Antonios Kourtidis

Title
InstitutionMedical University of South Carolina
DepartmentRegenerative Medicine and Cell Biology
AddressP.O. Box MSC 508
BSB 650
Basic Science Building - 173 Ashley Ave.
Phone843-792-9170
Fax843-792-0664
ORCID ORCID Icon0000-0002-8128-6391 Additional info
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    Collapse Biography 
    Collapse education and training
    Aristotle University of Thessaloniki, GreecePhD12/2004Molecular Biology
    State University of New York, Albany, NYPostdoctoral Fellow06/2009Molecular Biology of Cancer
    Mayo Clinic Cancer Center, Jacksonville, FLInstructor07/2016Cell Biology of cancer

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Daulagala AC, Bridges MC, Kourtidis A. E-cadherin Beyond Structure: A Signaling Hub in Colon Homeostasis and Disease. Int J Mol Sci. 2019 Jun 05; 20(11). PMID: 31195621.
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    2. Rea K, Roggiani F, De Cecco L, Raspagliesi F, Carcangiu ML, Nair-Menon J, Bagnoli M, Bortolomai I, Mezzanzanica D, Canevari S, Kourtidis A, Anastasiadis PZ, Tomassetti A. Simultaneous E-cadherin and PLEKHA7 expression negatively affects E-cadherin/EGFR mediated ovarian cancer cell growth. J Exp Clin Cancer Res. 2018 Jul 11; 37(1):146. PMID: 29996940.
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    3. Kourtidis A, Anastasiadis PZ. Close encounters of the RNAi kind: the silencing life of the adherens junctions. Curr Opin Cell Biol. 2018 10; 54:30-36. PMID: 29587176.
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    4. Kourtidis A, Necela B, Lin WH, Lu R, Feathers RW, Asmann YW, Thompson EA, Anastasiadis PZ. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017 10 02; 216(10):3073-3085. PMID: 28877994.
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    5. Kourtidis A, Lu R, Pence LJ, Anastasiadis PZ. A central role for cadherin signaling in cancer. Exp Cell Res. 2017 09 01; 358(1):78-85. PMID: 28412244.
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    6. Fiorotto R, Villani A, Kourtidis A, Scirpo R, Amenduni M, Geibel PJ, Cadamuro M, Spirli C, Anastasiadis PZ, Strazzabosco M. The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity. Hepatology. 2016 12; 64(6):2118-2134. PMID: 27629435.
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    7. Kourtidis A, Anastasiadis PZ. Bringing together cell-to-cell adhesion and miRNA biology in cancer research. Future Oncol. 2016 May; 12(10):1211-4. PMID: 26923006.
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    8. Kourtidis A, Anastasiadis PZ. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016; 15(4):498-505. PMID: 26822694.
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    9. Kourtidis A, Yanagisawa M, Huveldt D, Copland JA, Anastasiadis PZ. Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer. PLoS One. 2015; 10(6):e0129964. PMID: 26067913.
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    10. Xu D, Chatakonda VK, Kourtidis A, Conklin DS, Shi H. In search of novel drug target sites on estrogen receptors using RNA aptamers. Nucleic Acid Ther. 2014 Jun; 24(3):226-38. PMID: 24588102.
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    11. Dachsel JC, Ngok SP, Lewis-Tuffin LJ, Kourtidis A, Geyer R, Johnston L, Feathers R, Anastasiadis PZ. The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration. Mol Cell Biol. 2013 Dec; 33(24):4909-18. PMID: 24126053.
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    12. Eifert C, Wang X, Kokabee L, Kourtidis A, Jain R, Gerdes MJ, Conklin DS. A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis. Genes Chromosomes Cancer. 2013 Oct; 52(10):961-75. PMID: 23913792.
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    13. Ngok SP, Geyer R, Kourtidis A, Mitin N, Feathers R, Der C, Anastasiadis PZ. TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function. J Cell Sci. 2013 Aug 01; 126(Pt 15):3271-7. PMID: 23729734.
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    14. Ngok SP, Geyer R, Kourtidis A, Storz P, Anastasiadis PZ. Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx. J Biol Chem. 2013 Mar 01; 288(9):6640-50. PMID: 23335514.
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    15. Kourtidis A, Ngok SP, Anastasiadis PZ. p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression. Prog Mol Biol Transl Sci. 2013; 116:409-32. PMID: 23481205.
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    16. Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012 Dec 24; 199(7):1103-15. PMID: 23253477.
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    17. Kourtidis A, Jain R, Carkner RD, Eifert C, Brosnan MJ, Conklin DS. An RNA interference screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature. Cancer Res. 2010 Mar 01; 70(5):1783-92. PMID: 20160030.
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    18. Adam AP, George A, Schewe D, Bragado P, Iglesias BV, Ranganathan AC, Kourtidis A, Conklin DS, Aguirre-Ghiso JA. Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence. Cancer Res. 2009 Jul 15; 69(14):5664-72. PMID: 19584293.
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    19. Kourtidis A, Srinivasaiah R, Carkner RD, Brosnan MJ, Conklin DS. Peroxisome proliferator-activated receptor-gamma protects ERBB2-positive breast cancer cells from palmitate toxicity. Breast Cancer Res. 2009; 11(2):R16. PMID: 19298655.
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    20. Pantzartzi CN, Kourtidis A, Drosopoulou E, Yiangou M, Scouras ZG. Isolation and characterization of two cytoplasmic hsp90s from Mytilus galloprovincialis (Mollusca: Bivalvia) that contain a complex promoter with a p53 binding site. Gene. 2009 Feb 15; 431(1-2):47-54. PMID: 19061940.
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    21. O'Connell CB, Loncarek J, Hergert P, Kourtidis A, Conklin DS, Khodjakov A. The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes. J Cell Biol. 2008 Oct 06; 183(1):29-36. PMID: 18824563.
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    22. Ranganathan AC, Ojha S, Kourtidis A, Conklin DS, Aguirre-Ghiso JA. Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival. Cancer Res. 2008 May 01; 68(9):3260-8. PMID: 18451152.
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    23. Lastro M, Kourtidis A, Farley K, Conklin DS. xCT expression reduces the early cell cycle requirement for calcium signaling. Cell Signal. 2008 Feb; 20(2):390-9. PMID: 18054200.
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    24. Evans SC, Kourtidis A, Markham TS, Miller J, Conklin DS, Torres AS. MicroRNA target detection and analysis for genes related to breast cancer using MDLcompress. EURASIP J Bioinform Syst Biol. 2007; 43670. PMID: 18317504.
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    25. Kourtidis A, Eifert C, Conklin DS. RNAi applications in target validation. Ernst Schering Res Found Workshop. 2007; (61):1-21. PMID: 17249494.
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    26. Kourtidis A, Drosopoulou E, Pantzartzi CN, Chintiroglou CC, Scouras ZG. Three new satellite sequences and a mobile element found inside HSP70 introns of the Mediterranean mussel (Mytilus galloprovincialis). Genome. 2006 Nov; 49(11):1451-8. PMID: 17426760.
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    27. Kourtidis A, Drosopoulou E, Nikolaidis N, Hatzi VI, Chintiroglou CC, Scouras ZG. Identification of several cytoplasmic HSP70 genes from the Mediterranean mussel (Mytilus galloprovincialis) and their long-term evolution in Mollusca and Metazoa. J Mol Evol. 2006 Apr; 62(4):446-59. PMID: 16547643.
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    28. Kourtidis A, Scouras ZG. Analysis and characterization of the transcriptional unit of a new Mytilus galloprovincialis (Mollusca: Bivalvia) hsp70 gene. DNA Seq. 2005 Feb; 16(1):36-43. PMID: 16040345.
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    29. Orr RK, Hoehn JL, Col NF. The learning curve for sentinel node biopsy in breast cancer: practical considerations. Arch Surg. 1999 Jul; 134(7):764-7. PMID: 26302406.
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