Peroxynitrous Acid

"Peroxynitrous Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A potent oxidant synthesized by the cell during its normal metabolism. Peroxynitrite is formed from the reaction of two free radicals, NITRIC OXIDE and the superoxide anion (SUPEROXIDES).

Descriptor ID	D030421
MeSH Number(s)	D01.625.600.800 D01.625.700.750
Concept/Terms	Peroxynitrous Acid Peroxynitrous Acid Acid, Peroxynitrous Acids, Peroxynitrous Peroxynitrous Acids Peroxynitrous Acid, Potassium Salt Peroxynitrous Acid, Potassium Salt Peroxynitrite Peroxynitrite Peroxynitrites Peroxonitrite Peroxonitrites

Below are MeSH descriptors whose meaning is more general than "Peroxynitrous Acid".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Nitrogen Compounds [D01.625]
Nitrous Acid [D01.625.600]
Peroxynitrous Acid [D01.625.600.800]
Reactive Nitrogen Species [D01.625.700]
Peroxynitrous Acid [D01.625.700.750]

Below are MeSH descriptors whose meaning is related to "Peroxynitrous Acid".

Below are MeSH descriptors whose meaning is more specific than "Peroxynitrous Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peroxynitrous Acid" by people in this website by year, and whether "Peroxynitrous Acid" was a major or minor topic of these publications.

Bar chart showing 36 publications over 19 distinct years, with a maximum of 4 publications in 2010 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2003	0	3	3
2004	2	0	2
2005	1	0	1
2006	1	1	2
2007	0	1	1
2008	0	2	2
2010	2	2	4
2011	0	2	2
2012	2	0	2
2013	1	1	2
2014	1	1	2
2015	2	2	4
2016	0	1	1
2017	1	0	1
2018	1	2	3
2019	0	1	1
2020	1	0	1
2022	0	1	1

Below are the most recent publications written about "Peroxynitrous Acid" by people in Profiles.

Adelusi OB, Ramachandran A, Lemasters JJ, Jaeschke H. The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicol Appl Pharmacol. 2022 06 15; 445:116043.

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Louka S, Barry SM, Heyes DJ, Mubarak MQE, Ali HS, Alkhalaf LM, Munro AW, Scrutton NS, Challis GL, de Visser SP. Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate. J Am Chem Soc. 2020 09 16; 142(37):15764-15779.

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Albadrani M, Seth RK, Sarkar S, Kimono D, Mondal A, Bose D, Porter DE, Scott GI, Brooks B, Raychoudhury S, Nagarkatti M, Nagarkatti P, Jule Y, Diehl AM, Chatterjee S. Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G408-G428.

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Khan M, Dhammu TS, Singh I, Singh AK. Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity. BMC Neurosci. 2018 08 13; 19(1):50.

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Alhasson F, Seth RK, Sarkar S, Kimono DA, Albadrani MS, Dattaroy D, Chandrashekaran V, Scott GI, Raychoudhury S, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. Redox Biol. 2018 07; 17:1-15.

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Dasgupta S, Gomez JJ, Singh I, Khan M. S-Nitrosylation in Regulation of Inflammation and Cell Damage. Curr Drug Targets. 2018; 19(15):1831-1838.

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Hafez S, Abdelsaid M, Fagan SC, Ergul A. Peroxynitrite-Induced Tyrosine Nitration Contributes to Matrix Metalloprotease-3 Activation: Relevance to Hyperglycemic Ischemic Brain Injury and Tissue Plasminogen Activator. Neurochem Res. 2018 Feb; 43(2):259-266.

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Kenche H, Ye ZW, Vedagiri K, Richards DM, Gao XH, Tew KD, Townsend DM, Blumental-Perry A. Adverse Outcomes Associated with Cigarette Smoke Radicals Related to Damage to Protein-disulfide Isomerase. J Biol Chem. 2016 Feb 26; 291(9):4763-78.

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Dattaroy D, Seth RK, Das S, Alhasson F, Chandrashekaran V, Michelotti G, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. Am J Physiol Gastrointest Liver Physiol. 2016 04 01; 310(7):G510-25.

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Khan M, Dhammu TS, Matsuda F, Annamalai B, Dhindsa TS, Singh I, Singh AK. Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI. Brain Res. 2016 Jan 01; 1630:159-70.

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