
|
|
Academic Article
|
4-Hydroxytamoxifen induces autophagic death through K-Ras degradation.
|
|
Academic Article
|
Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.
|
|
Academic Article
|
BNIP3 regulates AT101 [(-)-gossypol] induced death in malignant peripheral nerve sheath tumor cells.
|
|
Academic Article
|
Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.
|
|
Academic Article
|
Assessment of oncolytic HSV efficacy following increased entry-receptor expression in malignant peripheral nerve sheath tumor cell lines.
|
|
Academic Article
|
Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.
|
|
Academic Article
|
Correction: BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells.
|
|
Academic Article
|
The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.
|
|
Academic Article
|
STAT1 and NF-?B Inhibitors Diminish Basal Interferon-Stimulated Gene Expression and Improve the Productive Infection of Oncolytic HSV in MPNST Cells.
|
|
Academic Article
|
BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells.
|
|
Academic Article
|
The Molecular and Morphologic Structures That Make Saltatory Conduction Possible in Peripheral Nerve.
|
|
Academic Article
|
Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero.
|
|
Academic Article
|
The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally.
|
|
Academic Article
|
Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors.
|
|
Academic Article
|
The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.
|
|
Academic Article
|
ErbB4 promotes malignant peripheral nerve sheath tumor pathogenesis via Ras-independent mechanisms.
|
|
Grant
|
NEUREGULINS AND THE PATHOLOGY OF NERVE INJURY
|
|
Grant
|
Prevention and Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors
|
|
Grant
|
Evaluating the role of NRG-1 receptors in MPNST tumorigenesis
|
|
Grant
|
Novel Treatment of NF-1 Associated Malignant Peripheral Nerve Sheath Tumors
|
|
Grant
|
Evaluation of the Effectiveness of Calmodulin Inhibitors for the Treatment of Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors
|
|
Grant
|
Malignant Peripheral Nerve Sheath Tumors' Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling
|
|
Grant
|
Engineered Herpes Siumplex Viruses for the Treatment of Malignant Peripheral Nerve Sheath Tumors
|
|
Grant
|
Regulation of Ras isoforms in malignant peripheral nerve sheath tumors
|
|
Grant
|
Multi-Modal Lysosomotropic Death Therapy for Malignant Peripheral Nerve Sheath Tu
|
|
Grant
|
The Role of HER3 and IGF1R, through Non-Classical Ras Signaling, on Malignant Peripheral Nerve Sheath Tumor Progression
|
|
Grant
|
Comparative Oncogenomics for Peripheral Nerve Sheath Cancer Gene Discovery
|
|
Grant
|
Role of Neuregulin-1 in Schwann Cell Neoplasia
|
|
Academic Article
|
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
|
|
Academic Article
|
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
|
|
Academic Article
|
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.
|
|
Academic Article
|
Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells.
|
|
Academic Article
|
LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells.
|